Results 201 to 210 of about 214,689 (295)

Interplay of Ser273 Phosphorylation and K268 and K293 Acetylation in PPARγ: Implications for PPARγ Activation

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Post‐translational modifications (PTMs) play a critical role in regulating the transcriptional activity of PPARγ, a nuclear receptor central to glucose and lipid homeostasis. Among these, lysine acetylation at K268 and K293 and phosphorylation at S273 are particularly relevant to insulin sensitivity.
Caique Camargo Malospirito, Marieli Mariano Gonçalves Dias, Gabriel Ernesto Jara, Thayná Mendonça Avelino, Giovanna Blazutti Elias, Paulo Sergio Lopes de Oliveira, Ana Carolina Migliorini Figueira   +6 more
wiley   +1 more source

Divergent acetyl-CoA binding modes mediate allosteric inhibition of bacterial hybrid-type malic enzymes. [PDF]

J Biol Chem
Sassa M, Yamato H, Tanino H, Fukuda Y, Inoue T.   +4 more
europepmc   +1 more source

Universal and Lineage‐Specific Patterns in the Distribution of ECOD Domain Homology Groups Across Superkingdoms

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Proteins are built from modular domains that serve as fundamental units of structure and evolution. While individual domains have been extensively cataloged, their collective distribution across the lineages of life has remained poorly resolved.
Rui Guo, Jimin Pei, Jing Zhang, Qian Cong, Nick V. Grishin, R. Dustin Schaeffer   +5 more
wiley   +1 more source

Inactivation of Acetyl-CoA Acyltransferase 1 enhances the proliferation and motility of nasopharyngeal carcinoma cells. [PDF]

Mol Cell Oncol
Wei W, Li L, Zhao W, Zheng S, Zhou X, Liang H, Wang W, He F, Liang Y, Huang G, Zhang Z, Xiao X.   +11 more
europepmc   +1 more source

First genome sequence of a European Alternaria brassicae isolate and genes involved in early development of alternaria leaf spot on Brassica juncea

Pest Management Science, EarlyView.
This article reports the first genome sequence of a UK Alternaria brassicae isolate. Dual RNA‐sequencing profiling of A. brassicae‐infected Brassica juncea leaves identified differentially expressed genes involved in pathogenicity and host response pathways in moderately resistant Sej‐2 (2) and moderately susceptible Pusa Jaikisan cultivars.
Kevin M. King, Graham McLaughlin, Chinthani S. Karandeni Dewage, Zedi Gao, David J. Hughes, Jonathan S. West, Henrik U. Stotz   +6 more
wiley   +1 more source

Pharmacological induction of acetyl-CoA carboxylase 1 autophagic degradation attenuates lipid accumulation and cholangiocarcinoma progression. [PDF]

J Exp Clin Cancer Res
Pan Y, Zhang N, Fu X, Wang X, Ma Y, Chen Q, Zhou Y, Liu H, Zhu Y, Xu L, Wang Q, Chen D, Wang Z, Wang L.   +13 more
europepmc   +1 more source

A Trp574–Leu substitution confers resistance to three classes of acetolactate synthase inhibitors in Australian brome grass (Bromus diandrus)

Pest Management Science, EarlyView.
Target‐site based imidazolinone resistance in brome grass was found to be conferred by a mutation at position 574 in the ALS gene and to severely impact the efficacy of the herbicide Intervix®, a co‐formulation of imazamox and imazapyr. Abstract BACKGROUND Brome grass (Bromus diandrus) is a prevalent weed in southern Australian cropping regions which ...
Roberto Busi, Danica Goggin, Nick Eyres, Fabian Runge, Aimone Porri, Ken Flower   +5 more
wiley   +1 more source

Acetyl-CoA carboxylase 1 knockdown promotes esophageal squamous cell carcinoma metastasis via the CXCL8-NET axis. [PDF]

Commun Biol
Tang J, Qi B, Zhuo Q, Huo S, Dang X, Pang T, Cao K, Liu Y, Zhao B.   +8 more
europepmc   +1 more source

Essential oils as bioherbicides: effects of orange and citronella oils on weed germination and early growth

Pest Management Science, EarlyView.
Essential oils from orange and citronella showed dose‐dependent inhibition of weed germination and early growth, highlighting their potential as bioherbicides and sustainable tools for integrated weed management. Abstract BACKGROUND Increasing selection of herbicide‐resistant weed biotypes has intensified the search for alternatives to the intensive ...
Geovana Rocha Marzochi, Leonardo de Oliveira Semensato, Francielli Santos de Oliveira, Virginia Claudia Paulino Silva, Eliane Gomes Fabri, Evandro Henrique Schinor, Andréia Cristina Silva Hirata, Moacir Rossi Forim, Angélica Correa Kauffmann, Patricia Andrea Monquero   +9 more
wiley   +1 more source

An alternative route for β-hydroxybutyrate metabolism supports cytosolic acetyl-CoA synthesis in cancer cells. [PDF]

Nat Metab
Kaluba FC, Rogers TJ, Jeong YJ, House R'J, Waldhart A, Sokol KH, Daniels SR, Lee CJ, Longo J, Johnson A, Sartori VJ, Sheldon RD, Jones RG, Lien EC.   +13 more
europepmc   +1 more source