Background Pathogenic protozoans use extracellular vesicles (EVs) for intercellular communication and host manipulation. Acanthamoeba castellanii is a free-living protozoan that may cause severe keratitis and fatal granulomatous encephalitis.
Wei-Chen Lin +5 more
doaj +1 more source
Traditional cysticidal assays for Acanthamoeba species revolve around treating cysts with compounds and manually observing the culture for evidence of excystation. This method is time-consuming, labor-intensive, and low throughput. We adapted and trained
Brian Shing +3 more
doaj +1 more source
Infection of Acanthamoeba castellanii by Chlamydia pneumoniae [PDF]
Chlamydia pneumoniae is an intracellular respiratory pathogen, which, similar to Legionella, might have developed mechanisms to escape the intracellular bactericidal activity of both human host cells and amoeba. We therefore investigated the intracellular growth and survival of C.
A, Essig +3 more
openaire +2 more sources
A study of various environmental factors on the growth, encystment and survival of free living amoebae : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Microbiology at Massey University [PDF]
Free-living amoebae (FLA) are soil organisms which have a worldwide distribution. Interest was raised when they were implicated in two fatal and several non-fatal infections in humans. This investigation involved examination of the role and/or effect of
Rogers, Lynnette Helen
core
The Rising Dominance of Shigella sonnei: An Intercontinental Shift in the Etiology of Bacillary Dysentery. [PDF]
Shigellosis is the major global cause of dysentery. Shigella sonnei, which has historically been more commonly isolated in developed countries, is undergoing an unprecedented expansion across industrializing regions in Asia, Latin America, and the Middle
Baker, Stephen +2 more
core +3 more sources
Enhanced survival but not amplification of Francisella spp. in the presence of free-living amoebae [PDF]
Transmission of Francisella tularensis, the etiologic agent of tularemia, has been associated with various water sources. Survival of many waterborne pathogens within free-living amoeba (FLA) is well documented; however, the role of amoebae in the ...
Buse, Helen Y. +2 more
core +1 more source
Seasonal Host Shifts for Legionella Within an Industrial Water‐Cooling System
Taxonomic profiling for Legionella (the causative agent of Legionnaires' disease) and protist hosts within a water cooling tower showed seasonal peaks for Legionella that were associated with taxonomic shifts in the protist community. Legionella frequency was tracked using amplicon sequencing (blue line) and serogroup profiling (red line).
Suzanne Crull +8 more
wiley +1 more source
INTRODUCTION: Acanthamoeba species cause important diseases such as Acanthamoeba keratitis, granulomatous amoebic encephalitis and cutaneous acanthamoebiasis.
Bülent Kaynak +2 more
doaj +1 more source
The pathogenesis of Acanthamoeba infections: current status and future implications [PDF]
Acanthamoeba are opportunistic protozoan parasites that can cause painful, visionthreatening keratitis. However the pathogenesis and pathophysiology of Acanthamoeba keratitis remain incompletely understood. Most cases of Acanthamoeba keratitis develop
Khan, Naveed Ahmed
core
Luminal Phospholipase D Attacks Bacterial Membranes in Dictyostelium discoideum Phagosomes
This study shows that PldX, a luminal Phospholipase D, is necessary for the efficient destruction of ingested Klebsiella pneumoniae bacteria in Dictyostelium discoideum phagosomes. PldX and the AlyL lysozyme together attack the bacterial membrane and permeabilize it. To date, the molecular substrate of PldX remains to be determined. ABSTRACT Phagocytic
Otmane Lamrabet +6 more
wiley +1 more source

