Predicting drug metabolism: Concepts and challenges [PDF]
The paper begins with a discussion of the needs and goals of metabolic predictions in early drug research. Major difficulties toward this objective are examined, mainly the various substrate and product selectivities characteristic of drug metabolism. In
Balmat, A.-L, Long, Anthony, Testa, B.
core
Long-term anticoagulant effects of CYP2C9 and VKORC1 genotypes in phenprocoumon users [PDF]
Boer, A.C. (Anton) de +4 more
core +1 more source
Leukocytoclastic Vasculitis Associated with Coumarin Derivatives: A Case Report. [PDF]
Mahadevappa M +3 more
europepmc +1 more source
Personalized management of acenocoumarol dosage using eGFR: Analysis of INR data in a cohort of 204 patients. [PDF]
Farandzha D, Velchev V, Hazarbasanov D.
europepmc +1 more source
Leu208Val and Ile181Leu variants of cytochrome P450 CYP2C9 are not related to the acenocoumarol dose requirement in a Spanish population [PDF]
Alberca, I. (Ignacio) +5 more
core +1 more source
Anticoagulation Therapy in Advanced Chronic Kidney Disease: Balancing Bleeding and Thromboembolic Risk. [PDF]
Suliman IL +16 more
europepmc +1 more source
Electro-encephalographic surrogate measures fail to describe the pharmacodynamic interaction between ketamine and propofol. [PDF]
Mortier, Eric +2 more
core +1 more source
Comparative Outcomes of Apixaban and Acenocoumarol in Advanced Chronic Kidney Disease and Atrial Fibrillation: A Retrospective Observational Study. [PDF]
Suliman IL +12 more
europepmc +1 more source
Menstrual disturbances in women with advanced heart failure and heart transplant recipients. [PDF]
Fernández Villa N +6 more
europepmc +1 more source

