Results 1 to 10 of about 551 (111)

The mixed effect of Endocrine-Disrupting chemicals on biological age Acceleration: Unveiling the mechanism and potential intervention target

Environment International
Introduction: Although previous studies investigated the potential adverse effects of endocrine-disrupting chemicals (EDCs) on biological age acceleration and aging-related diseases, the mixed effect of multiple types of EDCs on biological age ...
Weichao Huang, Zilong Zhang, Manuel Colucci, Linghui Deng, Mi Yang, Xinyi Huang, Xianghong Zhou, Yumin Jin, Edoardo Lazzarini, Carolina Balbi, Oriol Juanola, Aurora Valdata, Silvia Bressan, Yu Zhan, Fang Qi, Qiang Wei, Lu Yang, Xiaoli Zou, Shi Qiu   +18 more
doaj   +3 more sources

Associations between anthropometric indices and biological age acceleration in American adults: insights from NHANES 2009–2018 data

Scientific Reports
Population aging has become a global phenomenon with significant implications for public health. Aging accelerates the development of age-related diseases, leading to increased social and economic burdens.
Xinyun Chen, Xia Chen, Fangyu Shi, Wenhui Yu, Chang Gao, Shenju Gou, Ping Fu   +6 more
doaj   +2 more sources

Evidence for Biological Age Acceleration and Telomere Shortening in COVID-19 Survivors [PDF]

International Journal of Molecular Sciences, 2021
ABSTRACT Introduction & Background the SARS-CoV-2 infection determines the COVID19 syndrome characterized, in the worst cases, by severe respiratory distress, pulmonary and cardiac fibrosis, inflammatory cytokines release, and immunosuppression.
Sandra Atlante, Veronica Barbi, Alessia Mongelli   +2 more
exaly   +7 more sources

Association of uric acid to high-density cholesterol ratio (UHR) with biological age acceleration: evidence from NHANES 2009–2018

Scientific Reports
The global population is rapidly aging, presenting significant public health challenges, particularly with the increased risk of chronic diseases. Biological age acceleration refers to a faster-than-expected aging process, which is associated with an ...
Xinyun Chen, Hui Dong, Fangyu Shi, Feng Qin, Ying Zhao   +4 more
doaj   +2 more sources

Chemotherapy-induced acceleration of DNA methylation-based biological age in breast cancer

Epigenetics
Breast cancer is the most common cancer diagnosed in women and is often treated with chemotherapy. Although previous studies have demonstrated increasing biological age in patients who receive chemotherapy, evaluation of this association with DNA ...
Drew R. Nannini, Rene Cortese, Christopher VonTungeln, Gerhard C. Hildebrandt   +3 more
doaj   +3 more sources

Epigenetic and biological age acceleration in children with atopic dermatitis

Journal of Allergy and Clinical Immunology: Global
Background: Atopic dermatitis (AD) is a chronic inflammatory skin disease resulting from the complex interplay of genetic and environmental factors, meriting exploration using temporally dynamic biomarkers.
Richie Jeremian, PhD, Alexandra Malinowski, PhD, Edward S. Oh, PhD, Melinda Gooderham, MD, MSc, FRCPC, Cathryn Sibbald, MD, MSc, FRCPC, Jensen Yeung, MD, FRCPC, Yuka Asai, MD, FRCPC, Vincent Piguet, MD, PhD, FRCP, Carolyn S. Jack, MDCM, PhD, FRCPC   +8 more
doaj   +3 more sources

Biological aging matters: a cross-sectional study uncovering the association between phenotypic age acceleration and erectile dysfunction based on 2360 male individuals

The Aging Male
Background The current study aimed to explore the potential associations between Phenotypic Age (PhenoAge)/PhenoAge acceleration (PhenoAgeAccel) and erectile dysfunction (ED).Methods We carried out a cross-sectional study based on data from 2360 male ...
Fan Dong, Ping Ping, Yi Ma, Xiang-Feng Chen   +3 more
doaj   +3 more sources

Accelerated Aging of Forensically Relevant Biological Materials on Swabs [PDF]

BioTechniques, 2021
The preservation of DNA in biological samples is important for forensic testing, as samples can be tested years or even decades after collection. Generally, the DNA within biological evidence is stable over shorter time frames but can degrade over extended periods.
Abigail S Bathrick, Jon M Davoren
openaire   +3 more sources

Accelerated biological aging in COVID-19 patients

Nature Communications, 2022
Abstract Chronological age is a risk factor for SARS-CoV-2 infection and severe COVID-19. Previous findings indicate that epigenetic age could be altered in viral infection. However, the epigenetic aging in COVID-19 has not been well studied.
Xue Cao, Wenjuan Li, Ting Wang, Dongzhi Ran, Veronica Davalos, Laura Planas-Serra, Aurora Pujol, Manel Esteller, Xiaolin Wang, Huichuan Yu   +9 more
openaire   +8 more sources

Menopause accelerates biological aging [PDF]

Proceedings of the National Academy of Sciences, 2016
Significance Within an evolutionary framework, aging and reproduction are intrinsically linked. Although both laboratory and epidemiological studies have observed associations between the timing of reproductive senescence and longevity, it is not yet known whether differences in the age of menopause are reflected in biomarkers of ...
Levine, Morgan E, Lu, Ake T, Chen, Brian H, Hernandez, Dena G, Singleton, Andrew B, Ferrucci, Luigi, Bandinelli, Stefania, Salfati, Elias, Manson, JoAnn E, Quach, Austin, Kusters, Cynthia DJ, Kuh, Diana, Wong, Andrew, Teschendorff, Andrew E, Widschwendter, Martin, Ritz, Beate R, Absher, Devin, Assimes, Themistocles L, Horvath, Steve   +18 more
openaire   +5 more sources