Results 31 to 40 of about 1,092,827 (257)

Mechanism of persistence of indigenous bifidobacteria under the impact of acetate in the human colon biotope

Журнал микробиологии, эпидемиологии и иммунобиологии, 2021
Aim. To determine the role of the acetate in the persistence of indigenous bifidobacteria in the colon biotope through the lysozyme resistance in model conditions of the acetylation–deacetylation of peptidoglycan.Materials and methods.
O. V. Bukharin, S. V. Andryuschenko, N. B. Perunova, E. V. Ivanova   +3 more
doaj   +1 more source

Metabolite Profiling of Osteoporosis and Atherosclerosis in Postmenopausal Women: A Cross-Sectional Study

Vascular Health and Risk Management, 2020
Miika Värri,1 Leo Niskanen,2 Tomi-Pekka Tuomainen,3 Risto Honkanen,1,4 Heikki Kröger,1,5 Marjo T Tuppurainen1,6 1Kuopio Musculoskeletal Research Unit (KMRU), Surgery, Institute of Clinical Medicine, University of Eastern Finland, Kuopio ...
Värri M, Niskanen L, Tuomainen TP, Honkanen R, Kröger H, Tuppurainen MT   +5 more
doaj  

An Infant Milk Formula Supplemented with Heat-Treated Probiotic Bifidobacterium animalis subsp. lactis CECT 8145, Reduces Fat Deposition in C. elegans and Augments Acetate and Lactate in a Fermented Infant Slurry

Foods, 2020
Pediatric obesity has a growing health and socio-economical impact due to cardiovascular and metabolic complications in adult life. Some recent studies suggest that live or heat-treated probiotics have beneficial effects in preventing fat deposition and ...
Ángela Silva, Nuria Gonzalez, Ana Terrén, Antonio García, Juan Francisco Martinez-Blanch, Vanessa Illescas, Javier Morales, Marcos Maroto, Salvador Genovés, Daniel Ramón, Patricia Martorell, Empar Chenoll   +11 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Bifidobacterium dentium Fortifies the Intestinal Mucus Layer via Autophagy and Calcium Signaling Pathways

mBio, 2019
Much remains unknown about how the intestinal microbiome interfaces with the protective intestinal mucus layer. Bifidobacterium species colonize the intestinal mucus layer and can modulate mucus production by goblet cells. However, select Bifidobacterium
Melinda A. Engevik, Berkley Luk, Alexandra L. Chang-Graham, Anne Hall, Beatrice Herrmann, Wenly Ruan, Bradley T. Endres, Zhongcheng Shi, Kevin W. Garey, Joseph M. Hyser, James Versalovic   +10 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Short-Chain Fatty Acids Differentially Affect Intracellular Lipolysis in a Human White Adipocyte Model

Frontiers in Endocrinology, 2018
Background and aimsGut-derived short-chain fatty acids (SCFA), formed by microbial fermentation of dietary fibers, are believed to be involved in the etiology of obesity and diabetes.
Johan W. E. Jocken, Johan W. E. Jocken, Manuel A. González Hernández, Nicole T. H. Hoebers, Christina M. van der Beek, Christina M. van der Beek, Yvonne P. G. Essers, Ellen E. Blaak, Ellen E. Blaak, Emanuel E. Canfora, Emanuel E. Canfora   +10 more
doaj   +1 more source

Synthesis and crystal structure of one new Pb(II) complex constructed by 1,10-phenanthroline and two carboxylate ligands

Main Group Metal Chemistry, 2021
The complex [Pb(phen)(4-NB)(CH3COO)] of lead(II) was prepared and characterized by means of elemental analysis, FT-IR, and single crystal X-ray analysis, where phen = 1,10-phenanthroline, 4-NB = 4-nitrobenzoate.
Zhang Lu-Lin, Tang Shi-Li, Li De-Jun, Cheng Yuan-Zheng, Zhang Li-Ping   +4 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Acetate induces growth arrest in colon cancer cells through modulation of mitochondrial function [PDF]

, 2021
Acetate is one of the main short chain fatty acids produced in the colon when fermentable carbohydrates are digested. It has been shown to affect normal metabolism, modulating mitochondrial function and fatty acid oxidation.
Sahuri Arisoylu, M., Shinjyo, N., Nunn, A., Thomas, E.L., Mould, R., Guy, G., Bell, J.D., Bligh, S.W.A.   +7 more
core   +1 more source