Results 171 to 180 of about 250,937 (292)

Acetyl-CoA carboxylase maintains energetic balance for functional oogenesis. [PDF]

Nat Commun
Amartuvshin O, Lin CH, Ke YT, Lee HJ, Kajal K, Huang TL, Wang WD, Lu TM, Yih LH, Tseng CY, Hsu HJ.   +10 more
europepmc   +1 more source

[4] Acetyl-CoA carboxylase from yeast [PDF]

, 1981
openaire   +2 more sources

Adss1–HDAC3 Interaction: A Novel Mechanism for Epigenetic Regulation of Metabolism in Adipose Tissue

iNew Medicine, EarlyView.
ABSTRACT Obesity and its related metabolic disorders have emerged as global public health challenges with underlying mechanisms involving an imbalance between energy storage and expenditure in the adipose tissue. In recent years, with the deepening research on adipose tissue metabolism, the cross talk between metabolic enzymes and epigenetic regulation
Jiarui Zhao, Jingjing Sun, Yan Lu, Ying Yang   +3 more
wiley   +1 more source

ATP Citrate Lyase in Metabolic Disease: Mechanistic Insights and Clinical Potential

iNew Medicine, EarlyView.
ATP citrate lyase (ACLY) is a central metabolic hub that diverts mitochondrial citrate to fuel de novo lipogenesis, cholesterol biosynthesis, and protein acetylation. Given its robust correlation with pathological changes in multiple human diseases, ACLY inhibitors featuring distinct pharmacological strengths have been developed for therapeutic ...
Wenbiao Wang, Xinyan Li, Honglu Shi, Gaolei Song, Zhifu Xie, Jingya Li   +5 more
wiley   +1 more source

ACSS2 involved in acetyl-CoA synthesis regulates skeletal muscle function. [PDF]

FEBS Lett
Gunasekaran M, Campos G, Wells NM, Lambuu K, Draper I, Pacak CA, Kang PB.   +6 more
europepmc   +1 more source

Mode‐of‐Action and Human Relevance Assessment for Diisononyl Phthalate‐Induced Liver Tumors in Rodents

Journal of Applied Toxicology, EarlyView.
ABSTRACT Diisononyl phthalate (DINP) is a high molecular weight phthalate and high production volume chemical. DINP's carcinogenic potential has been investigated in four rodent bioassays, with liver tumors observed in three of the studies. Authoritative assessments have hypothesized that DINP acts through the peroxisome proliferator‐activated receptor
Amanda N. Buerger, Melissa M. Heintz, Laurie C. Haws, Chad M. Thompson   +3 more
wiley   +1 more source

Bisphenol A and Its Analogs: Toxicity Analysis in Mouse and Rat Liver—A Review

Journal of Applied Toxicology, EarlyView.
ABSTRACT Bisphenol A (BPA) and its analogs are widely recognized for their use in industry and plastic manufacturing. Consequently, humans and animals are continually exposed to various substances in their daily lives. This review evaluates the hepatic toxicity of BPA and its analogs in mice and rats, with particular emphasis on molecular mechanisms ...
Sevda Bagdatli, Muhammed Canik, Gizem Gencay, Nurbanu Zengin, Tarık Dinc, Nazan Deniz Yön   +5 more
wiley   +1 more source

A Deep Learning Framework for the Discovery of Natural-Product Candidate Binders of Acetyl-CoA Carboxylase 2 (ACC2) with Potential Relevance to Cardiometabolic Lipid Metabolism. [PDF]

Pharmaceuticals (Basel)
Alzunaidy NA.
europepmc   +1 more source

Perspectives of High‐Resolution Mass Spectrometry in Soil Science

Journal of Plant Nutrition and Soil Science, EarlyView.
ABSTRACT Soil biogeochemical research requires specific, sensitive, and accurate methods to identify and quantify organic molecules in order to trace biochemical processes and assess element cycling in complex, heterogenous systems. High‐resolution mass spectrometry (HRMS) has evolved into a transformative tool for unraveling the complex chemical ...
Bruno Glaser, Tobias Bromm, Klaus Kaiser, Arthur Gross, Carsten Simon, Snežana Maletić, Ines Mulder, Oliver J. Lechtenfeld, Sören Thiele‐Bruhn, Ivy Notterpek, Callum Banfield, Michaela A. Dippold   +11 more
wiley   +1 more source

Mitochondrial acetyl-CoA reprogramming by the SIRT3-ACSS2-OPA1 axis confers resistance to ferroptosis in Parkinson's disease. [PDF]

Redox Biol
Ding XS, Wang B, Han Z, Feng CX, Li YN, Wang YF, Guru JC, Cao J, Zhang RL, Wang XL, Yang Q, Qu Y, Gao L.   +12 more
europepmc   +1 more source