Heterogeneity of aging and mortality risk among individuals with hypertension: Insights from phenotypic age and phenotypic age acceleration [PDF]
The Journal of Nutrition, Health and AgingObjectives: Hypertension, a key contributor to mortality, is impacted by biological aging. We investigated the relationship between novel biological aging metrics - Phenotypic Age (PA) and Phenotypic Age Acceleration (PAA) - and mortality in individuals ...
Yuntao Feng +3 more
doaj +7 more sources
Assessing thyroid health: phenotypic age compared to chronological age [PDF]
Frontiers in EndocrinologyIntroductionAging is associated with thyroid dysfunction, but the role of phenotypic age, a biological aging measure derived from nine clinical biomarkers and chronological age, remains unclear.MethodsThis cross-sectional study included 6,681 adults from
Dongyu Yang +8 more
doaj +4 more sources
Association between phenotypic age and in-hospital outcomes in patients with acute myocardial infarction: A retrospective observational study [PDF]
International Journal of Cardiology: Heart & VasculatureBackground: Phenotypic age (PhenoAge) has emerged as a superior predictor of age-related morbidity and mortality. This study aimed to assess the associations between PhenoAge and in-hospital outcomes in patients with acute myocardial infarction (AMI ...
Yajie Gao +7 more
doaj +4 more sources
Association between the dietary index for gut microbiota and diabetes: the mediating role of phenotypic age and body mass index [PDF]
Frontiers in NutritionObjectivesThe global prevalence of diabetes is continuously rising, and the gut microbiota is closely associated with it. The Dietary Index for Gut Microbiota (DI-GM) assesses the impact of diet on the microbiota, but its association with diabetes risk ...
Yingxuan Huang +7 more
doaj +4 more sources
Association of phenotypic age and accelerated aging with severity and disability in patients with acute ischemic stroke [PDF]
The Journal of Nutrition, Health and AgingObjective: Biological age may be more accurate than chronological age in determining chronic health outcomes. However, few studies have shown the association between biological age and acute ischemic stroke (AIS).
Yongkang Liu +7 more
doaj +4 more sources
Sex-specific associations between brominated flame retardants exposure and phenotypic age acceleration in NHANES 2005–2010 [PDF]
Frontiers in Public HealthBackgroundExposure to brominated flame retardants (BFRs) has been linked to age-related diseases. This study investigates the associations between both individual and combined BFRs exposures and phenotypic age acceleration (PhenoAgeAccel) in U.S.
Weiliang Kong, Yilian Xie, Yina Jin
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Association of cardiorespiratory fitness with phenotypic age in younger population: a study based on the NHANES database [PDF]
Frontiers in Sports and Active LivingBackgroundPhenotypic age (PA), a novel signature of morbidity and mortality risk based on clinically collected parameters, is considered one of the most promising biomarkers for capturing aging.
Yi Shen +6 more
doaj +2 more sources
Association of dietary inflammatory index and vigorous physical activity on phenotypic age acceleration: a cross-sectional study with machine learning [PDF]
Frontiers in NutritionBackgroundDiet and inflammation are intricately correlated to the aging process. Diet has also been hypothesized to influence aging by regulating inflammation.
Shuoqi Li +3 more
doaj +2 more sources
Heliyon, 2023 Prolonged sitting appears to accelerate aging, while optimal physical activity patterns have been found to delay the process. It is an emerging topic, and no conclusions have been reached regarding the relationship between physical activity patterns and ...
Yanwei You +5 more
doaj +3 more sources
Frontiers in NutritionPurposeThis study investigates the association between dietary Omega-3 fatty acid intake and accelerated phenotypic aging, referred to as PhenoAgeAccel. PhenoAgeAccel is defined as the difference between phenotypic biological age, calculated using blood ...
Dongzhe Wu +3 more
doaj +3 more sources