Active Control of Laser Wavefronts in Atom Interferometers
Wavefront aberrations are identified as a major limitation in quantum sensors. They are today the main contribution in the uncertainty budget of best cold atom interferometers based on two-photon laser beam splitters, and constitute an important limit ...
Langlois, Mehdi +3 more
core +2 more sources
Speckle noise reduction techniques for high-dynamic range imaging [PDF]
High-dynamic range imaging from space in the visible, aiming in particular at the detection of terrestrial exoplanets, necessitates not only the use of a coronagraph, but also of adaptive optics to correct optical defects in real time.
Belikov +23 more
core +3 more sources
Characterization of spatially varying aberrations for wide field-of-view microscopy. [PDF]
We describe a simple and robust approach for characterizing the spatially varying pupil aberrations of microscopy systems. In our demonstration with a standard microscope, we derive the location-dependent pupil transfer functions by first capturing ...
G. Zheng +3 more
semanticscholar +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Alpha-particle-induced complex chromosome exchanges transmitted through extra-thymic lymphopoiesis in vitro show evidence of emerging genomic instability [PDF]
Human exposure to high-linear energy transfer α-particles includes environmental (e.g. radon gas and its decay progeny), medical (e.g. radiopharmaceuticals) and occupational (nuclear industry) sources.
A Duran +66 more
core +2 more sources
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Holographic aberration correction: optimising the stiffness of an optical trap deep in the sample [PDF]
We investigate the effects of 1st order spherical aberration and defocus upon the stiffness of an optical trap tens of μm into the sample. We control both these aberrations with a spatial light modulator. The key to maintain optimum trap stiffness over a
Bowman +22 more
core +1 more source
Wavefront analysis of a focus-tunable lens with gravity compensation
The application of focus-tunable lenses (FTL) has significantly expanded in the field of photonics in the last decade, establishing these devices as fundamental optoelectronic components in most experimental setups.
E Pérez-Cabré +3 more
doaj +1 more source
Adaptive optics correction of specimen-induced aberrations in single-molecule switching microscopy
Single-molecule switching (SMS) microscopy is a super-resolution method capable of producing images with resolutions far exceeding that of the classical diffraction limit. However, like all optical microscopes, SMS microscopes are sensitive to, and often
Daniel Burke +4 more
semanticscholar +1 more source
The role of histone modifications in transcription regulation upon DNA damage
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source

