Results 211 to 220 of about 49,331 (295)
Journal of Inherited Metabolic Disease, Volume 49, Issue 1, January 2026.Cardiac bioenergetic and metabolic perturbations in late‐stage Leigh syndrome. Whole‐body NDUFS4 loss severely impairs cardiac complex I activity and respiration, shifting reliance to complex II and reducing glycolytic, TCA, and amino acid‐derived energy‐generating substrates in the heart.
Karin Terburgh +2 more
wiley +1 more source
Acetyl-coenzyme A synthetase gene ChAcs1 is essential for lipid metabolism, carbon utilization and virulence of the hemibiotrophic fungus Colletotrichum higginsianum. [PDF]
Mol Plant Pathol, 2019 Gu Q +6 more
europepmc +1 more source
Holocarboxylase Synthetase Deficiency: A Second Case Report With Neonatal Cholestatic Liver Disease
JIMD Reports, Volume 67, Issue 1, January 2026.ABSTRACT Holocarboxylase synthetase deficiency is an autosomal recessive inborn error of metabolism characterised by life‐threatening metabolic acidosis, ketoacidosis and hyperammonaemia through reduced biotin‐dependent carboxylase activity. We report the presentation of a Polynesian neonate with severe metabolic acidosis secondary to holocarboxylase ...
Sophie Manoy +9 more
wiley +1 more source
Molecular Nutrition &Food Research, Volume 70, Issue 1, January 2026.Sulforaphane (SFN) is an isothiocyanate derived from broccoli and is related to various health‐promoting effects. By using metabolic profiling on the hepatoblastoma cell line HepG2 several effects on pathways such as TCA cycle, urea cycle and redox metabolism through SFN were identified.
Nadine Bieß +3 more
wiley +1 more source
PROTEOMICS, Volume 26, Issue 1, Page 44-56, January 2026.ABSTRACT The EmDia trial, designed to study the effects of the sodium glucose cotransporter‐2 (SGLT2) inhibitor empagliflozin on cardiovascular comorbidities in type 2 diabetes mellitus (T2DM) patients, has been investigated for short‐term metabolic alterations by a limited set of clinical assays. To expand on this data, we report on the development of
Fabian Schmitt +7 more
wiley +1 more source
Wheat acetyl-coenzyme A carboxylase: cDNA and protein structure.
, 1994 Piotr Górnicki +5 more
openalex +2 more sources
Structural basis of product recognition by Mycobacterium tuberculosis fatty acid synthase
Protein Science, Volume 35, Issue 1, January 2026.Abstract Microbial iterative fatty acid synthases (FAS) are versatile multienzymes under scrutiny for their potential as anti‐infectious targets and their biotechnological applications. They produce saturated fatty acids with defined chain length and release them as coenzyme A‐conjugates.
Elnaz Khalili Samani +4 more
wiley +1 more source
Fitness costs associated with acetyl-coenzyme A carboxylase mutations endowing herbicide resistance in American sloughgrass (Beckmannia syzigachne Steud.). [PDF]
Ecol Evol, 2019 Du L +6 more
europepmc +1 more source