Results 31 to 40 of about 5,719,995 (296)

Age at onset and Parkinson disease phenotype [PDF]

open access: yesNeurology, 2016
To explore clinical phenotype and characteristics of Parkinson disease (PD) at different ages at onset in recently diagnosed patients with untreated PD.We have analyzed baseline data from the Parkinson's Progression Markers Initiative database. Four hundred twenty-two patients with a diagnosis of PD confirmed by DaTSCAN imaging were divided into 4 ...
PAGANO, GENNARO   +3 more
openaire   +4 more sources

Causal effect of gut microbiota on DNA methylation phenotypic age acceleration: a two-sample Mendelian randomization study

open access: yesScientific Reports, 2023
The causal relationship between gut microbiota and DNA methylation phenotypic age acceleration remains unclear. This study aims to examine the causal effect of gut microbiota on the acceleration of DNA methylation phenotypic age using Mendelian ...
Yedong Huang   +4 more
doaj   +1 more source

Characterization of Friesian Heifer Fertility under Egyptian Conditions [PDF]

open access: yesJournal of Animal and Poultry Production, 2020
Data from 3081 reproductive records of Friesian heifers covering the period from 1979 to 2013 belongs to Sakha and El-Karada experimental farms - Kafr-El-Sheikh Governorate, Animal Production Research Institute, Ministry of Agriculture, Egypt were ...
Anas Badr, S. Zahed
doaj   +1 more source

Towards a multidimensional healthy ageing phenotype [PDF]

open access: yesCurrent Opinion in Clinical Nutrition & Metabolic Care, 2016
There is great interest in developing tools to measure healthy ageing and to identify early stages of health impairment, which may guide the implementation of interventions to prevent or delay the development of disease, disability, and mortality. Here, we review the most recent developments directed to operationalize, and test, definitions of healthy ...
Mount, Sarah   +3 more
openaire   +3 more sources

Association between cardiometabolic index and biological aging in the US population: evidence from NHANES 2015–2020

open access: yesFrontiers in Aging Neuroscience
PurposeIt is crucial to identify biomarkers that influence the aging process and associated health risks, given the growing severity of the global population aging issue.
Miao Sun, Shuang Bao
doaj   +1 more source

Diagnostic Stability and Phenotypic Differences Among School-Age Children Diagnosed With ASD Before Age 2

open access: yesFrontiers in Psychiatry, 2022
Given the importance of early detection, it is critical to understand the non-linearity in manifestation of ASD before age 24 months, when ASD symptoms are beginning to consolidate, through the age of 36 months when stability of ASD diagnosis is ...
Rebecca J. Landa   +7 more
doaj   +1 more source

Neuropsychological and Educational Outcomes in Shwachman–Diamond Syndrome—A Report From the North American Shwachman–Diamond Syndrome Registry

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Shwachman–Diamond syndrome (SDS) is a rare autosomal recessive ribosomopathy characterized by bone marrow failure and multisystem involvement, with emerging evidence of associated neurocognitive impairment. Methods We conducted a retrospective study of 240 individuals with biallelic Shwachman–Bodian–Diamond syndrome (SBDS) mutations
Jane Koo   +11 more
wiley   +1 more source

The association between SII and aging: evidence from NHANES 1999–2018

open access: yesFrontiers in Public Health
BackgroundThe study aimed to examine the association between the systemic immune-inflammation index (SII), a contemporary metric of systemic inflammatory response, and biological aging, which are closely interconnected processes.MethodsThis cross ...
Nanbu Wang   +13 more
doaj   +1 more source

Age‐dependent phenotypes of ovarian endometriomas

open access: yesReproductive Medicine and Biology, 2022
AbstractPurposeTo analyze the characteristics of the ovarian endometrioma (OE) across the life span of a woman. In the past, the OE has traditionally been viewed as a single, monolithic disease. Today, there are emerging data indicating that OE phenotypes differ according to the age of the woman.MethodA narrative review of original articles on OE ...
Giuseppe Benagiano, Sun‐Wei Guo
openaire   +3 more sources

Effectiveness of Resistance Intradialytic Exercise Compared to Aerobic Intradialytic Exercise for Patients With Chronic Kidney Disease: A Randomized Controlled Clinical Trial

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Patients with chronic kidney disease undergoing hemodialysis commonly experience reduced physical function, fatigue, poor sleep quality, and impaired health‐related quality of life. Intradialytic exercise has been proposed as a non‐pharmacological strategy to improve these outcomes.
Klebson da Silva Almeida   +6 more
wiley   +1 more source

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