Heterogeneity of aging and mortality risk among individuals with hypertension: Insights from phenotypic age and phenotypic age acceleration [PDF]
The Journal of Nutrition, Health and AgingObjectives: Hypertension, a key contributor to mortality, is impacted by biological aging. We investigated the relationship between novel biological aging metrics - Phenotypic Age (PA) and Phenotypic Age Acceleration (PAA) - and mortality in individuals ...
Yuntao Feng +3 more
doaj +7 more sources
Causal effect of gut microbiota on DNA methylation phenotypic age acceleration: a two-sample Mendelian randomization study [PDF]
Scientific Reports, 2023 The causal relationship between gut microbiota and DNA methylation phenotypic age acceleration remains unclear. This study aims to examine the causal effect of gut microbiota on the acceleration of DNA methylation phenotypic age using Mendelian ...
Yedong Huang +4 more
doaj +3 more sources
Dose-response relationship between leisure-time physical activity patterns and phenotypic age acceleration in American adults: A cross-sectional analysis [PDF]
Journal of Exercise Science & FitnessBackground/Objectives: With the accelerating global population aging, delaying aging and promoting healthy aging have become focal points in public health and clinical medicine.
Dongzhe Wu +9 more
doaj +5 more sources
Dose–response relationship of dietary Omega-3 fatty acids on slowing phenotypic age acceleration: a cross-sectional study [PDF]
Frontiers in NutritionPurposeThis study investigates the association between dietary Omega-3 fatty acid intake and accelerated phenotypic aging, referred to as PhenoAgeAccel. PhenoAgeAccel is defined as the difference between phenotypic biological age, calculated using blood ...
Dongzhe Wu +3 more
doaj +4 more sources
Psoriasis and phenotypic age acceleration in relation to all-cause and cardiovascular disease mortality risks in US adults [PDF]
European Journal of Medical ResearchBackground Psoriasis is a chronic, immune-mediated inflammatory dermatosis associated with an elevated risk of cardiovascular disease (CVD) due to systemic inflammation and metabolic dysregulation.
Wen-Qi Zhao +3 more
doaj +3 more sources
Association between triglyceride-glucose index and phenotypic age acceleration: a cross-sectional study based on NHANES database [PDF]
Frontiers in PhysiologyObjectiveTo investigate the association between triglyceride-glucose (TyG) index and phenotypic age acceleration (PhenoAgeAccel), given the emerging importance of biological aging as a health determinant and the role of insulin resistance in aging ...
Zhili Zhao +3 more
doaj +4 more sources
Association of visceral adiposity index with phenotypic age acceleration: insight from NHANES 1999–2010 [PDF]
The Journal of Nutrition, Health and AgingBackground: Obesity correlates with accelerated aging. This study aims to investigate the association between the visceral adiposity index (VAI) and accelerated aging. Methods: Biological aging was evaluated by phenotypic age acceleration (PhenoAgeAccel).
Cheng Xu +3 more
doaj +4 more sources
Associations between Life’s Crucial 9 and severity, all-cause mortality, and cardiovascular mortality in individuals with cardiovascular-kidney-metabolic syndrome: the mediating role of phenotypic age acceleration [PDF]
Frontiers in NutritionObjectiveThe American Heart Association (AHA) recently introduced the concept of cardiovascular-kidney-metabolic (CKM) syndrome. This study aimed to explore the associations of Life’s Crucial 9 (LC9), the recently updated lifestyle guidelines for ...
Jing Li +8 more
doaj +4 more sources
Sex-specific associations between brominated flame retardants exposure and phenotypic age acceleration in NHANES 2005–2010 [PDF]
Frontiers in Public HealthBackgroundExposure to brominated flame retardants (BFRs) has been linked to age-related diseases. This study investigates the associations between both individual and combined BFRs exposures and phenotypic age acceleration (PhenoAgeAccel) in U.S.
Weiliang Kong, Yilian Xie, Yina Jin
doaj +4 more sources
Association of weight-adjusted-waist index with phenotypic age acceleration: Insight from NHANES 2005–2010 [PDF]
The Journal of Nutrition, Health and AgingShanshan Jia +4 more
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