Results 41 to 50 of about 82,191 (356)
Complex formation and regulation of Escherichia coli acetyl-CoA carboxylase [PDF]
, 2013 Acetyl-CoA carboxylase is a biotin-dependent, multifunctional enzyme that catalyzes the first committed step in fatty acid synthesis. The Escherichia coli enzyme is composed of a homodimeric biotin carboxylase, biotinylated biotin carboxyl carrier ...
Broussard, Tyler Craig
core +2 more sources
Acetyl CoA Carboxylase 2 Is Dispensable for CD8+ T Cell Responses. [PDF]
PLoS ONE, 2015 Differentiation of T cells is closely associated with dynamic changes in nutrient and energy metabolism. However, the extent to which specific metabolic pathways and molecular components are determinative of CD8+ T cell fate remains unclear.
Jang Eun Lee +5 more
doaj +1 more source
Proceedings of the National Academy of Sciences of the United States of America, 2016 Significance Using structure-based drug design, we have identified a series of potent allosteric protein–protein interaction acetyl-CoA carboxylase inhibitors, exemplified by ND-630, that interact within the acetyl-CoA carboxylase subunit phosphopeptide ...
G. Harriman +10 more
semanticscholar +1 more source
The synthesis of new biotin derivatives and their bioactivity [PDF]
, 2002 Biotin is an essential growth factor found in all living cells. It functions as a cofactor for a group of coenzymes that catalyze transcarboxylation, decarboxylation, and carboxylation reactions.
Johnson, Latisha Chanette
core +2 more sources
The polymerization of acetyl-CoA carboxylase.
Journal of Biological Chemistry, 1983 Citrate, an allosteric activator of acetyl-CoA carboxylase, induces polymerization of an inactive protomeric form of the enzyme into an active filamentous form composed of 10-20 protomers. The light-scattering properties of the carboxylase were used to study the kinetics of its polymerization and depolymerization.
M D Lane, N B Beaty
openaire +3 more sources
Interaction of acetyl‐CoA fragments with rat liver acetyl‐CoA carboxylase [PDF]
European Journal of Biochemistry, 1990 The interaction of acetyl‐CoA fragments with rat liver acetyl‐CoA carboxylase has been studied. Dephosphorylated acetyl‐CoA did not actually differ from acetyl‐CoA in its substrate properties. Non‐nucleotide analogues of the substrate, S‐acetylpantatheine and it's 4′‐phosphate, also possess substrate properties (Vmax= 1.5% and 15% of the maximal rate ...
Vera V. Velikodvorskaya +4 more
openaire +3 more sources
Activation of AMP-activated protein kinase by metformin induces protein acetylation in prostate and ovarian cancer cells [PDF]
, 2016 AMP-activated protein kinase (AMPK) is an energy sensor and master regulator of metabolism. AMPK functions as a fuel gauge monitoring systemic and cellular energy status.
Galdieri, Luciano +3 more
core +2 more sources
Molecular Basis for Resistance to Fluazifop-P-Butyl in Itchgrass (Rottboellia cochinchinensis) from Costa Rica [PDF]
Planta Daninha, 2016 Rottboellia cochinchinensis is an annual grass weed species known as itchgrass, or "caminadora" in America´s Spanish speaking countries, and has become a major and troublesome weed in several crops.
R. CASTILLO-MATAMOROS +3 more
doaj +2 more sources
Inhibitors of Pyruvate Carboxylase [PDF]
, 2010 This review aims to discuss the varied types of inhibitors of biotin-dependent carboxylases, with an emphasis on the inhibitors of pyruvate carboxylase.
Attwood, Paul V. +2 more
core +2 more sources
Programmed cell death in pathogenesis induced by herbicides inhibitors of acetyl-CoA-carboxylase
Біологічні студії, 2013 Importance of pathogenesis induced by herbicides whose phytotoxic action is caused by the interaction with photosynthesis is discussed. For this class of herbicides, the participation of programmed cell death and the role of reactive oxygen species (ROS)
A. M. Sychuk +2 more
doaj +1 more source