Results 241 to 250 of about 509,731 (381)

Systemic T Cell Receptor Profiling Reveals Adaptive Immune Activation and Potential Immune Signatures of Diagnosis and Brain Atrophy in Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epilepsy is increasingly associated with immune dysregulation and inflammation. The T cell receptor (TCR), a key mediator of adaptive immunity, shows repertoire alterations in various immune‐mediated diseases. The unique TCR sequence serves as a molecular barcode for T cells, and clonal expansion accompanied by reduced overall TCR ...
Yong‐Won Shin, Sang Bin Hong, Yong Woo Shin, Inpyeong Hwang, Jaeseong Oh, Jihyeon Choi, Narae Kim, Jangsup Moon, Keun‐Hwa Jung, Kyung‐Il Park, Ki‐Young Jung, Kon Chu, Sang Kun Lee   +12 more
wiley   +1 more source

Unveiling the cut-and-repair cycle of designer nucleases in human stem and T cells via CLEAR-time dPCR. [PDF]

Nat Commun
White N, Chalk JA, Hu YT, Pins SM, Joseph CR, Antoniou P, Wimberger S, Svensson S, Caetano-Silva SP, Mudde ACA, Rai R, Selvaraj S, Feist WN, Romito M, Sienski G, Nitsch R, Booth C, Santilli G, Cavazza A, Porteus MH, Maresca M, Thrasher AJ, Turchiano G.   +22 more
europepmc   +1 more source

Polarization Aberrations in Astronomical Telescopes: The Point Spread Function

, 2015
J. Breckinridge, W. Lam, R. Chipman
semanticscholar   +1 more source

Purkinje Cell Loss in Essential Tremor: Collective Data From 215 Brains Over a 21‐Year Period

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Essential tremor is a highly prevalent movement disorder. Pathological changes observed in essential tremor cerebella center around Purkinje cells and neighboring neuronal populations. Postmortem studies have variably, but not always, shown reduced Purkinje cell counts in essential tremor compared to controls.
Chloë A. Kerridge, Roberto S. Hernandez, Nora C. Hernandez, Phyllis L. Faust, Elan D. Louis   +4 more
wiley   +1 more source

Compact way to generate guide star for wavefront sensing in Bessel two-photon microscopy. [PDF]

Sci Rep
Luo F, Li N, Yang C, Peng Z, Mu Q, Zhang X.   +5 more
europepmc   +1 more source

Identification and classification of chromosomal aberrations in human induced pluripotent stem cells.

Cell Stem Cell, 2010
Yoav Mayshar, U. Ben-David, Neta Lavon, J. Biancotti, B. Yakir, A. Clark, K. Plath, W. Lowry, N. Benvenisty   +8 more
semanticscholar   +1 more source

Expanding Hereditary Spastic Paraplegias Limits: Biallelic SPAST Variants in Cerebral Palsy Mimics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegias (HSP) are rare neurodegenerative disorders marked by spasticity and lower limb weakness. The most common type, SPG4, is usually autosomal dominant and caused by SPAST gene variants, typically presenting as pure HSP.
Gregorio A. Nolasco, Mònica Roldán, Yalda Jamshidi, Ioannis Georvasilis, Rocío Jadraque Rodríguez, Reza Boostani, Ali Shoeibi, Lluís Armengol, Anna Codina, Ehsan Ghayoor Karimiani, Cristina Hernando‐Davalillo, Loreto Martorell, María Luisa Ramírez Almaraz, Jordi Muchart, Carlos Ortez, Andrés Nascimento, Roser Urreizti, Daniel Natera‐de Benito, Mercedes Serrano   +18 more
wiley   +1 more source

Deep3DSIM: Super-resolution imaging of thick tissue using 3D structured illumination with adaptive optics. [PDF]

Elife
Wang J, Stoychev D, Phillips MA, Pinto DMS, Parton RM, Hall NJ, Titlow JS, Faria AR, Wincott M, Gala D, Gerondopoulos A, Irani N, Dobbie I, Schermelleh L, Booth MJ, Davis I.   +15 more
europepmc   +1 more source

Chromatic Aberrations in Optical Systems: Prediction and Correction

, 2012
Mehdi Bahrami
openalex   +2 more sources

Determining Resolution in an Aberration-Corrected Era: Why Your Probe Is Larger Than You Thought [PDF]

, 2010
Robert Hovden, HL Xin, David A. Muller
openalex   +1 more source