Results 101 to 110 of about 9,684,773 (259)
Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription
FEBS Open Bio, EarlyView.In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang +10 more
wiley +1 more source
FEBS Open Bio, EarlyView.Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo +4 more
wiley +1 more source
Correlating the accelerated test life of an automotive component with its field life
, 2004 Since new product designs have little field data available a correlation between field and accelerated test life cannot be made. However, a step partially accelerated life test approach where samples are tested under normal conditions for a time and then
Brutchen, George W.
core
Accelerated Life Testing to Predict Service Life and Reliability for an Appliance Door Hinge [PDF]
, 2015 Appliance manufacturers have traditionally performed physical testing using prototypes to assess reliability and service integrity of new product designs. However, for white goods where service lives are measured in years or decades, the use of endurance
Cheon, Seunghyeon +5 more
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Planning accelerated life tests with two or more experimental factors
, 1995 Accelerated life testing is a widely used tool for assessing the reliability of product components and materials. Most of the available literature on accelerated life testing deals with tests that use one accelerating factor and no other explanatory ...
Escobar, Luis A., Meeker, William Q.
core +1 more source
LubricantsRolling bearings serve as core rotating components in high-end equipment such as aerospace systems, wind turbines, and high-speed electric multiple units, and their service life directly affects the operational reliability and service life of the host ...
Xinmeng Song +4 more
doaj +1 more source
FEBS Open Bio, EarlyView.Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty +13 more
wiley +1 more source
Precast Concrete Elements for Accelerated Bridge Construction Final Report, Volume 1-1. Laboratory Testing of Precast Substructure Components: Boone County Bridge: TR-561, January 2009 [PDF]
, 2009 In July 2006, construction began on an accelerated bridge project in Boone County, Iowa that was composed of precast substructure elements and an innovative, precast deck panel system.
core
Alexandria Engineering JournalIn reliability engineering studies, the accelerated life tests with optimal test design that balances cost constraints is particularly important since the lifetimes of electro-mechanical, electronic, and mechanical goods are typically modelled with this ...
Haidy A. Newer +4 more
doaj +1 more source
FEBS Open Bio, EarlyView.Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia +9 more
wiley +1 more source