Results 81 to 90 of about 28,974 (220)

Apple scar skin viroid causes dapple and scar skin apple diseases by disrupting phenylpropanoid‐mediated metabolic pathways

New Plant Protection, EarlyView.
Dapple apple and scar skin apple diseases are closely associated with suppression of anthocyanin biosynthesis and enhancement of suberin biosynthesis. Apple scar skin viroid (ASSVd) infection represses anthocyanin biosynthesis in apple callus. Abstract Apple scar skin viroid (ASSVd) causes dapple and scar skin apple diseases, posing serious threats to ...
Lingzhu He, Huiyuan Xu, Tao Zhou, Naoi Takashi, Sano Teruo, Guojun Hu, Jipeng Xie, Xiuling Yang, Shifang Li, Zhixiang Zhang   +9 more
wiley   +1 more source

Proteome Analysis of Corynebacterium diphtheriae–Macrophage Interaction

PROTEOMICS, EarlyView.
ABSTRACT Contact of Corynebacterium diphtheriae with macrophages induces adaptations on both bacterial and cellular sides. The study presented here was aiming to shed light on the simultaneous intracellular adaptation of the bacteria and changes in the proteome of the phagocytes in response to the internalization of C. diphtheriae.
Luca Musella, Jens Möller, Christopher Lischer, Julio Vera‐Gonzalez, Jörg Hofmann, Lisa Ott, Andreas Burkovski   +6 more
wiley   +1 more source

Role of Acetyl-CoA Synthetase 2 and Acetyl-CoA Precursors, Acetate and Ethanol, on Hepatocyte Gene Expression

, 2016
Abnormally high blood and tissue lipid levels observed in metabolic disorders and cardiovascular diseases are associated with extensive gene expression changes.
Erickson,, Anjeza, Bruner, Noel, Xia, Mengna, Moreau, Regis, Erickson, Anjeza, He, Bo   +5 more
core  

Proteomic Profiling of Primary Hippocampal Neurons Reveals Noncanonical GFAP Expression and Metabolic Adaptations in Glia‐Free Culture

PROTEOMICS, EarlyView.
ABSTRACT Despite their widespread use as a research model, a comprehensive, quantitative proteomic profile of the cultured hippocampal neurons has remained unexplored. Here, we provide the first global proteomic characterization of primary murine hippocampal neurons cultured for 14 days under near‐physiological glucose conditions (2.5 mM).
Dominika Drulis‐Fajdasz, Kinga Gostomska‐Pampuch, Natalia Pudełko‐Malik, Mariusz Fleszar, Agnieszka Gizak, Jacek R. Wiśniewski, Dariusz Rakus   +6 more
wiley   +1 more source

ACSS2 protects against alcohol-induced hepatocyte ferroptosis through regulation of hepcidin expression

Nature Communications
Acetate is the end product of alcohol metabolism. Acyl-CoA synthetase short-chain family member 2 (ACSS2) converts acetate to acetyl-CoA, involving metabolic pathways and epigenetic regulation.
Mengyao Wang, Xiao Wen, Zian Feng, Mayank Choubey, Shasha Chen, Ruru Pan, Ke Gong, Munichandra Babu Tirumalasetty, Fei Gao, Chenzhong Liao, Zequn Yin, Shuang Zhang, Yong He, Houzao Chen, Yang Cao, Qing Robert Miao, Wenquan Hu, Yajun Duan   +17 more
doaj   +1 more source

Universal and Lineage‐Specific Patterns in the Distribution of ECOD Domain Homology Groups Across Superkingdoms

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Proteins are built from modular domains that serve as fundamental units of structure and evolution. While individual domains have been extensively cataloged, their collective distribution across the lineages of life has remained poorly resolved.
Rui Guo, Jimin Pei, Jing Zhang, Qian Cong, Nick V. Grishin, R. Dustin Schaeffer   +5 more
wiley   +1 more source

Essential oils as bioherbicides: effects of orange and citronella oils on weed germination and early growth

Pest Management Science, EarlyView.
Essential oils from orange and citronella showed dose‐dependent inhibition of weed germination and early growth, highlighting their potential as bioherbicides and sustainable tools for integrated weed management. Abstract BACKGROUND Increasing selection of herbicide‐resistant weed biotypes has intensified the search for alternatives to the intensive ...
Geovana Rocha Marzochi, Leonardo de Oliveira Semensato, Francielli Santos de Oliveira, Virginia Claudia Paulino Silva, Eliane Gomes Fabri, Evandro Henrique Schinor, Andréia Cristina Silva Hirata, Moacir Rossi Forim, Angélica Correa Kauffmann, Patricia Andrea Monquero   +9 more
wiley   +1 more source

Studies towards the isolation of a functional plant dehydratase of fatty acid biosynthesis [PDF]

, 2000
Not ...
Doig, Simon
core  

The influence of ACSS2 knockdown on the proliferation, apoptosis and migration of NSCLC cell line A549

Zhongguo aizheng zazhi, 2016
Background and purpose: Metabolism change is one of the main characteristics of the tumor development. Many studies have confirmed that cytosolic acetyl-CoA synthetase 2 (ACSS2) plays a critical role in hydrocarbon metabolism of cancer cells.
卢晓霞, 常　淑, 毕明宏
doaj  

Isothiocyanates as Ferroptosis Inducers to Promote Cancer Cell Death

Phytotherapy Research, EarlyView.
ABSTRACT Cancer remains a leading cause of global mortality, with the therapeutic efficacy of anticancer drugs often hampered by late diagnosis and the development of chemotherapy resistance. Ferroptosis is an iron‐dependent form of regulated non‐apoptotic cell death driven by lipid peroxidation.
Valentina Citi, Renda Chahna, Francesca Maffei, Alma Martelli, Vincenzo Calderone, Carmela Fimognari, Eleonora Turrini   +6 more
wiley   +1 more source