Mutations in ace2 gene modulate cytokine levels and alter immune responses in Mycobacterium tuberculosis and SARS-CoV-2 co-infection: a Cameroonian cohort [PDF]
Frontiers in ImmunologyIntroductionSARS-CoV-2 and Mycobacterium tuberculosis (Mtb) share similarities in their modes of transmission, pathophysiological symptoms, and clinical manifestations.
Mary Ngongang Kameni +20 more
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An overview of the gut side of the SARS-CoV-2 infection [PDF]
Intestinal Research, 2021 In late 2019, an outbreak of pneumonia caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) initiated in Wuhan, Hubei province, China. The major clinical symptoms described for coronavirus disease (COVID-19) include respiratory distress
Bruna Barbosa da Luz +8 more
doaj +1 more source
COVID-19 clinical implications: the significance of nanomedicine [PDF]
BioImpacts, 2020 COVID-19 pandemic has profoundly affected the lives of humans worldwide. We no longer experience the same quality of life and need to come up with effective solutions to combat the clinical implications.
Jaleh Barar
doaj +1 more source
SARS-CoV-2 and endothelial cell interaction in COVID-19: molecular perspectives
Vascular Biology, 2021 SARS-CoV-2 is the agent responsible for the coronavirus disease (COVID-19), which has been declared a pandemic by the World Health Organization. The clinical evolution of COVID-19 ranges from asymptomatic infection to death.
Roberta Giordo +3 more
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Bioinformatic Evaluation of the miRNAs Targeting ACE2 Gene in COVID-19 [PDF]
Disease and Diagnosis, 2021 Introduction: Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), which began in late 2019 in Wuhan, China, has become a global epidemic. Angiotensin 2 converting enzyme (ACE2) acts as a receptor for host function to cause acute coronavirus 2 acute ...
Milad Rafat +4 more
doaj +1 more source
Maternal Diet During Pregnancy and COVID-19 Susceptibility of Offspring: The “Thrifty Phenotype Hypothesis” Connection [PDF]
Journal of Tropical Life Science, 2021 There isaccumulating evidence suggesting that ACE2, the host cell receptor for the spike (S) protein of the SARS-CoV-2, mediates viral entry and infection, is under epigenetic control.
Custer C. Deocaris, Malona V. Alinsug
doaj +1 more source
Growing concerns on male reproductive health amidst COVID-19 pandemic
Journal of Family Medicine and Primary Care, 2022 Blood–testis barrier is body's innate mechanism to defend germ cells by creating a physical and immunological barrier. But some viral infections are known to evade it.
Megha Agrawal, Vikas Kumar, Gyan Vardhan
doaj +1 more source
Journal of Pure and Applied Microbiology, 2020 COVID-19 caused by SARS-CoV-2 has not only issued a pandemic situation but also lead to economic disaster and unprecedented health emergency. Being a close relative of Bat corona-virus, SARS and MERS it’s structural and sequence similarity has abled ...
Hiran Kanti Santra, Debdulal Banerjee
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Quantitative Interpretations of Energetic Features and Key Residues at SARS Coronavirus Spike Receptor-Binding Domain and ACE2 Receptor Interface [PDF]
Nanoscale, 2021, 2021 The wide spread of coronavirus disease 2019 (COVID-19) has declared a global health emergency. As one of the most important targets for antibody and drug developments, Spike RBD-ACE2 interface has received extensive attention. Here, using molecular dynamics simulations, we explicitly evaluated the binding energetic features of the RBD-ACE2 complex of ...
arxiv +1 more source
Viral pathogenesis of SARS-CoV-2 infection and male reproductive health [PDF]
Open Biology, 2021 Coronavirus disease 2019 (COVID-19) has emerged as a new public health crisis, threatening almost all aspects of human life. Originating in bats, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is transmitted to humans through unknown ...
Shubhadeep Roychoudhury +11 more
doaj +1 more source