Results 21 to 30 of about 5,719,995 (296)

Association of Phenotypic Aging Marker with comorbidities, frailty and inflammatory markers in people living with HIV

BMC Geriatrics, 2022
Background Aging characteristics in people living with HIV (PLWH) are heterogeneous, and the identification of risk factors associated with aging-related comorbidities such as neurocognitive impairment (NCI) and frailty is important.
Win Min Han, Tanakorn Apornpong, Sivaporn Gatechompol, Sasiwimol Ubolyam, Pairoj Chattranukulchai, Lalita Wattanachanya, Sarawut Siwamogsatham, Stephen J. Kerr, Kristine M. Erlandson, Anchalee Avihingsanon   +9 more
doaj   +1 more source

Associations between cadmium exposure and whole-body aging: mediation analysis in the NHANES

BMC Public Health, 2023
Introduction Even though cadmium (Cd) exposure and cellular senescence (telomere length) have been linked in previous studies, composite molecular aging biomarkers are more significant and reliable factors to consider when examining the connection ...
Ya Zhang, Mingjiang Liu, Ruijie Xie
doaj   +1 more source

Measuring Aging and Identifying Aging Phenotypes in Cancer Survivors [PDF]

JNCI: Journal of the National Cancer Institute, 2019
Abstract Observational data have shown that some cancer survivors develop chronic conditions like frailty, sarcopenia, cardiac dysfunction, and mild cognitive impairment earlier and/or at a greater burden than similarly aged individuals never diagnosed with cancer or exposed to systemic or targeted cancer therapies. In aggregate, cancer-
Jennifer L Guida, Tim A Ahles, Daniel Belsky, Judith Campisi, Harvey Jay Cohen, James DeGregori, Rebecca Fuldner, Luigi Ferrucci, Lisa Gallicchio, Leonid Gavrilov, Natalia Gavrilova, Paige A Green, Chamelli Jhappan, Ronald Kohanski, Kevin Krull, Jeanne Mandelblatt, Kirsten K Ness, Ann O’Mara, Nathan Price, Jennifer Schrack, Stephanie Studenski, Olga Theou, Russell P Tracy, Arti Hurria   +23 more
openaire   +2 more sources

Comment on “Fatigability: A Prognostic Indicator of Phenotypic Aging” [PDF]

The Journals of Gerontology: Series A, 2021
nonPeerReviewed
Portegijs, Erja, Karavirta, Laura, Rantanen, Taina, Palmberg, Lotta   +4 more
openaire   +3 more sources

Association between triglyceride-glucose index and phenotypic age acceleration: a cross-sectional study based on NHANES database [PDF]

Frontiers in Physiology
Zhao Z, Liang Y.
exaly   +2 more sources

Phenotype of Spirometric Impairment in an Aging Population [PDF]

American Journal of Respiratory and Critical Care Medicine, 2016
Abstract Rationale The Global Lung Initiative (GLI) provides age-appropriate criteria for establishing spirometric impairment, including mild, moderate, and severe chronic obstructive pulmonary disease (COPD) and restrictive pattern, but its association with respiratory-related phenotypes has ...
Fragoso, Carlos A Vaz, McAvay, Gail, Van Ness, Peter H, Casaburi, Richard, Jensen, Robert L, MacIntyre, Neil, Yaggi, H Klar, Gill, Thomas M, Concato, John   +8 more
openaire   +4 more sources

U-shaped association between serum Klotho and accelerated aging among the middle-aged and elderly US population: a cross-sectional study

BMC Geriatrics, 2023
Background Phenotypic age acceleration, which reflects the difference between phenotypic age and chronological age, is an assessment to measure accelerated aging.
Heng Li, Shuai Miao, Min Zhang, Peng Zhang, Yan-Bin Li, Rui-Sheng Duan   +5 more
doaj   +1 more source

Association of serum 25(OH)D3 and cognitive levels with biological aging in the elderly: a cross-sectional study

Frontiers in Nutrition
BackgroundBiological aging, a fundamental process affecting health and longevity, is pivotal to understanding the physiological decline associated with aging.
Mingkai Li, Chenyang Li, Le Cheng, Chenhui Lv, Lushan Xue, Cheng Zhang, Ziping Bai, Xi Wang, Shuangzhi Chen, Qinfei Guo, Yafei Zhao, Haifeng Zhao, Haifeng Zhao   +12 more
doaj   +1 more source

Microglia Phenotypes in Aging and Neurodegenerative Diseases

Cells, 2022
Neuroinflammation is a hallmark of many neurodegenerative diseases (NDs) and plays a fundamental role in mediating the onset and progression of disease. Microglia, which function as first-line immune guardians of the central nervous system (CNS), are the central drivers of neuroinflammation.
Menbere Y. Wendimu, Shelley B. Hooks
openaire   +3 more sources

The association of clinical and biochemical indicators with the rate of aging in patients with arterial hypertension during wartime

Arterial Hypertension
BACKGROUND: Our study aimed to assess changes in the levels of clinical and biochemical parameters, as well as aging markers in blood, over different treatment periods in arterial hypertension (HTN) patients during wartime, and to compare the obtained ...
Olena V. Kolesnikova, Anastasiia Olegivna Radchenko, Olga Ye Zaprovalna   +2 more
doaj   +1 more source