Results 221 to 230 of about 2,632,092 (318)

Association analysis between Acetyl-Coenzyme A Acyltransferase-1 gene polymorphism and growth traits in Xiangsu pigs. [PDF]

Front Genet
Xiao M, Ruan Y, Huang J, Dai L, Xu J, Xu H.   +5 more
europepmc   +1 more source

Human γδ T Cell Function Is Impaired Upon Mevalonate Pathway Inhibition

Immunology, EarlyView.
Mevalonate pathway is important for the effector function of gammadelta T cells. Inhibition of the pathway in vivo and in vitro impairs cytokine and cytotoxic molecule production by mainly affecting protein prenylation and disturbing intracellular signalling in Vdelta2 T cells. Created with Biorender.
Tsz Kin Suen, Burcu Al, Thomas Ulas, Nico Reusch, Harsh Bahrar, Siroon Bekkering, Jaydeep Bhat, Dieter Kabelitz, Joachim L. Schultze, Frank L. van de Veerdonk, Jeanine Roeters van Lennep, Niels P. Riksen, Leo A. B. Joosten, Mihai G. Netea, Katarzyna Placek   +14 more
wiley   +1 more source

Equilibrium Constants of the Malate Dehydrogenase, Citrate Synthase, Citrate Lyase, and Acetyl Coenzyme A Hydrolysis Reactions under Physiological Conditions

, 1973
Robert W. Guynn, Harris J. Gelberg, Richard L. Veech   +2 more
openalex   +1 more source

Subcellular localization and ionic properties of acetyl-coenzyme A synthetase in the electric organ of Torpedo marmorata [PDF]

, 1979
Y. Morot‐Gaudry, M. F. Diebler
openalex   +1 more source

Medium- and long-chain triglyceride propofol reduces the activity of acetyl-coenzyme A carboxylase in hepatic lipid metabolism in HepG2 and Huh7 cells. [PDF]

Korean J Physiol Pharmacol, 2020
Wang LY, Wu J, Gao YF, Lin DM, Ma J.
europepmc   +1 more source

Regulation of Hepatic Acetyl Coenzyme A Carboxylase by Phosphorylation and Dephosphorylation

, 1973
Curtis A. Carlson, Ki-Han Kim
openalex   +1 more source

The atypical velocity response by pyruvate carboxylase to increasing concentrations of acetyl-coenzyme A [PDF]

, 1979
Simon B. Easterbrook‐Smith, Anne J. Campbell, D.B. Keech, John C. Wallace   +3 more
openalex   +1 more source

Metabolomics in cardiometabolic diseases: Key biomarkers and therapeutic implications for insulin resistance and diabetes

Journal of Internal Medicine, EarlyView.
Abstract Cardiometabolic diseases—including Type 2 diabetes and obesity—remain leading causes of global mortality. Recent advancements in metabolomics have facilitated the identification of metabolites that are integral to the development of insulin resistance, a characteristic feature of cardiometabolic disease. Key metabolites, such as branched‐chain
David Rizo‐Roca, John D. Henderson, Juleen R. Zierath   +2 more
wiley   +1 more source

Acetyl-CoA synthesis in the skin is a key determinant of systemic lipid homeostasis

Cell Reports
Summary: ATP-citrate lyase (ACLY) generates cytosolic acetyl-coenzyme A (acetyl-CoA) for lipid synthesis and is a promising therapeutic target in diseases with altered lipid metabolism.
Phuong T.T. Nguyen, Mia Shiue, Nina Kuprasertkul, Pedro Costa-Pinheiro, Luke T. Izzo, Laura V. Pinheiro, Hayley A. Affronti, Gabriel Gugiu, Shivani Ghaisas, Joyce Y. Liu, Jordan C. Harris, Charles W. Bradley, John T. Seykora, Xiaolu Yang, Taku Kambayashi, Clementina Mesaros, Brian C. Capell, Kathryn E. Wellen   +17 more
doaj  

Increase in acetyl coenzyme a carboxylase‐synthesizing polysomes in the livers of genetically obese mice [PDF]

, 1976
Tadashi Tanabe, Saburo Horikawa, Shigetada Nakanishi, Shosaku Numa   +3 more
openalex   +1 more source