Results 11 to 20 of about 5,719,995 (296)

Evaluating the potential of phenotypic age to enhance cardiovascular risk prediction over chronological age in the UK Biobank [PDF]

Scientific Reports
Phenotypic age acceleration (PhenoAgeAccel) is a novel biological indicator estimates an individual’s mortality risk. The primary aim of this study was to evaluate the association between PhenoAge and PhenoAgeAccel with incident cardiovascular diseases ...
Kristine J. S. Kwan, Shi-Shuai Xie, Hai-Lei Li, Xue-Guang Lin, Yi-Jie Lu, Bo Chen, Kai-Xin Ge, Shu-Ya Tang, Hui Zhang, Shuai Jiang, Jing-Dong Tang   +10 more
doaj   +2 more sources

Age and Phenotype of Patients With Plaque Erosion [PDF]

Journal of the American Heart Association, 2021
Background A recent study reported that the outcome of patients with plaque erosion treated with stenting is poor when the underlying plaque is lipid rich. However, the detailed phenotype of patients with plaque erosion, particularly as related to different age groups, has not been systematically studied.
Araki, Makoto, Yonetsu, Taishi, Kurihara, Osamu, Nakajima, Akihiro, Lee, Hang, Soeda, Tsunenari, Minami, Yoshiyasu, Higuma, Takumi, Kimura, Shigeki, Takano, Masamichi, Yan, Bryan P., Adriaenssens, Tom, Boeder, Niklas F., Nef, Holger M., Kim, Chong Jin, McNulty, Iris, Crea, Filippo, Kakuta, Tsunekazu, Jang, Ik-Kyung   +18 more
openaire   +5 more sources

The Nutritional Phenotype in the Age of Metabolomics [PDF]

The Journal of Nutrition, 2005
The concept of the nutritional phenotype is proposed as a defined and integrated set of genetic, proteomic, metabolomic, functional, and behavioral factors that, when measured, form the basis for assessment of human nutritional status. The nutritional phenotype integrates the effects of diet on disease/wellness and is the quantitative indication of the
S H, Zeisel, H C, Freake, D E, Bauman, D M, Bier, D G, Burrin, J B, German, S, Klein, G S, Marquis, J A, Milner, G H, Pelto, K M, Rasmussen   +10 more
openaire   +2 more sources

Phenotypic age acceleration as a novel predictor of benign prostatic hyperplasia: a prospective cohort study [PDF]

GeroScience
Xiongjun Ye
exaly   +2 more sources

Molecular and phenotypic biomarkers of aging [PDF]

F1000Research, 2017
Individuals of the same age may not age at the same rate. Quantitative biomarkers of aging are valuable tools to measure physiological age, assess the extent of ‘healthy aging’, and potentially predict health span and life span for an individual. Given the complex nature of the aging process, the biomarkers of aging are multilayered and multifaceted ...
Xian Xia, Weiyang Chen, Joseph McDermott, Jing-Dong Jackie Han   +3 more
openaire   +2 more sources

Measuring the musculoskeletal aging phenotype [PDF]

Maturitas, 2016
The world is aging. The population aged over sixty years worldwide is predicted to rise from 841 million in 2013 to more than 2 billion by 2050. Musculoskeletal (MSK) disease is a significant burden on the aging population, contributing 7.5% of the disease burden in those aged over 60 years. MSK diseases have a pronounced effect on disability level and
Dawson, Alice, Dennison, Elaine
openaire   +4 more sources

Phenotypic flexibility and the evolution of organismal design [PDF]

, 2003
Evolutionary biologists often use phenotypic differences between species and between individuals to gain an understanding of organismal design. The focus of much recent attention has been on developmental plasticity – the environmentally induced ...
Piersma, T, Drent, Jan,, Piersma, Theunis,, Piersma, T; id_orcid, Drent, J   +4 more
core   +2 more sources

Heritability of the Fibromyalgia Phenotype Varies by Age [PDF]

Arthritis & Rheumatology, 2020
ObjectiveMany studies suggest a strong familial component to fibromyalgia (FM). However, those studies have nearly all been confined to individuals with primary FM, i.e., FM without any other accompanying disorder. The current 2011 and 2016 criteria for diagnosing FM construct a score using a combination of the number of painful body sites and the ...
Diptavo Dutta, Chad M. Brummett, Stephanie E. Moser, Lars G. Fritsche, Alexander Tsodikov, Seunggeun Lee, Daniel J. Clauw, Laura J. Scott   +7 more
openaire   +3 more sources

Rapid enzymatic test for phenotypic HIV protease drug resistance [PDF]

, 2003
A phenotypic resistance test based on recombinant expression of the active HIV protease in E. coli from patient blood samples was developed. The protease is purified in a rapid onestep procedure as active enzyme and tested for inhibition by five selected
Machleidt, Werner, Hoffmann, D., Assfalg-Machleidt, Irmgard, Helm, K. von der, Nitschko, H., Koszinowski, U.   +5 more
core   +1 more source

Computational models for prediction of yeast strain potential for winemaking from phenotypic profiles [PDF]

, 2013
Saccharomyces cerevisiae strains from diverse natural habitats harbour a vast amount of phenotypic diversity, driven by interactions between yeast and the respective environment. In grape juice fermentations, strains are exposed to a wide array of biotic
Mendes, Mendes, Dequin, Sylvie, Schuller, Dorit, João Drumonde-Neves, Ricardo Franco-Duarte, Inês Mendes, João Drumonde-Neves (433942), Mendes Inês, Fonseca Elza, Elza Fonseca (433941), Schuller, Dorit Elisabeth, Fonseca, Elza, Zupan Blaz, Lan Umek, Schuller Dorit, Sylvie Dequin (205208), Dorit Schuller (181699), Franco-Duarte, Ricardo, Sylvie Dequin, Dequin Sylvie, Dorit Schuller, Zupan, Blaz, Umek, Lan, Drumonde-Neves João, Mendes, Inês Isabel Moreira Moutinho Vieira, Lan Umek (433940), Drumonde-Neves, Joao, Umek Lan, Inês Mendes (433938), Elza Fonseca, Blaz Zupan (10031), Mendes, Ines, Franco-Duarte Ricardo, Ricardo Franco-Duarte (433939), Blaz Zupan   +34 more
core   +2 more sources