Results 41 to 50 of about 3,485,354 (289)

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Supplemental Material, BMD_Supplementary_Table - Accelerated Aging: The Role of Socioeconomic, Social, Demographic, and Biological Factors on Bone Mineral Density

, 2018
Supplemental Material, BMD_Supplementary_Table for Accelerated Aging: The Role of Socioeconomic, Social, Demographic, and Biological Factors on Bone Mineral Density by Margaret Gough, and Kanya Godde in Research on ...
Margaret Gough (6076904), Kanya Godde (6076907)   +1 more
core   +1 more source

Navigating Black Aging: The Biological Consequences of Stress and Depression [PDF]

, 2022
OBJECTIVES: Black persons in the US are more likely to suffer from social inequality. Chronic stress caused by social inequality and racial discrimination results in weathering of the body that causes physiological dysregulation and biological age being ...
Thorpe, Roland J., Kiefe, Catarina I., Forrester, Sarah N, Whitfield, Keith E.   +3 more
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Associations of biological aging with the morbidity and all-cause mortality of patients with lung cancer

Scientific Reports
Accelerated biological aging has been suggested to be an important risk factor for age-related diseases, but its role in the development of lung cancer is still unclear.
Qihang Xie, Haoran Qu, Siyu Xie, Wenhao Li, Rui Ouyang, Chengxiang Zhang, Ming Du   +6 more
doaj   +1 more source

[Bylaws of Coalition For Aging, LGBT- North Texas, Inc.]

, 2021
Bylaws of Coalition for Aging, LGBT- North Texas, Inc. documents from the Coalition for Aging LGBT Records (The Dallas Way)
Coalition for Aging, LGBT
core  

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Loneliness in Posttraumatic Stress Disorder: A Neglected Factor in Accelerated Aging?

Journal of Ageing and Longevity, 2022
Prior research suggests that people with Posttraumatic Stress Disorder (PTSD) may experience a form of accelerated biological aging. In other populations, loneliness has been shown to elevate risk for many of the same components of accelerated biological
Barton W. Palmer, Mariam A. Hussain, James B. Lohr   +2 more
doaj   +1 more source

The Impact of Witnessing Violence in the Context of Racism Among Black Americans: Depressive Symptoms and Accelerated Epigenetic Aging [PDF]

The current study examined the relationship between witnessing violence and racial discrimination on depressive symptoms and accelerated epigenetic aging in a non-treatment seeking sample of Black Americans.
Julian, Jacob
core   +1 more source