Results 111 to 120 of about 2,632,092 (318)
O -Acetylated sugars in the gas phase: stability, migration, positional isomers and conformation [PDF]
O-acetylations are functional modifications which can be found on different hydroxyl groups of glycans and which contribute to the fine tuning of their biological activity. Localizing the acetyl modifications is notoriously challenging in glycoanalysis, in particular because of their mobility: loss or migration of the acetyl group may occur through the
arxiv +1 more source
Beating the acetyl coenzyme A-pathway to the origin of life
Attempts to draft plausible scenarios for the origin of life have in the past mainly built upon palaeogeochemical boundary conditions while, as detailed in a companion article in this issue, frequently neglecting to comply with fundamental thermodynamic ...
W. Nitschke, M. Russell
semanticscholar +1 more source
BackgroundButanol isomers are regarded as more suitable fuel substitutes than bioethanol. n-Butanol is naturally produced by some Clostridia species, but due to inherent problems with clostridial fermentations, industrially more relevant organisms have ...
Virginia Schadeweg, E. Boles
semanticscholar +1 more source
Role of acetylation in nonalcoholic fatty liver disease: a focus on SIRT1 and SIRT3
Nonalcoholic fatty liver disease (NAFLD) has become the most prevalent liver chronic disease worldwide. The pathogenesis of NAFLD is complex and involves many metabolic enzymes and multiple pathways.
Fatiha Nassir
doaj +1 more source
Background— Carnitine acetyltransferase catalyzes the reversible conversion of acetyl-coenzyme A (CoA) into acetylcarnitine. The aim of this study was to use the metabolic tracer hyperpolarized [2-13C]pyruvate with magnetic resonance spectroscopy to ...
M. Schroeder+7 more
semanticscholar +1 more source
Structural Basis for the Catalytic Mechanism of ATP‐Dependent Diazotase CmaA6
Although several diazotases have been recently reported, the details of the reaction mechanism are not yet understood. In this study, we investigated the mechanism of CmaA6, an ATP‐dependent diazotase that catalyzes the diazotization of 3‐aminocoumaric acid using nitrous acid.
Seiji Kawai+5 more
wiley +1 more source
Simulation of Drosophila Circadian Oscillations, Mutations, and Light Responses by a Model with VRI, PDP-1, and CLK [PDF]
A model of Drosophila circadian rhythm generation was developed to represent feedback loops based on transcriptional regulation of per, Clk (dclock), Pdp-1, and vri (vrille). The model postulates that histone acetylation kinetics make transcriptional activation a nonlinear function of [CLK]. Such a nonlinearity is essential to simulate robust circadian
arxiv +1 more source
Thirty multiparous lactating dairy cows were used in a randomized block design experiment to evaluate factors related to the degree of hypophagia from intraruminal infusion of propionate.
S. Stocks, M. S. Allen
semanticscholar +1 more source
Electron spin and the origin of Bio-homochirality I. Extant enzymatic reaction model [PDF]
In this paper, I tentatively put forward a new hypothesis that the emergence of a single chiral form of biomolecules in living organisms is specifically determined by the electron spin state during their enzyme-catalyzed synthesis processes. Specifically speaking, the electrons released from the coenzyme NAD(P)H of amino acid synthase are heterogeneous
arxiv
Ignicoccus hospitalis, a hyperthermophilic, chemolithoautotrophic crenarchaeon was found to possess a new CO2 fixation pathway, the dicarboxylate/4-hydroxybutyrate cycle.
F. Mayer+6 more
semanticscholar +1 more source