Results 151 to 160 of about 250,937 (292)

Making sense of cardiomyopathy caused by deletion of acetyl-CoA carboxylase 1 and 2. Reply. [PDF]

J Clin Invest
Kim CW, Mitsche MA, Horton JD.
europepmc   +1 more source

Inherited metabolic epilepsies–established diseases, new approaches

Epilepsia Open, EarlyView.
Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley   +1 more source

Making sense of cardiomyopathy caused by deletion of acetyl-CoA carboxylase 1 and 2. [PDF]

J Clin Invest
Tian R, Lewandowski ED.
europepmc   +1 more source

Ketogenic diet for infantile epileptic spasms

Epilepsia Open, EarlyView.
Abstract Approximately half of all cases of Infantile Epileptic Spasms Syndrome (IESS) do not respond to vigabatrin and hormonal therapies. There is no clear consensus as to the second‐line therapy for IESS. Ketogenic diet (KD) has emerged as an effective treatment for certain drug‐resistant epilepsies and in many cases of IESS.
Morris H. Scantlebury, Anamika Choudhary, Andy Cheuk‐Him Ng, Cezar Gavrilovici   +3 more
wiley   +1 more source

Cytosolic acetyl-CoA: a metabolic regulator of mitophagy. [PDF]

Life Metab
Xiong J.
europepmc   +1 more source

Light‐Driven Butyrate Production by a Probiotic Clostridium tyrobutyricum Enabled by a Cell‐Semiconductor Hybrid Interface

Food Chemistry International, EarlyView.
This schematic illustrates a light‐driven biohybrid system where CdS nanoparticles, mineralized on the probiotic Clostridium tyrobutyricum, inject photoelectrons to elevate intracellular NADH. This boosts the flux through key NADH‐dependent enzymes (GapA, Hbd, and Bcd), reprogramming metabolism to enhance butyrate yield by 33.2% and selectivity to 95.7%
Qianru Zhao, Zhihan Yang, Bowen Shen, Ling Jiang   +3 more
wiley   +1 more source

Optimization of Antifungal 1,5-Diaryl-Pyrazole Acetyl-CoA Synthetase Inhibitors. [PDF]

ACS Omega
Propp JP, Ferreira JC, Enayati P, Alden KM, Daraji DG, Lail CL, Heene ME, Jezewski AJ, Wakade R, Castor D, Williams NS, Hagen TJ, Krysan DJ.   +12 more
europepmc   +1 more source

Influence of Acetyl-CoA Metabolism in Histone Acetylation and Cancer

, 2017
Cancer cells increase nutrient uptake to support viability and proliferation. The influx of nutrients alters intermediary metabolite levels, and compelling evidence shows that metabolite availability impacts cell functions through altering chromatin ...
Lee, Joyce V
core  

Phytochemistry, Chemotypic Diversity and Antimicrobial Potential of Essential Oils From Native Aromatic Plants of the Americas: A Systematic Review

Flavour and Fragrance Journal, EarlyView.
This review bridges ancestral indigenous knowledge with modern pharmacology, summarizing the phytochemistry and antimicrobial properties of essential oils from seven native American species. It highlights their significant activity against bacterial, fungal and parasitic pathogens, emphasizing their potential as sustainable therapeutic and agricultural
Arley Rey Páez, Mozaniel Santana de Oliveira, João Paulo Viana Leite   +2 more
wiley   +1 more source

AcuB senses cellular energy charge to coordinate acetyl-CoA synthesis in bacteria. [PDF]

Nat Commun
Janetzky M, Geist N, Schulze S, Rückert H, Gatzemeyer K, Palm GJ, Berndt L, Girbardt B, Weis D, Menyes I, Welsch N, Schweder T, Dörr M, Kemnitz S, Bornscheuer UT, Delcea M, Lammers M.   +16 more
europepmc   +1 more source