Results 41 to 50 of about 56,101 (298)
Proceedings of the National Academy of Sciences of the United States of America, 2016 Significance Using structure-based drug design, we have identified a series of potent allosteric protein–protein interaction acetyl-CoA carboxylase inhibitors, exemplified by ND-630, that interact within the acetyl-CoA carboxylase subunit phosphopeptide ...
G. Harriman +10 more
semanticscholar +1 more source
The polymerization of acetyl-CoA carboxylase.
Journal of Biological Chemistry, 1983 Citrate, an allosteric activator of acetyl-CoA carboxylase, induces polymerization of an inactive protomeric form of the enzyme into an active filamentous form composed of 10-20 protomers. The light-scattering properties of the carboxylase were used to study the kinetics of its polymerization and depolymerization.
M D Lane, N B Beaty
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Interaction of acetyl‐CoA fragments with rat liver acetyl‐CoA carboxylase [PDF]
European Journal of Biochemistry, 1990 The interaction of acetyl‐CoA fragments with rat liver acetyl‐CoA carboxylase has been studied. Dephosphorylated acetyl‐CoA did not actually differ from acetyl‐CoA in its substrate properties. Non‐nucleotide analogues of the substrate, S‐acetylpantatheine and it's 4′‐phosphate, also possess substrate properties (Vmax= 1.5% and 15% of the maximal rate ...
Vera V. Velikodvorskaya +4 more
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Molecular Basis for Resistance to Fluazifop-P-Butyl in Itchgrass (Rottboellia cochinchinensis) from Costa Rica [PDF]
Planta Daninha, 2016 Rottboellia cochinchinensis is an annual grass weed species known as itchgrass, or "caminadora" in America´s Spanish speaking countries, and has become a major and troublesome weed in several crops.
R. CASTILLO-MATAMOROS +3 more
doaj +2 more sources
Genetics, 2022 Acetyl-CoA Carboxylase 1 catalyzes the conversion of acetyl-CoA to malonyl-CoA, the committed step of de novo fatty acid synthesis. As a master regulator of lipid synthesis, acetyl-CoA carboxylase 1 has been proposed to be a therapeutic target for ...
T. Pham +5 more
semanticscholar +1 more source
Programmed cell death in pathogenesis induced by herbicides inhibitors of acetyl-CoA-carboxylase
Біологічні студії, 2013 Importance of pathogenesis induced by herbicides whose phytotoxic action is caused by the interaction with photosynthesis is discussed. For this class of herbicides, the participation of programmed cell death and the role of reactive oxygen species (ROS)
A. M. Sychuk +2 more
doaj +1 more source
Environmental Toxicology, Volume 38, Issue 1, Page 225-242, January 2023., 2023 Abstract Per‐ and polyfluoroalkyl substances (PFAS), which include perfluorooctanoic acid (PFOA), heptafluorobutyric acid (HFBA), and perfluorotetradecanoic acid (PFTA), are commonly occurring organic pollutants. Exposure to PFAS affects the immune system, thyroid and kidney function, lipid metabolism, and insulin signaling and is also involved in the ...
Qi Qi +6 more
wiley +1 more source
Rubisco function, evolution, and engineering [PDF]
arXiv, 2022 Carbon fixation is the process by which CO2 is converted from a gas into biomass. The Calvin Benson Bassham (CBB) cycle is the dominant carbon fixation pathway on earth, driving >99.5% of the ~120 billion tons of carbon that are "fixed" as sugar, by plants, algae and cyanobacteria.
arxiv
Cysteine restriction‐specific effects of sulfur amino acid restriction on lipid metabolism
Aging Cell, Volume 21, Issue 12, December 2022., 2022 The proposed mechanism of CR‐specific effects of SAAR on adipose metabolism. (1) Due to the lack of Cys in SAAR diets, it imposes both MR and CR. CR specifically results in decreased biosynthesis of the tripeptide glutathione. (2) Lower hepatic glutathione increases the abundance of the transcription factor Nrf2, which translocates to the nucleus and ...
Sailendra N. Nichenametla +17 more
wiley +1 more source
Studies on the Intracellular Localization of Acetyl-CoA Carboxylase [PDF]
Biochemical and Biophysical Research Communications, 1997 The present work was performed to identify the subcellular localization of hepatic acetyl-CoA carboxylase (ACC). Cellular organelles involved in fatty acid oxidation that contain a malonyl-CoA sensitive carnitine palmitoyltransferase (CPT) activity or that are linked to the control of this activity were analysed for the presence of ACC.
M.J.H. Geelen +4 more
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