Results 31 to 40 of about 25,053 (234)

Acetyl-L-Carnitine in Parkinson’s Disease [PDF]

, 2012
Parkinson’s disease (PD) is the most common neurodegenerative movement disorder that is estimated to affect approximately 1% of the population older than 65 years of age (deRijk et al., 2006; Saunders, 2000). PD was first described in 1818 by the British physician J. Parkinson.
SINICROPI, Maria Stefania, N. Rovito, A. Carocci, G. Genchi   +3 more
openaire   +3 more sources

Oral Acetyl-L-Carnitine treatment in hepatic encephalopathy: view of evidence-based medicine

Annals of Hepatology, 2013
Objective. To systematically review the effect of Acetyl-L-Carnitine in patients with hepatic encephalopathy.Material and methods. Design: systematic review and meta-analysis.
Qian Jiang, Gang Jiang, Ke-qing Shi, Hong Cai, Yi-xin Wang, Ming-hua Zheng   +5 more
doaj   +1 more source

Perfluorosulfonic Acid Membranes with Short and Long Side Chains and Their Use in Sensors for the Determination of Markers of Viral Diseases in Saliva

Membranes, 2023
The development of accessible express methods to determine markers of viral diseases in saliva is currently an actual problem. Novel cross-sensitive sensors based on Donnan potential with bio-comparable perfluorosulfonic acid membranes for the ...
Anna V. Parshina, Ekaterina Yu. Safronova, Svetlana A. Novikova, Nastasia Stretton, Anastasia S. Yelnikova, Timur R. Zhuchkov, Olga V. Bobreshova, Andrey B. Yaroslavtsev   +7 more
doaj   +1 more source

Increased levels of RNA oxidation enhance the reversion frequency in aging pro-apoptotic yeast mutants [PDF]

, 2016
Despite recent advances in understanding the complexity of RNA processes, regulation of the metabolism of oxidized cellular RNAs and the mechanisms through which oxidized ribonucleotides affect mRNA translation, and consequently cell viability, are not ...
A Nunomura, AJ Kemp, C Chen, C Falcone, C Mazzoni, C Mazzoni, C Mazzoni, C Mazzoni, C Mazzoni, C Mazzoni, CK Mathews, CL Simms, Claudio Falcone, Cristina Mazzoni, D Carmona-Gutierrez, F Madeo, F Madia, F Stutz, F Taddei, H Kamiya, Joanna Kufel, Mariarita Stirpe, Matteo Ferrari, ME Schmitt, S Tharun, Seweryn Mroczek, T Hofer, T Hofer, TW Traut, V Palermo, V Palermo, V Palermo, V Palermo, Vanessa Palermo, X Shan, Y Chang, Z Li   +36 more
core   +2 more sources

Sirtuin3 Dysfunction Is the Key Determinant of Skeletal Muscle Insulin Resistance by Angiotensin II. [PDF]

PLoS ONE, 2015
Angiotensin II promotes insulin resistance. The mechanism underlying this abnormality, however, is still poorly defined. In a different setting, skeletal muscle metabolism and insulin signaling are regulated by Sirtuin3.Here, we investigate whether ...
Daniela Macconi, Luca Perico, Lorena Longaretti, Marina Morigi, Paola Cassis, Simona Buelli, Norberto Perico, Giuseppe Remuzzi, Ariela Benigni   +8 more
doaj   +1 more source

An acetyl-L-carnitine switch on mitochondrial dysfunction and rescue in the metabolomics study on aluminum oxide nanoparticles [PDF]

, 2015
BACKGROUND: Due to the wide application of engineered aluminum oxide nanoparticles and increased aluminum containing particulate matter suspending in air, exposure of human to nano-scale aluminum oxide nanoparticles (Al(2)O(3) NPs) is becoming inevitable.
Chengcheng Zhang, Hongbao Yang, Qingtao Meng, Rui Chen, Shenshen Wu, Shizhi Wang, Xiaobo Li, Xin Zhang, Yankai Xia   +8 more
core   +1 more source

The Protective Effects of Acetyl L-Carnitine on Testis Gonadotoxicity Induced by Cisplatin in Rats

Balkan Medical Journal, 2013
Background: Cisplatin, an effective antineoplastic agent, damages normal cells in a manner related to chemotherapy. Acetyl L-carnitine protects cells against mitochondrial and nuclear damage induced by chemotherapy. Aims: The aim of this study was to
Neslihan Coşkun, M. Tahir Hatipoğlu, Candan Özoğul, Seda Nur Akyol, Gülistan Sanem Arık, Deniz Erdoğan, Cem Korkmaz, Serap Cilaker Mıcılı   +7 more
doaj   +1 more source

Methamphetamine promotes a-tubulin deacetylation in endothelial cells: The protective role of acetyl-L-carnitine [PDF]

, 2015
Methamphetamine (METH) is a powerful psychostimulant drug used worldwide for its reinforcing properties. In addition to the classic long-lasting monoaminergic-disrupting effects extensively described in the literature, METH has been consistently reported
Fernandes, Sílvia, Salta, Sofia, Summavielle, Teresa   +2 more
core   +1 more source

Body mass index and age correlate with antioxidant supplementation effects on sperm quality: Post hoc analyses from a double-blind placebo-controlled trial [PDF]

, 2020
Spermatozoa are vulnerable to lack of energy and oxidative stress as a result of elevated levels of reactive oxygen species. Therefore, it is essential that appropriate nutrients are available during maturation.
Agarwal, Ashok, Busetto, Gian Maria, Chung, Benjamin I, De Berardinis, Ettore, Del Giudice, Francesco, Ferro, Matteo, Maggi, Martina, Porreca, Angelo, Sciarra, Alessandro, Virmani, Ashraf   +9 more
core   +1 more source

Acetyl-l-carnitine normalizes the impaired long-term potentiation and spine density in a rat model of global ischemia [PDF]

, 2014
Aim: The aim of this study was to enhance the knowledge regarding actors and intentions in the development process of a mobile phone platform for self-management of hypertension.
Kocsis, Kitti, Knapp, Levente, Gellért, Levente, Oláh, Gáspár, Kis, Zsolt, Takakuwa, H., Iwamori, N., Ono, E., Toldi, József, Farkas, Tamás   +9 more
core   +1 more source