Results 201 to 210 of about 172,172 (296)

The mechanism of acetyl-CoA synthase through the lens of a nickel model system. [PDF]

Nat Commun
Nath S, Griego L, Mirica LM.
europepmc   +1 more source

Harnessing energy metabolism for enhanced bone defect repair: Mechanisms and therapeutic strategies

VIEW, EarlyView.
This review addresses the critical challenge of bone defect repair by focusing on the underexplored role of cellular energy metabolism. It synthesizes regulatory mechanisms in bone‐forming cells and sums up innovative strategies—leveraging cell derivatives, active factors, and biomimetic scaffolds—to modulate metabolism for enhanced regeneration.
Junting Li, Yulan Liu, Yuran Li, Yingjie Hua, Xinquan Jiang, Mingliang Zhou   +5 more
wiley   +1 more source

Isotype-selective roles of hepatic acetyl-CoA carboxylases in a mouse model of fatty liver disease. [PDF]

Mol Metab
Beretta M, Vancuylenburg CS, Shrestha R, Olzomer EM, Osborne B, Zhou M, Zhang S, Hargreaves A, Byrne FL, Hoehn KL.   +9 more
europepmc   +1 more source

CRISPR/Cas9 Genome Engineering in Non‐Conventional Oleaginous Yeasts: Applications, Challenges, and Prospects

Yeast, EarlyView.
ABSTRACT Given the biotechnological potential of yeast‐derived oils for oleochemical production, genes encoding lipid metabolism enzymes are key targets for metabolic engineering. Genetic engineering tools such as Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/Cas9, Transcription Activator‐Like Effector Nucleases (TALENs), Zinc ...
Rodrigo Gonçalves Dias, Fernanda Pinheiro Moreira Freitas, Eduardo Luís Menezes de Almeida, Luciano Gomes Fietto, Agustin Zsögön, Wendel Batista da Silveira   +5 more
wiley   +1 more source

PII interactions with the acetyl-CoA carboxylase subunits BADC and BCCP co-regulate lipid and nitrogen metabolism in Arabidopsis. [PDF]

Plant Physiol
Garneau MG, Jorge GL, Shockey J, Thelen JJ, Bates PD.   +4 more
europepmc   +1 more source

Silencing of juvenile hormone‐related genes through RNA interference leads to molt failure and high mortality in the spongy moth

Insect Science, EarlyView.
The feasibility of using RNA interference to control the globally important quarantine pest, the spongy moth. Targeting genes related to JHs play an important role in the growth and development of insects. First, the open reading frames (ORFs) of Ldjhamt and Ldjheh were identified and characterized, and the target genes were cloned and double‐stranded ...
Wenzhuai Ji, Qing Xie, Xiaoxiao Chang, Juan Shi   +3 more
wiley   +1 more source

A genetically encoded fluorescent biosensor for visualization of acetyl-CoA in live cells. [PDF]

Cell Chem Biol
Smith JJ, Valentino TR, Ablicki AH, Banerjee R, Colligan AR, Eckert DM, Desjardins GA, Diehl KL.   +7 more
europepmc   +1 more source

High‐Altitude Adaptation of Frogs (Case Study: Nanorana parkeri): From Physiological Phenotypes to AltitudeOmics

Integrative Zoology, EarlyView.
High altitudes are challenging for the animals that inhabit these environments. The Xizang plateau frog (Nanorana parkeri) survives in high‐altitude environments through a synergistic strategy of metabolic remodeling and protein expression adjustment to optimize energy efficiency and enhance cellular protection.
Xuejing Zhang, Yonggang Niu, Shengkang Men, Yanghuilin Zhang, Xiaolong Tang, Kenneth B. Storey, Qiang Chen   +6 more
wiley   +1 more source

Optimization of Malonyl Coenzyme A Biosensors in a Reconstituted Cell-Free System for Detecting Acetyl-CoA Carboxylase Activity. [PDF]

ACS Synth Biol
Ito S, Nishikawa S, Terasaka N, Fujishima K.   +3 more
europepmc   +1 more source

Monitoring spirodiclofen resistance in female Brevipalpus yothersi (Acari: Tenuipalpidae) from citrus orchards in Southeastern Brazil

Agricultural and Forest Entomology, EarlyView.
Spirodiclofen resistance levels in B. yothersi varied geographically across the Brazilian citrus belt, with higher resistance in the central region. Sublethal effects included reduced oviposition, increased non‐viable eggs and disrupted female reproduction.
Hector Alonso Escobar‐Garcia, Daniel Júnior de Andrade   +1 more
wiley   +1 more source