Natural and Synthetic Metabolic Architectures
ChemBioChem, Volume 27, Issue 7, 14 April 2026.Metabolism yields function through architecture, not through isolated parts. This Perspective article discusses how design can move from components to connectivity and then to architectural regimes that account for space, time, and routing. The framework links understanding to engineering and helps explain why microbial engineering meets challenges ...
Pablo I. Nikel
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Biological Degradation of Phthalates: From Bioremediation to Plastic Waste Valorization
ChemSusChem, Volume 19, Issue 7, 14 April 2026.Phthalic acid isomers play a key role in the plastics industry, but pose significant environmental and health concerns. This review explores the microbial biodegradation of phthalates and their esters, focusing on bacterial enzymes, catabolic pathways, and cellular uptake mechanisms of phthalates.
Marco A. Pereyra‐Camacho, Isabel Pardo
wiley +1 more source
Staphylococcus aureus modulates the activity of acetyl-Coenzyme A synthetase (Acs) by sirtuin-dependent reversible lysine acetylation. [PDF]
Mol Microbiol, 2019 Burckhardt RM +2 more
europepmc +1 more source
Targeting host metabolism by inhibition of acetyl-Coenzyme A carboxylase reduces flavivirus infection in mouse models. [PDF]
Emerg Microbes Infect, 2019 Jiménez de Oya N +15 more
europepmc +1 more source
N-Acetyltransferase 1 Knockout Elevates Acetyl Coenzyme A Levels and Reduces Anchorage-Independent Growth in Human Breast Cancer Cell Lines. [PDF]
J Oncol, 2019 Stepp MW +4 more
europepmc +1 more source
Acetyl-coenzyme A synthetase gene ChAcs1 is essential for lipid metabolism, carbon utilization and virulence of the hemibiotrophic fungus Colletotrichum higginsianum. [PDF]
Mol Plant Pathol, 2019 Gu Q +6 more
europepmc +1 more source
A Biochemical Nickel(I) State Supports Nucleophilic Alkyl Addition: A Roadmap for Methyl Reactivity in Acetyl Coenzyme A Synthase. [PDF]
Inorg Chem, 2019 Manesis AC +5 more
europepmc +1 more source
Fitness costs associated with acetyl-coenzyme A carboxylase mutations endowing herbicide resistance in American sloughgrass (Beckmannia syzigachne Steud.). [PDF]
Ecol Evol, 2019 Du L +6 more
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THE OXIDATION OF ACETALDEHYDE TO ACETYL COENZYME A
Journal of Biological Chemistry, 1953 R M, BURTON, E R, STADTMAN
openaire +2 more sources
Re-engineering of acetyl coenzyme A metabolism prevents senescence in budding yeast
Hadj-Moussa H +4 more
europepmc +1 more source