Results 21 to 30 of about 7,692,235 (287)
Retraction to Chronic Inflammation: Accelerator of Biological Aging [PDF]
The Journals of Gerontology: Series A, 2019 Biological aging is characterized by a chronic low-grade inflammation level. This chronic phenomenon has been named "inflamm-aging" and is a highly significant risk factor for morbidity and mortality in the older persons. The most common theories of inflamm-aging include redox stress, mitochondrial dysfunction, glycation, deregulation of the immune ...
Fougère, Bertrand +4 more
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DOES AGEISM ACCELERATE BIOLOGICAL AGING
Innovation in Aging, 2022 Abstract Defined as, “stereotype, prejudice, and discrimination directly towards people because of their age”, ageism may contribute to adverse health outcomes, accelerate aging process, and increase the burden on health and social services. Little is known about the ageism impact on biological aging.
Liu, Mingxin +5 more
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The Journals of Gerontology: Series B, 2022 Abstract Objectives There is a common belief that demanding jobs can make workers age faster, but there is little empirical evidence linking occupational characteristics to accelerated biological aging.
Theresa Andrasfay +3 more
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Associations between alcohol use and accelerated biological ageing [PDF]
Addiction Biology, 2020 Abstract Harmful alcohol use is a leading cause of premature death and is associated with age‐related disease. Biological ageing is highly variable between individuals and may deviate from chronological ageing, suggesting that biomarkers of biological ageing (derived from DNA methylation or brain structural ...
Sunniva M. K. Bøstrand +13 more
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Association of adult lung function with accelerated biological aging [PDF]
Aging, 2020 Lung function, strongly associated with morbidity and mortality, decreases with age. This study examines whether poor adult lung function is associated with age accelerations (AAs). DNA methylation (DNAm) based AAs, lifespan predictors (GrimAge and plasminogen activator inhibitor 1-PAI1) and their related age-adjusted measures were estimated from ...
Rezwan, Faisal I. +10 more
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Is biological aging accelerated in drug addiction? [PDF]
Current Opinion in Behavioral Sciences, 2017 Drug-addiction may trigger early onset of age-related disease, due to drug-induced multi-system toxicity and perilous lifestyle, which remains mostly undetected and untreated. We present the literature on pathophysiological processes that may hasten aging and its relevance to addiction, including: oxidative stress and cellular aging, inflammation in ...
Keren, Bachi +4 more
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Chronic Inflammation: Accelerator of Biological Aging. [PDF]
The journals of gerontology. Series A, Biological sciences and medical sciences, 2017 Biological aging is characterized by a chronic low-grade inflammation level. This chronic phenomenon has been named "inflamm-aging" and is a highly significant risk factor for morbidity and mortality in the older persons. The most common theories of inflamm-aging include redox stress, mitochondrial dysfunction, glycation, deregulation of the immune ...
Fougère, Bertrand +4 more
openaire +4 more sources
Multi-omic underpinnings of epigenetic aging and human longevity
Nature Communications, 2023 Biological aging is accompanied by increasing morbidity, mortality, and healthcare costs; however, its molecular mechanisms are poorly understood. Here, we use multi-omic methods to integrate genomic, transcriptomic, and metabolomic data and identify ...
Lucas A. Mavromatis +5 more
doaj +1 more source
Epigenetic clocks derived from western samples differentially reflect Taiwanese health outcomes
Frontiers in Genetics, 2023 Introduction: Several epigenetic clocks have been developed, with five measures of epigenetic age acceleration (EAA) especially receiving extensive investigations: HannumEAA, IEAA, PhenoEAA, GrimEAA, and DunedinPACE.
Wan-Yu Lin, Wan-Yu Lin, Wan-Yu Lin
doaj +1 more source
The NHANES Biological Age Index demonstrates accelerated aging in MS patients
Multiple Sclerosis and Related Disorders, 2023 Chronological age is associated with disability accumulation in multiple sclerosis (MS). Biological age may give more precise estimates of aging pathways associations with MS severity. Both normal aging and accelerated aging from MS may negatively impact disease course.
Annalise E. Miner +3 more
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