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A perspective of precision medicine in the management of COVID-19 [PDF]

Novel Research in Microbiology Journal, 2021
The idea of precision medication is turning out progressively to be famous. The utilization of enormous information, genomics and other "omics" like metabolomics; proteomics and transcriptomics; could soon cause the fantasy of personalized medication ...
Shrikant Verma, Mohammad Abbas, Sushma Verma, Aliya Abbas Rizvi, Almas Khan, Syed Tasleem Raza, Farzana Mahdi   +6 more
doaj   +1 more source

COVID-19 and cardiovascular system—a comprehensive review [PDF]

Reviews in Cardiovascular Medicine, 2021
Coronavirus disease 2019 (COVID-19), a mystified cryptic virus has challenged the mankind that has brought life to a standstill. Catastrophic loss of life, perplexed healthcare system and the downfall of global economy are some of the outcomes of this
Ibrahim AlShahrani, Jagadish Hosmani, Vidya Gurram Shankar, Abdulaziz AlShahrani, Rafi Ahmad Togoo, Syed M Yassin, Shahrukh Khan, Shankargouda Patil   +7 more
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Secondary Publication: The Pathophysiology of COVID-19 (Coronavirus Disease 2019) Caused by the Infection of SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2)

Tokyo Women's Medical University Journal, 2021
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has a wide range of clinical manifestations, including acute respiratory distress syndrome, severe inflammation, abnormal blood coagulation, and ...
Ayako Nakamura-Ishizu, Fumio Nakamura
doaj   +1 more source

COVID-19: Time for a clinical classification?

Indian Journal of Pathology and Microbiology, 2022
COVID-19 pandemic caused by SARS-CoV-2 virus has been around for 2 years causing significant health-care catastrophes in most parts of the world. The understanding of COVID-19 continues to expand, with multiple newer developments such as the presence of ...
Dinesh Jothimani, Radhika Venugopal, Shruthi Manoharan, Silas Danielraj, Swetha Palanichamy, Gomathy Narasimhan, Ilankumaran Kaliamoorthy, Mohamed Rela   +7 more
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Molecular docking study and mapping the binding site of some antiviral nanobodies against receptor binding domain (RBD) of SARS-COV 2 [PDF]

Nanochemistry Research, 2021
Neutralization ability of some antiviral nanobodies was computed against the receptor binding domain (RBD) of the severe acute respiratory syndrome coronavirus 2 (SARS-COV 2).
zahra pahlavan, Mohammad Hossein Fatemi
doaj   +1 more source

Viral pathogenesis of SARS-CoV-2 infection and male reproductive health [PDF]

Open Biology, 2021
Coronavirus disease 2019 (COVID-19) has emerged as a new public health crisis, threatening almost all aspects of human life. Originating in bats, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is transmitted to humans through unknown ...
Shubhadeep Roychoudhury, Anandan Das, Niraj Kumar Jha, Kavindra Kumar Kesari, Shatabhisha Roychoudhury, Saurabh Kumar Jha, Raghavender Kosgi, Arun Paul Choudhury, Norbert Lukac, Nithar Ranjan Madhu, Dhruv Kumar, Petr Slama   +11 more
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Deep Mutational Scanning of SARS-CoV-2 Receptor Binding Domain Reveals Constraints on Folding and ACE2 Binding

Cell, 2020
The receptor binding domain (RBD) of the SARS-CoV-2 spike glycoprotein mediates viral attachment to ACE2 receptor, and is a major determinant of host range and a dominant target of neutralizing antibodies.
Tyler N. Starr, Allison J. Greaney, Allison J. Greaney, Sarah K. Hilton, Sarah K. Hilton, Daniel Ellis, K. H. Crawford, K. H. Crawford, A. Dingens, M. Navarro, John E. Bowen, M. A. Tortorici, A. Walls, N. King, D. Veesler, Jesse D. Bloom, Jesse D. Bloom, Jesse D. Bloom   +17 more
semanticscholar   +2 more sources

Are new genome variants detected in SARS-CoV-2 expected considering population dynamics in viruses?

The EuroBiotech Journal, 2021
The pandemic COVID-19 is caused by a highly transmissible severe acute respiratory coronavirus 2 (SARS-CoV-2) which showed the highest morbidity and mortality rates among the other coronavirus infections such as SARS-CoV and MERS-CoV.
Ergoren Mahmut Cerkez, Tulay Pinar, Dundar Munis   +2 more
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Structural basis for the recognition of SARS-CoV-2 by full-length human ACE2

Science, 2020
How SARS-CoV-2 binds to human cells Scientists are racing to learn the secrets of severe acute respiratory syndrome–coronavirus 2 (SARS-CoV-2), which is the cause of the pandemic disease COVID-19. The first step in viral entry is the binding of the viral
R. Yan, Yuanyuan Zhang, Yaning Li, L. Xia, Yingying Guo, Qiang Zhou   +5 more
semanticscholar   +1 more source

The therapeutic potential of the novel angiotensin-converting enzyme 2 in the treatment of coronavirus disease-19 [PDF]

Veterinary World, 2021
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the etiological agent of coronavirus disease 2019 (COVID-19). This virus has become a global pandemic with unprecedented mortality and morbidity along with attendant financial and economic ...
Ademola Adetokunbo Oyagbemi, Temitayo Olabisi Ajibade, Yapo Guillaume Aboua, Idayat Titilayo Gbadamosi, Aduragbenro Deborah A. Adedapo, Abimbola Obemisola Aro, Olumuyiwa Abiola Adejumobi, Emma Thamahane-Katengua, Temidayo Olutayo Omobowale, Olufunke Olubunmi Falayi, Taiwo Olaide Oyagbemi, Blessing Seun Ogunpolu, Fasilat Oluwakemi Hassan, Iyanuoluwa Omolola Ogunmiluyi, Olufunke Eunice Ola-Davies, Adebowale Benard Saba, Adeolu Alex Adedapo, Sanah Malomile Nkadimeng, Lyndy Joy McGaw, Prudence Ngalula Kayoka-Kabongo, Momoh Audu Yakubu, Oluwafemi Omoniyi Oguntibeju   +21 more
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