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Flavonoids-Rich Orthosiphon stamineus Extract as New Candidate for Angiotensin I-Converting Enzyme Inhibition: A Molecular Docking Study [PDF]

open access: yesMolecules, 2016
This study aims to evaluate the in vitro angiotensin-converting enzyme (ACE) inhibition activity of different extracts of Orthosiphon stamineus (OS) leaves and their main flavonoids, namely rosmarinic acid (RA), sinensetin (SIN), eupatorin (EUP) and 3 ...
Armaghan Shafaei   +6 more
doaj   +4 more sources

Albumin-Bound Fatty Acids Modulate Endogenous Angiotensin-Converting Enzyme (ACE) Inhibition [PDF]

open access: yesBiomedicines
Background/Objectives: Human serum albumin (HSA) is a major endogenous inhibitor of angiotensin-converting enzyme (ACE) and helps fine-tune the activity of the renin–angiotensin–aldosterone system (RAAS), thereby potentially influencing the development ...
Enikő Edit Enyedi   +9 more
doaj   +2 more sources

Development of a Spectrophotometric Method for Monitoring Angiotensin-Converting Enzyme in Dairy Products [PDF]

open access: yesPakistan Veterinary Journal, 2013
The angiotensin-converting enzyme (ACE) regulates the levels of blood pressure through generation of angiotensin-II from angiotensin-I. It is of great importance to have a reliable and yet simple method for a quantitative determination ACE inhibitory ...
Julijana Tomovska*, S. Presilski, N. Gjorgievski, N. Tomovska1, M. S. Qureshi2 and N. P. Bozinovska3
doaj   +2 more sources

Blood Pressure Regulating and Antioxidant Potentials of Theobroma Cacao Pod Husk Protein Hydrolysates [PDF]

open access: yesAvicenna Journal of Medical Biochemistry, 2021
Background: Agrowastes like Theobroma cacao (Cocoa) pod husk can be used to prepare bioactive peptides with various bio-functionalities. Objectives: This study aimed to investigate antioxidant and angiotensin converting enzyme I (ACE) inhibitory ...
Rotimi Arise   +2 more
doaj   +1 more source

Learning and Investigation of the Role of Angiotensin-Converting Enzyme in Radiotherapy for Nasopharyngeal Carcinoma

open access: yesBiomedicines, 2023
Ionizing radiation (IR) is an important treatment for nasopharyngeal carcinoma (NPC) that mainly kills tumor cells by producing large amounts of reactive oxygen species (ROS). Intracellular ROS levels affect the sensitivity of tumor cells to IR. Recently,
Yanan Ding   +9 more
doaj   +1 more source

Ultrasonic Pre-treatment for the Preparation of ACE-inhibitory Peptides from the Tea Residue Protein through Enzymatic Hydrolysis and Its Stability

open access: yesShipin gongye ke-ji, 2022
Angiotensin-converting enzyme (ACE) plays an important role in blood pressure regulation, and inhibition of its activity is beneficial to maintain blood pressure balance.
Cheng DAI   +5 more
doaj   +1 more source

Identification of a Novel ACE-inhibitory Peptide from Sheep Casein and Evaluation of the Molecular Binding Mechanism

open access: yesShipin gongye ke-ji, 2022
The purpose of this study was to prepare a novel Angiotensin-I-Converting Enzyme(ACE) inhibitory peptide by hydrolyzing sheep casein with protease and analyze its molecular inhibitory mechanism, so as to provide technical support for the development of ...
Haixia TANG   +5 more
doaj   +1 more source

Screening, Probiotic Properties Evaluation and Application of ACE-inhibitory Peptide-producing Lactic Acid Bacteria

open access: yesShipin gongye ke-ji, 2022
Objectives: To screen lactic acid bacteria (LAB) produced angiotensin-converting enzyme (ACE) inhibitory peptides and to evaluate their probiotic properties.
Xiaoling SONG   +4 more
doaj   +1 more source

Novel angiotensin-converting enzyme and pancreatic lipase oligopeptide inhibitors from fermented rice bran

open access: yesFrontiers in Nutrition, 2022
This study determined the inhibitory activity of oligopeptides against angiotensin-converting enzyme (ACE) and pancreatic lipase through in vitro tests, molecular docking, and enzyme inhibition.
Jingfei Hu   +23 more
doaj   +1 more source

Formation and inhibition mechanism of novel angiotensin I converting enzyme inhibitory peptides from Chouguiyu

open access: yesFrontiers in Nutrition, 2022
Angiotensin I converting enzyme (ACE) inhibitory peptides from fermented foods exhibit great potential to alleviate hypertension. In this study, the peptide extract from Chouguiyu exhibited a good inhibition effect on ACE, and the inhibition rate was ...
Daqiao Yang   +17 more
doaj   +1 more source

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