Anticancer potential of berberine: Molecular pathways and current clinical trial perspectives
Abstract Cancer is constantly rising mortality rates due to its late prognosis, poor management, and expensive treatment. Multi‐sectoral approaches for cancer management include hygienic practices, synthetic drug exploitation, radiation therapy, and diet modifications.
Muhammad Maaz +10 more
wiley +1 more source
Discovery and mechanism of a highly selective, antifungal acetyl-CoA synthetase inhibitor. [PDF]
Jezewski AJ +14 more
europepmc +1 more source
Abstract The dietary and lifestyle practices have predominantly compromised human health, which are influenced by modernization and industrialization. Hypercholesterolemia, caused by the consumption of fatty and fried foods and a sedentary lifestyle, is a major modifiable risk factor for cardiovascular disease and commonly coexists with obesity ...
Muhammad Usman Khalid +8 more
wiley +1 more source
Enhancing Nonylphenol Biodegradation: The Role of Acetyl-CoA C-Acetyltransferase in <i>Bacillus cereus</i>. [PDF]
Lu F, Luo D, Yang L, Dong R.
europepmc +1 more source
myo‐Inositol's role in laying hens’ active gastrointestinal microbiota: a strain comparison
Abstract BACKGROUND myo‐Inositol (MI) is a cyclitol involved in cellular metabolism and phytate degradation, yet its influence on the gastrointestinal tract (GIT) microbiota of laying hens remains poorly understood. This study investigated the effects of graded dietary MI supplementation on the active GIT microbial communities of two commercial laying ...
Naomi Sarpong +4 more
wiley +1 more source
Sphingosine kinase-2 inhibition promotes immunogenic differentiation of myeloid-derived suppressor cells through an Acetyl-CoA carboxylase-phosphatidylcholine axis. [PDF]
Chakraborty P +28 more
europepmc +1 more source
ABSTRACT To address the widespread constraints imposed by saline‐alkaline soils on agricultural production worldwide, the combined reclamation and carbon cycle regulation effects of artificial humic acid (AHA) and a multifunctional microbial inoculant were evaluated through pot experiments. Results demonstrated that co‐application of AHA (4 g·kg−1) and
Ying Zhao +4 more
wiley +1 more source
Mechanistic insights into the acetyl-CoA recognition by SLC33A1. [PDF]
Zhou D +4 more
europepmc +1 more source
The experimental design and the exometabolomic findings obtained by 1H‐NMR analysis of conditioned media from subcutaneous (SAT) and epididymal adipose tissue (EAT) explants of control and obese mice supplemented with chia oil (1.5% (w/w)). Following 8 weeks of control or high‐fat diet and 5 weeks of chia oil supplementation, SAT and EAT explants were ...
Gilson Costa dos Santos Jr +5 more
wiley +1 more source
YhcB mediates growth-phase control of fatty acid biosynthesis through regulation of acetyl-CoA carboxylase. [PDF]
Stanley HM, Trent MS.
europepmc +1 more source

