Results 41 to 50 of about 3,631,195 (345)
In Vitro Methods for Evaluating Drug Release of Vaginal Ring Formulations—A Critical Review
Pharmaceutics, 2019 The vagina is a promising site for both local and systemic drug delivery and represents an interesting administration route for compounds with poor oral bioavailability.
Katharina Tietz, Sandra Klein
doaj +1 more source
Purification tags markedly affect self‐aggregation of CPEB3
FEBS Letters, EarlyView.Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito +6 more
wiley +1 more source
Frontiers in Chemistry, 2021 The fluorescence-based optical imaging in the second near-infrared region (NIR-II, 1,000–1,700 nm) has broad applications in the biomedical field, but it is still difficult to find new NIR-II fluorescence materials in the two dimension.
Ke Yang, Tianyu Liu, Xiao-Dong Zhang
doaj +1 more source
, 2000 This is the edited transcript of a Witness Seminar held at the Wellcome Institute for the History of Medicine,in London, on 9 February 1999. First published by the Wellcome Trust, 2000.
Christie, DA, Tansey, EM
core
FEBS Letters, EarlyView.Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu +17 more
wiley +1 more source
Soliton absorption spectroscopy
, 2010 We analyze optical soliton propagation in the presence of weak absorption lines with much narrower linewidths as compared to the soliton spectrum width using the novel perturbation analysis technique based on an integral representation in the spectral ...
A. Biswas +10 more
core +2 more sources
Protective Properties of Health Care Materials Influenced by the Application Conditions [PDF]
Textile & Leather Review, 2018 The aim of the paper is to investigate protective function changes of reusuable fabrics used for standard (operations where these risks for penetration by liquids are lower) and high performance clothes (for operations with a high risk for penetration by
Beti Rogina-Car +2 more
doaj +1 more source
The anabolic steroid stanozolol is a potent inhibitor of human MutT homolog 1
FEBS Letters, EarlyView.MutT homolog 1 (MTH1) is a member of the NUDIX superfamily of enzymes and is an anticancer drug target. We show that stanozolol (Stz), an anabolic steroid, is an unexpected nanomolar inhibitor of MTH1. The X‐ray crystal structure of the human MTH1–Stz complex reveals a unique binding scaffold that could be utilized for future inhibitor development ...
Emma Scaletti Hutchinson +7 more
wiley +1 more source
The convolution theorem for nonlinear optics
, 2007 We have expressed the nonlinear optical absorption of a semiconductor in terms of its linear spectrum. We determined that the two-photon absorption coefficient in a strong DC-electric field of a direct gap semiconductor can be expressed as the product of
Franz W. +3 more
core +1 more source
Evidence for Photoionization Driven Broad Absorption Line Variability [PDF]
, 2015 We present a qualitative analysis of the variability of quasar broad absorption lines using the large multi-epoch spectroscopic dataset of the Sloan Digital Sky Survey Data Release 10. We confirm that variations of absorption lines are highly coordinated
Ferland, Gary +3 more
core +3 more sources