Results 21 to 30 of about 3,485,354 (289)

Associations between alcohol use and accelerated biological ageing [PDF]

Addiction Biology, 2020
Abstract Harmful alcohol use is a leading cause of premature death and is associated with age‐related disease. Biological ageing is highly variable between individuals and may deviate from chronological ageing, suggesting that biomarkers of biological ageing (derived from DNA methylation or brain structural ...
Sunniva M. K. Bøstrand, Kadi Vaher, Laura De Nooij, Mathew A. Harris, James H. Cole, Simon R. Cox, Riccardo E. Marioni, Daniel L. McCartney, Rosie M. Walker, Andrew M. McIntosh, Kathryn L. Evans, Heather C. Whalley, Robyn E. Wootton, Toni-Kim Clarke   +13 more
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Association of adult lung function with accelerated biological aging [PDF]

Aging, 2020
Lung function, strongly associated with morbidity and mortality, decreases with age. This study examines whether poor adult lung function is associated with age accelerations (AAs). DNA methylation (DNAm) based AAs, lifespan predictors (GrimAge and plasminogen activator inhibitor 1-PAI1) and their related age-adjusted measures were estimated from ...
Rezwan, Faisal I., Imboden, Medea, Amaral, Andre F. S., Wielscher, Matthias, Jeong, Ayoung, Triebner, Kai, Real, Francisco Gómez, Jarvelin, Marjo-Riitta, Jarvis, Deborah, Probst-Hensch, Nicole M., Holloway, John W.   +10 more
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Aging on the Job? The Association Between Occupational Characteristics and Accelerated Biological Aging

The Journals of Gerontology: Series B, 2022
Abstract Objectives There is a common belief that demanding jobs can make workers age faster, but there is little empirical evidence linking occupational characteristics to accelerated biological aging.
Theresa Andrasfay, Jung Ki Kim, Jennifer A Ailshire, Eileen Crimmins   +3 more
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Editorial:Childhood Stress and Psychopathology: It's Not Too Early to Look at Biological Aging

, 2020
There has been growing interest in the associations among biological aging, stress, and psychopathology. Biological aging reflects an individual's functional and biological condition, and one of the indicators is telomere length.1 Telomeres consist of ...
Middeldorp, C.M., Middeldorp
core   +2 more sources

Chronic Inflammation: Accelerator of Biological Aging. [PDF]

The journals of gerontology. Series A, Biological sciences and medical sciences, 2017
Biological aging is characterized by a chronic low-grade inflammation level. This chronic phenomenon has been named "inflamm-aging" and is a highly significant risk factor for morbidity and mortality in the older persons. The most common theories of inflamm-aging include redox stress, mitochondrial dysfunction, glycation, deregulation of the immune ...
Fougère, Bertrand, Boulanger, Eric, Nourhashémi, Fati, Guyonnet, Sophie, M. Cesari   +4 more
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Aging in a Relativistic Biological Space-Time [PDF]

, 2018
Here we present a theoretical and mathematical perspective on the process of aging. We extend the concepts of physical space and time to an abstract, mathematically-defined space, which we associate with a concept of "biological space-time" in which ...
Russell C. Rockne, Kuo, Ya-Huei, Sergio Branciamore, Maestrini, Davide, Rockne, Russell C., Rockne, Russell C, Adhikarla, Vikram, Marcucci, Guido, Ya-Huei Kuo, Abler, Daniel, Carlesso, Nadia, Davide Maestrini, Guido Marcucci, Vikram Adhikarla, Prativa Sahoo, Armenian, Saro, Saro Armenian, Nadia Carlesso, Sahoo, Prativa, Daniel Abler, Branciamore, Sergio   +20 more
core   +3 more sources

Is biological aging accelerated in drug addiction? [PDF]

Current Opinion in Behavioral Sciences, 2017
Drug-addiction may trigger early onset of age-related disease, due to drug-induced multi-system toxicity and perilous lifestyle, which remains mostly undetected and untreated. We present the literature on pathophysiological processes that may hasten aging and its relevance to addiction, including: oxidative stress and cellular aging, inflammation in ...
Keren, Bachi, Salvador, Sierra, Nora D, Volkow, Rita Z, Goldstein, Nelly, Alia-Klein   +4 more
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Subjective Overview of Accelerated Aging in Schizophrenia [PDF]

, 2022
Schizophrenia, like many other human diseases, particularly neuropsychiatric diseases, shows evidence of accelerated brain aging. The molecular nature of the process of aging is unknown but several potential indicators have been used in research.
Mary V. Seeman, Seeman, Mary V.
core   +1 more source

Accelerated aging: A marker for social factors resulting in cardiovascular events?

SSM: Population Health, 2021
Background: Medicine and public health are shifting away from a purely “personal responsibility” model of cardiovascular disease (CVD) prevention towards a societal view targeting social and environmental conditions and how these result in disease. Given
Sarah N. Forrester, Rachel Zmora, Pamela J. Schreiner, David R. Jacobs, Jr., Veronique L. Roger, Roland J. Thorpe, Jr., Catarina I. Kiefe   +6 more
doaj   +1 more source

The NHANES Biological Age Index demonstrates accelerated aging in MS patients

Multiple Sclerosis and Related Disorders, 2023
Chronological age is associated with disability accumulation in multiple sclerosis (MS). Biological age may give more precise estimates of aging pathways associations with MS severity. Both normal aging and accelerated aging from MS may negatively impact disease course.
Annalise E. Miner, Jennifer H. Yang, Revere P. Kinkel, Jennifer S. Graves   +3 more
openaire   +2 more sources