Results 41 to 50 of about 3,830,075 (379)

Impact of Tablet Size and Shape on the Swallowability in Older Adults

open access: yesPharmaceutics, 2023
Older adults represent the major target population for oral medications, due to the high prevalence of multimorbidity. To allow for successful pharmacological treatments, patients need to adhere to their medication and, thus, patient-centric drug ...
Henriette Hummler   +8 more
doaj   +1 more source

Fermionic greybody factors of two and five-dimensional dilatonic black holes [PDF]

open access: yes, 2014
We study fermionic perturbations in the background of a two and five-dimensional dilatonic black holes. Then, we compute the reflection and transmission coefficients and the absorption cross section for fermionic fields, and we show numerically that the ...
Becar, Ramón   +2 more
core   +2 more sources

Expression and Function of Organic Anion Transporting Polypeptides in the Human Brain: Physiological and Pharmacological Implications

open access: yesPharmaceutics, 2021
The central nervous system (CNS) is an important pharmacological target, but it is very effectively protected by the blood–brain barrier (BBB), thereby impairing the efficacy of many potential active compounds as they are unable to cross this barrier ...
Anima M. Schäfer   +2 more
doaj   +1 more source

A catalogue of absorption-line systems in QSO spectra

open access: yes, 2003
We present a new catalog of absprption-line systems identified in the quasar spectra. It contains data on 821 QSOs and 8558 absorption systems comprizing 16139 absorption lines with measured redshifts in the QSO spectra.
A. D. Kaminker   +16 more
core   +1 more source

Visible and Near-Infrared Broadband Absorber Based on Ti3C2Tx MXene-Wu

open access: yesNanomaterials, 2022
A high absorption broadband absorber based on MXene and tungsten nanospheres in visible and near-infrared bands is proposed. The absorber has a maximum absorption of 100% and an average absorption of 95% in the wavelength range of 400–2500 nm.
Yang Jia   +5 more
doaj   +1 more source

In vitro simulation of distribution processes following intramuscular injection

open access: yesCurrent Directions in Biomedical Engineering, 2016
There is an urgent need for in vitro dissolution test setups for intramuscularly applied dosage forms. Especially biorelevant methods are needed to predict the in vivo behavior of newly developed dosage forms in a realistic way.
Probst Mareike   +3 more
doaj   +1 more source

Anthocyanins as Key Phytochemicals Acting for the Prevention of Metabolic Diseases: An Overview

open access: yesMolecules, 2022
Anthocyanins are water-soluble pigments present in fruits and vegetables, which render them an extensive range of colors. They have a wide distribution in the human diet, are innocuous, and, based on numerous studies, have supposed preventive and ...
Madalina Nistor   +5 more
doaj   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

A BOILED‐Egg To Predict Gastrointestinal Absorption and Brain Penetration of Small Molecules

open access: yesChemMedChem, 2016
Apart from efficacy and toxicity, many drug development failures are imputable to poor pharmacokinetics and bioavailability. Gastrointestinal absorption and brain access are two pharmacokinetic behaviors crucial to estimate at various stages of the drug ...
Antoine Daina, V. Zoete
semanticscholar   +1 more source

In Vitro Methods for Evaluating Drug Release of Vaginal Ring Formulations—A Critical Review

open access: yesPharmaceutics, 2019
The vagina is a promising site for both local and systemic drug delivery and represents an interesting administration route for compounds with poor oral bioavailability.
Katharina Tietz, Sandra Klein
doaj   +1 more source

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