Results 31 to 40 of about 620,051 (294)

Role of angiotensin-converting enzyme in myeloid cell immune responses

open access: yesCellular & Molecular Biology Letters, 2020
Angiotensin-converting enzyme (ACE), a dicarboxypeptidase, plays a major role in the regulation of blood pressure by cleaving angiotensin I into angiotensin II (Ang II), a potent vasoconstrictor.
Duo-Yao Cao   +7 more
doaj   +1 more source

High Sodium Intake Strengthens the Association of ACE I/D Polymorphism with Blood Pressure in a Community [PDF]

open access: yes, 2007
BackgroundLimited evidence is available on a gene–environment interaction of angiotensin-converting enzyme (ACE) gene I/D polymorphism and high blood pressure (BP) with salt intake among general populations. We hypothesized that persons with the I allele
Cui Renzhe   +9 more
core   +1 more source

Pulmonary midkine inhibition ameliorates sepsis induced lung injury

open access: yesJournal of Translational Medicine, 2021
Background Midkine is a multi-functional molecule participating in a various key pathological process. We aimed to evaluate the change of midkine in sepsis and its association with angiotensin-converting enzyme (ACE) system, as well as the mechanism by ...
Jing-Yuan Xu   +4 more
doaj   +1 more source

Annihilator Banach ∗-algebras and the Peter-Weyl theorem [PDF]

open access: yes, 1976
The QUO VADIS (the effects of QUinapril On Vascular Ace and Determinants of ISchemia) study was a randomized, double-blind, placebo-controlled trial designed to evaluate the effects of long-term angiotensin-converting enzyme (ACE) inhibition on ...
Dennis Wildfogel   +15 more
core   +2 more sources

POLYMORPHISM IN THE ANGIOTENSIN-CONVERTING ENZYME (ACE) GENE AND ACE ACTIVITY IN TYPE 2 DIABETIC PATIENTS [PDF]

open access: yesActa Medica Iranica, 2008
"nDiabetes mellitus is a multifactorial disease. It has recently been shown that an insertion (I)/deletion (D) polymorphism exists in the angiotensin-converting enzyme (ACE) gene that can affect the serum ACE level. There are three genotypes: DD, DI,
A Nikzamir   +4 more
doaj   +2 more sources

New perspectives in the renin-angiotensin-aldosterone system (RAAS) III: endogenous inhibition of angiotensin converting enzyme (ACE) provides protection against cardiovascular diseases.

open access: yesPLoS ONE, 2014
ACE inhibitor drugs decrease mortality by up to one-fifth in cardiovascular patients. Surprisingly, there are reports dating back to 1979 suggesting the existence of endogenous ACE inhibitors.
Miklós Fagyas   +8 more
doaj   +1 more source

The Angiotensin Converting Enzyme Insertion/Deletion Polymorphism Modifies Exercise-Induced Muscle Metabolism. [PDF]

open access: yesPLoS ONE, 2016
OBJECTIVE:A silencer region (I-allele) within intron 16 of the gene for the regulator of vascular perfusion, angiotensin-converting enzyme (ACE), is implicated in phenotypic variation of aerobic fitness and the development of type II diabetes.
David Vaughan   +9 more
doaj   +1 more source

A Quality Improvement Initiative to Standardize Pneumocystis jirovecii Pneumonia Prophylaxis in Pediatric Patients With Solid Tumors

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Pediatric patients with extracranial solid tumors (ST) receiving chemotherapy are at an increased risk for Pneumocystis jirovecii pneumonia (PJP). However, evidence guiding prophylaxis practices in this population is limited. A PJP‐related fatality at our institution highlighted inconsistent prescribing approaches and concerns about
Kriti Kumar   +8 more
wiley   +1 more source

Bi-directional actions of estrogen on the renin-angiotensin system

open access: yesBrazilian Journal of Medical and Biological Research, 1999
Estrogen stimulates the renin-angiotensin system by augmenting both tissue and circulating levels of angiotensinogen and renin. We show, however, that angiotensin converting enzyme (ACE) activity in the circulation and in tissues is reduced in two animal
K.B. Brosnihan   +3 more
doaj   +1 more source

Sickle Cell Disease Is an Inherent Risk for Asthma in a Sibling Comparison Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Sickle cell disease (SCD) and asthma share a complex relationship. Although estimates vary, asthma prevalence in children with SCD is believed to be comparable to or higher than the general population. Determining whether SCD confers an increased risk for asthma remains challenging due to overlapping symptoms and the ...
Suhei C. Zuleta De Bernardis   +9 more
wiley   +1 more source

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