Results 31 to 40 of about 38,176 (241)

Programmed cell death in pathogenesis induced by herbicides inhibitors of acetyl-CoA-carboxylase

Біологічні студії, 2013
Importance of pathogenesis induced by herbicides whose phytotoxic action is caused by the interaction with photosynthesis is discussed. For this class of herbicides, the participation of programmed cell death and the role of reactive oxygen species (ROS)
A. M. Sychuk, M. P. Radchenko, Ye. Yu. Morderer   +2 more
doaj   +1 more source

Regulation of acetyl-coA carboxylase: properties of coA activation of acetyl-coA carboxylase. [PDF]

Proceedings of the National Academy of Sciences, 1980
Acetyl-CoA carboxylase [acetyl-CoA:carbon-dioxide ligase (ADP-forming), EC 6.4.1.2] is activated by physiological concentrations of CoA. The CoA concentration dependency of this activation is sigmoidal; below 60 microM there is little or no activation, but the activation observed between 60 and 120 microM indicates that small changes in the ...
L A, Yeh, K H, Kim
openaire   +2 more sources

Inhibition of rat liver acetyl CoA carboxylase by chloride

Journal of Lipid Research, 1980
The activity of acetyl CoA carboxylase in both crude and purified rat liver preparations was reduced in the presence of sodium or potassium chloride and increased in the presence of potassium acetate.
J B Allred, K L Roehrig
doaj   +1 more source

Fatty acid flux suppresses fatty acid synthesis in hamster intestine independently of SREBP-1 expression

Journal of Lipid Research, 2003
Hamsters were fed a control diet or diets containing palm, olive, safflower, or fish oil for 2 weeks. In villus cell populations from duodenum, jejunum, and ileum, rates of intestinal fatty acid and cholesterol synthesis were estimated, as were sterol ...
F. Jeffrey Field, Ella Born, Satya N. Mathur   +2 more
doaj   +1 more source

Rat epididymal adipose tissue acetyl-CoA carboxylase [PDF]

Canadian Journal of Biochemistry, 1970
The properties of a partially purified acetyl-CoA carboxylase (acetyl-CoA:CO2 ligase (ADP), EC 6.4.1.2) from rat epididymal fat pads have been studied. The properties of the rat adipose tissue enzyme are similar to those of the liver in regard to the pH optimum and affinity for substrates and inhibitors.
P R, Desjardins, K, Dakshinamurti
openaire   +2 more sources

Acetyl-CoA-Carboxylase 1-mediated de novo fatty acid synthesis sustains Lgr5+ intestinal stem cell function

Nature Communications, 2022
Here the authors report that inhibition of de novo fatty acid synthesis by deleting the enzyme Acetyl-CoA-Carboxylase 1 in the intestinal epithelium results in the loss of crypt structures and a specific decline in Lgr5+ intestinal epithelial stem cells.
Shuting Li, Chia-Wen Lu, Elia C. Diem, Wang Li, Melanie Guderian, Marc Lindenberg, Friederike Kruse, Manuela Buettner, Stefan Floess, Markus R. Winny, Robert Geffers, Hans-Hermann Richnow, Wolf-Rainer Abraham, Guntram A. Grassl, Matthias Lochner   +14 more
doaj   +1 more source

Metabolic Engineering of Pichia pastoris for the Production of Triacetic Acid Lactone

Journal of Fungi, 2023
Triacetic acid lactone (TAL) is a promising renewable platform polyketide with broad biotechnological applications. In this study, we constructed an engineered Pichia pastoris strain for the production of TAL.
Linjuan Feng, Junhao Xu, Cuifang Ye, Jucan Gao, Lei Huang, Zhinan Xu, Jiazhang Lian   +6 more
doaj   +1 more source

Cloning of human acetyl‐CoA carboxylase cDNA [PDF]

European Journal of Biochemistry, 1994
Acetyl‐CoA carboxylase is the rate‐limiting enzyme in the biogenesis of long‐chain fatty acids. In order to understand the mechanisms that regulate human acetyl‐CoA carboxylase at the gene level, and the relationship between its structure and function, cDNA clones for human acetyl‐CoA carboxylase have been isolated and sequenced.
J, Ha, S, Daniel, I S, Kong, C K, Park, H J, Tae, K H, Kim   +5 more
openaire   +2 more sources

In silico identification of potential inhibitors of acyl carrier protein reductase and acetyl CoA carboxylase of Plasmodium falciparum in antimalarial therapy

Frontiers in Drug Discovery, 2023
Malaria caused by Plasmodium falciparum, remains one of the most fatal parasitic diseases that has affected nearly a third of the world’s population. The major impediment to the treatment of malaria is the emergence of resistance of the P.
Elliasu Y. Salifu, James Abugri, James Abugri, Issahaku A. Rashid, Festus Osei, Joseph Atia Ayariga   +5 more
doaj   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source