Results 71 to 80 of about 334,949 (278)

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Bauman MSTU scientific school “Zoom lens design”: features of theory and practice [PDF]

open access: yesКомпьютерная оптика, 2018
Key theoretical concepts advanced by the Bauman MSTU scientific school 'Zoom lens design' are discussed. These include methods for design of both classical and laser zoom lenses, systems with linear and nonlinear relations between the displacements of ...
Oleg Rozhkov   +5 more
doaj   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Wavefront analysis of a focus-tunable lens with gravity compensation

open access: yesJPhys Photonics
The application of focus-tunable lenses (FTL) has significantly expanded in the field of photonics in the last decade, establishing these devices as fundamental optoelectronic components in most experimental setups.
E Pérez-Cabré   +3 more
doaj   +1 more source

Combined conjugate and pupil adaptive optics in widefield microscopy [PDF]

open access: yes, 2016
Traditionally, adaptive optics (AO) systems for microscopy have focused on AO at the pupil plane, however this produces poor performance in samples with both spatially-variant aberrations, such as non-flat sample interfaces, and spatially-invariant ...
Beaulieu, Devin Robert
core   +1 more source

Exoplanet detection with simultaneous spectral differential imaging: effects of out-of-pupil-plane optical aberrations [PDF]

open access: yes, 2006
Imaging faint companions (exoplanets and brown dwarfs) around nearby stars is currently limited by speckle noise. To efficiently attenuate this noise, a technique called simultaneous spectral differential imaging (SSDI) can be used.
Macintosh, Bruce   +2 more
core   +2 more sources

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Radial thresholding to mitigate Laser-Guide-Star aberrations on Centre-of-Gravity-based Shack-Hartmann wavefront sensors

open access: yes, 2009
Sodium Laser Guide Stars (LGSs) are elongated sources due to the thickness and the finite distance of the sodium layer. The fluctuations of the sodium layer altitude and atom density profile induce errors on centroid measurements of elongated spots, and ...
Beletic   +18 more
core   +1 more source

Time-sequential Pipelined Imaging with Wavefront Coding and Super Resolution [PDF]

open access: yes, 2017
Wavefront coding has long offered the prospect of mitigating optical aberrations and extended depth of field, but image quality and noise performance are inevitably reduced. We report on progress in the use of agile encoding and pipelined fusion of image
Bradburn   +6 more
core   +1 more source

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