Results 61 to 70 of about 28,974 (220)

Investigations into β-ketoacyl-ACP Synthase III and enoyl-ACP reductase of plant fatty acid synthase [PDF]

, 1999
An antisense transgenic approach was taken in order to assess the importance of P-ketoacyl-ACP- Synthase III (KAS III) in regulation and initiation of de novo fatty acid synthesis in planta.
Clarke, Hayley Diana
core  

Reciprocal regulation of protein synthesis and carbon metabolism for thylakoid membrane biogenesis [PDF]

, 2013
Metabolic control of gene expression coordinates the levels of specific gene products to meet cellular demand for their activities. This control can be exerted by metabolites acting as regulatory signals and/or a class of metabolic enzymes with dual ...
Bohne, Alexandra-Viola, Marco Schottkowski, Michael Lidschreiber, Zerges, William, Markus Piotrowski (169373), Markus Piotrowski, Michael Lidschreiber (138963), Christian Schwarz, Alexandra-Viola Bohne (281295), Marco Schottkowski (281297), William Zerges, Nickelsen, Jörg, Jörg Nickelsen (13576), Piotrowski, Markus, Alexandra-Viola Bohne, Christian Schwarz (281296), Lidschreiber, Michael, Jörg Nickelsen, Schottkowski, Marco, Schwarz, Christian, William Zerges (95563)   +20 more
core   +1 more source

Acetate Induces Growth Arrest in Colon Cancer Cells Through Modulation of Mitochondrial Function

Frontiers in Nutrition, 2021
Acetate is one of the main short chain fatty acids produced in the colon when fermentable carbohydrates are digested. It has been shown to affect normal metabolism, modulating mitochondrial function, and fatty acid oxidation. Currently, there is no clear
Meliz Sahuri-Arisoylu, Meliz Sahuri-Arisoylu, Rhys R. Mould, Noriko Shinjyo, S. W. Annie Bligh, S. W. Annie Bligh, Alistair V. W. Nunn, Geoffrey W. Guy, Elizabeth Louise Thomas, Jimmy D. Bell   +9 more
doaj   +1 more source

The overexpression and characterisation of Enoyl ACP Reductase from Brassica. napus: a component enzyme of fatty acid synthetase in plants [PDF]

, 1995
The main objective of this research is to advance our understanding at the structural and expressional level of plant enoyl ACP reductase (ER), the enzyme which catalyses the last reductive step in the de-novo biosynthesis of fatty acids.
Simon, Josiah William
core  

Ethanol represses the expression of methanol-inducible genes via acetyl-CoA synthesis in the yeast Komagataella phaffii [PDF]

, 2018
In methylotrophic yeasts, the expression of methanol-inducible genes is repressed by ethanol even in the presence of methanol, a phenomenon called ethanol repression.
Ohsawa, Shin, Sakai, Yasuyoshi, Nishida, Susumu, Yurimoto, Hiroya, Oku, Masahide   +4 more
core   +1 more source

Mitochondrial acetyl-CoA reprogramming by the SIRT3–ACSS2–OPA1 axis confers resistance to ferroptosis in Parkinson's disease

Redox Biology
Mitochondrial dysfunction and ferroptosis have emerged as pivotal contributors to dopaminergic (DA) neuron degeneration in Parkinson's disease (PD).
Xv-shen Ding, Bao Wang, Zheng Han, Chen-xi Feng, Yang-ni Li, Yu-fei Wang, Jian-cai Guru, Jie Cao, Rui-li Zhang, Xue-lian Wang, Qian Yang, Yan Qu, Li Gao   +12 more
doaj   +1 more source

Post‐Translational Modifications of Key Proteins in Hematologic Malignancies: Carcinogenic Mechanisms, Biomarker Potential, and New Therapeutic Strategies

iLABMED, EarlyView.
This article reviews the pivotal role of post‐translational modifications of proteins in the development and progression of hematologic malignancies, and explores their clinical translation potential as novel biomarkers and therapeutic targets. ABSTRACT Post‐translational modifications (PTMs) of proteins have emerged as critical regulators in the ...
Yuxuan Han, Chaowei Zhang, Weiyi Yao, Qing Hong, Xinyu Tang, Yanan Zhu, Na Chen   +6 more
wiley   +1 more source

Isolation of an acetyl-CoA synthetase gene (ZbACS2) from Zygosaccharomyces bailii [PDF]

, 2004
A gene homologous to Saccharomyces cerevisiae ACS genes, coding for acetyl-CoA synthetase, has been cloned from the yeast Zygosaccharomyces bailii ISA 1307, by using reverse genetic approaches. A probe obtained by PCR amplification from Z. bailii DNA,
Manuela Côrte‐Real, Côrte-Real, Manuela, Cardoso, M. Helena, Zeeman, Anne-Marie, Maria João Sousa, Sousa, Maria João, Steensma, H. Yde, Anne‐Marie Zeeman, Fernando Rodrigues, Rodrigues, Fernando José dos Santos, Cecília Leão, Helena Cardoso, H. Yde Steensma, Leão, Cecília   +13 more
core   +1 more source

Adss1–HDAC3 Interaction: A Novel Mechanism for Epigenetic Regulation of Metabolism in Adipose Tissue

iNew Medicine, EarlyView.
ABSTRACT Obesity and its related metabolic disorders have emerged as global public health challenges with underlying mechanisms involving an imbalance between energy storage and expenditure in the adipose tissue. In recent years, with the deepening research on adipose tissue metabolism, the cross talk between metabolic enzymes and epigenetic regulation
Jiarui Zhao, Jingjing Sun, Yan Lu, Ying Yang   +3 more
wiley   +1 more source

Understanding the Role of Nuclear Acetyl-CoA Synthetase 2 in Maintaining Histone Acetylation

, 2022
Histone acetylation is governed by nuclear acetyl-CoA pools generated in part from local acetate by metabolic enzyme acetyl-CoA synthetase 2 (ACSS2). We hypothesize that during gene activation, a local transfer of intact acetate occurs via sequential ...
Mendoza, Mariel
core   +1 more source