Results 31 to 40 of about 7,692,235 (287)

Developmental fitness curves: assessing sprint acceleration relative to age and maturity status in elite junior tennis players

Annals of Human Biology, 2020
Background The influence of maturity-status on athletic performance is reasonably well-documented. Methodological and practical issues of assessment and lack of longitudinal data have impacted the success of various models.
Gillian K. Myburgh, Sean P. Cumming, Manuel Coelho-e-Silva, Robert M. Malina   +3 more
doaj   +1 more source

The early-life exposome and epigenetic age acceleration in children

Environment International, 2021
The early-life exposome influences future health and accelerated biological aging has been proposed as one of the underlying biological mechanisms. We investigated the association between more than 100 exposures assessed during pregnancy and in childhood
Paula de Prado-Bert, Carlos Ruiz-Arenas, Marta Vives-Usano, Sandra Andrusaityte, Solène Cadiou, Ángel Carracedo, Maribel Casas, Leda Chatzi, Payam Dadvand, Juan R. González, Regina Grazuleviciene, Kristine B. Gutzkow, Line S. Haug, Carles Hernandez-Ferrer, Hector C. Keun, Johanna Lepeule, Léa Maitre, Rosie McEachan, Mark J. Nieuwenhuijsen, Dolors Pelegrí, Oliver Robinson, Rémy Slama, Marina Vafeiadi, Jordi Sunyer, Martine Vrijheid, Mariona Bustamante   +25 more
doaj   +1 more source

Prenatal Air Pollution and Newborns' Predisposition to Accelerated Biological Aging [PDF]

Obstetrical & Gynecological Survey, 2017
(Abstracted from JAMA Pediatr 2017;171(12):1160–1167) Telomere length (TL) is considered a molecular marker of biological aging. Telomeres shorten with each cellular division, and their length is associated with age-related diseases, lifestyle factors such as smoking, and environmental factors that influence the oxidative stress and ...
Dries S. Martens, Bianca Cox, Bram G. Janssen, Diana B. P. Clemente, Antonio Gasparrini, Charlotte Vanpoucke, Wouter Lefebvre, Harry A. Roels, Michelle Plusquin, Tim S. Nawrot   +9 more
openaire   +3 more sources

Biological aging, circulating lipid biomarkers and pancreatic diseases: a prospective cohort study based on the UK Biobank

The Journal of Nutrition, Health and Aging
Background: Biological aging refers to gradual declines in overall physiological function and can raise susceptibility to diseases. However, whether biological age acceleration is associated with pancreatic diseases remains unclear.
Hang Zhang, Junwei Huang, Peiyu Lin, Jiayin Song, Chonghui Hu, Biaojun Lin, Lingdan Le, Shangyou Zheng   +7 more
doaj   +1 more source

Biological Age in COPD Patients Reveals an Accelerated Lung Aging [PDF]

, 2021
Abstract Chronic obstructive pulmonary disease (COPD), the third leading cause of death worldwide, shows striking clinical aging-associated features of lung. We tested the hypothesis that lung biological aging in COPD is accelerated. Biological aging was assessed by mitotic telomere length (TL) and non-mitotic age-dependent methylation changes ...
Manuela Campisi, Filippo Liviero, Piero Maestrelli, Gabriella Guarnieri, Sofia Pavanello   +4 more
openaire   +1 more source

The epigenetic clock and objectively measured sedentary and walking behavior in older adults: the Lothian Birth Cohort 1936

Clinical Epigenetics, 2018
Background Estimates of biological age derived from DNA-methylation patterns—known as the epigenetic clock—are associated with mortality, physical and cognitive function, and frailty, but little is known about their relationship with sedentary behavior ...
Catharine R. Gale, Riccardo E. Marioni, Iva Čukić, Sebastien F. Chastin, Philippa M. Dall, Manon L. Dontje, Dawn A. Skelton, Ian J. Deary, on behalf of the Seniors USP Team   +8 more
doaj   +1 more source

Parity predicts biological age acceleration in post-menopausal, but not pre-menopausal, women

Scientific Reports, 2020
Understanding factors contributing to variation in ‘biological age’ is essential to understanding variation in susceptibility to disease and functional decline. One factor that could accelerate biological aging in women is reproduction.
Talia N. Shirazi, Waylon J. Hastings, Asher Y. Rosinger, Calen P. Ryan   +3 more
doaj   +1 more source

Hemophilia is associated with accelerated biological aging

Haematologica
Hemophilia is a rare X-linked bleeding disorder caused by mutations in the F8 or F9 gene (hemophilia A or B), leading to deficient factor VIII or IX proteins, respectively. Hemophilia-related complications caused by bleeding into the joints (the hallmark of hemophilia) and age-related comorbidities occur frequently and impact the functionality and ...
Marina Trappl, Rafaela Vostatek, Manuel Salzmann, Daniel Kraemmer, Johanna Gebhart, Philipp Hohensinner, Ingrid Pabinger, Cihan Ay   +7 more
openaire   +4 more sources

Epigenetic Age Acceleration and Chronological Age: Associations With Cognitive Performance in Daily Life [PDF]

DNA methylation-derived epigenetic clocks offer the opportunity to examine aspects of age acceleration (ie, the difference between an individual's biological age and chronological age), which vary among individuals and may better account for age-related ...
Reid, Kerry, Sliwinski, Martin, Harrington, Karra D., Pasquini, Giancarlo, Zavala, Daisy V., Bernard, Kristin, Gopalan, Shyamalika, Scott, Stacey B., Dzikowski, Natalie, Mogle, Jacqueline, Graham-Engeland, Jennifer E., Veeramah, Krishna, Engeland, Christopher G.   +12 more
core   +1 more source

Accelerated biological aging as potential mediator in the relationship between central obesity and lung cancer risk

Frontiers in Aging
BackgroundThe increased prevalence of obesity and incidence of lung cancer have raised significant concerns worldwide. However, the relationship between obesity and lung cancer risk, and the potential mediating effect of biological aging remains poorly ...
Hongya Liu, Hongya Liu, Zhihao Deng, Zhihao Deng, Zhongwen Gong, Zhongwen Gong, Yangjiao Bai, Yongjia Li, Qing Zhou, Jian Ma, Jian Ma, Jing Gao, Xuemei Lian, Xuemei Lian   +13 more
doaj   +1 more source