Results 41 to 50 of about 7,692,235 (287)

Acceleration in turbulent channel flow

open access: yes, 2010
We use Direct Numerical Simulations of turbulent channel flow to study the acceleration A corresponding to the full fluid velocity u and the acceleration a corresponding to the fluctuating velocity u? ? u?hui where hui is the mean flow.
S. W. Coleman   +7 more
core   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Acceleration: An interpretive study of gifted students within a primary school setting [PDF]

open access: yes, 2009
The purpose of this study was to investigate the experiences of gifted Primary School aged students who had been year level accelerated in Western Australia.
Gamble, Christina
core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Association between blood-derived biological aging and bone mineral density among US adults

open access: yesBMC Musculoskeletal Disorders
Objective Little is known regarding the association between biological aging and bone mineral density (BMD). This study aimed to assess the effects of biological aging on BMD in US adults.
Longyun Wu   +4 more
doaj   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Dissociation of biological age and blood interleukins in patients aged 45–59 years with diabetic retinopathy in type 2 diabetes mellitus

open access: yesActa Biomedica Scientifica, 2023
Background. The development of diabetic retinopathy is favoured by immunological factors such as interleukins (IL) and chemokines. However, analysis of blood interleukins in patients aged 45–59 years with diabetic retinopathy in type 2 diabetes mellitus,
I. V. Lev, N. M. Agarkov, A. E. Kopylov
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Construction of a new biological age model based on NHANES database and its predictive role for mortality outcomes

open access: yes陆军军医大学学报
Objective‍ ‍To develop a new biological age model based on the National Health and Nutrition Examination Survey (NHANES) database and evaluate its predictive performance for mortality outcomes.
YE Tingting, GAO Pan
doaj   +1 more source

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