Results 11 to 20 of about 374,029 (398)
Analysis of human acetylation stoichiometry defines mechanistic constraints on protein regulation
Nature Communications, 2019 Many human proteins are regulated by lysine acetylation, but the degree of acetylation at individual sites is poorly characterized. Here, the authors measure acetylation stoichiometry in the HeLa cell proteome, providing a resource to assess mechanistic ...
Bogi Karbech Hansen +7 more
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Protein lysine acetylation regulates oral microorganisms [PDF]
Frontiers in Cellular and Infection MicrobiologyPost-translational modifications (PTMs) are integral to the regulation of protein function, stability, and cellular processes. Lysine acetylation, a widespread PTM, has been extensively characterized for its role in eukaryotic cellular functions ...
Yuanchao Yang +11 more
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The world of protein acetylation
Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 2016 Acetylation is one of the major post-translational protein modifications in the cell, with manifold effects on the protein level as well as on the metabolome level. The acetyl group, donated by the metabolite acetyl-coenzyme A, can be co- or post-translationally attached to either the α-amino group of the N-terminus of proteins or to the ε-amino group ...
Adrian Drazic +4 more
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Agricultural and Biological Chemistry, 1968 In order to elucidate the significance of amino groups as active groups of lysozyme, egg white lysozyme was acetylated with acetic anhydride. The acetylated lysozyme was fractionated by CM-cellulose column chromatography. All acetylated lysozymes fractionated exhibited 120% relative activity toward glycol chitin at pH 5.6, while the optimum pH shifted ...
Masaru Funatsu +2 more
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Swelling of acetylated wood in organic liquids [PDF]
, 2005 To investigate the affinity of acetylated wood for organic liquids, Yezo spruce wood specimens were acetylated with acetic anhydride, and their swelling in various liquids were compared to those of untreated specimens. The acetylated wood was rapidly and
A. N. NAYER +10 more
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Cell Death and Differentiation, 2021 High circulating levels of lactate and high mobility group box-1 (HMGB1) are associated with the severity and mortality of sepsis. However, it is unclear whether lactate could promote HMGB1 release during sepsis.
Kun Yang +10 more
semanticscholar +1 more source
Acetylation in the regulation of autophagy
Autophagy, 2022 Post-translational modifications, such as phosphorylation, ubiquitination and acetylation, play crucial roles in the regulation of autophagy. Acetylation has emerged as an important regulatory mechanism for autophagy.
Yinfeng Xu, W. Wan
semanticscholar +1 more source
Scientific Reports, 2021 Api5, is a known anti-apoptotic and nuclear protein that is responsible for inhibiting cell death in serum-starved conditions. The only known post-translational modification of Api5 is acetylation at lysine 251 (K251).
Virender Kumar Sharma, Mayurika Lahiri
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Contribution of Nε-lysine Acetylation towards Regulation of Bacterial Pathogenesis
mSystems, 2021 Nε-lysine acetylation is an important, dynamic regulatory posttranslational modification (PTM) that is common in bacteria. Protein acetylomes have been characterized for more than 30 different species, and it is known that acetylation plays important ...
Jackson Luu, Valerie J. Carabetta
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Frontiers in Oncology, 2021 BackgroundLysine acetylation and deacetylation are posttranslational modifications that are able to link extracellular signals to intracellular responses. However, knowledge regarding the status of lysine regulators in urological cancers is still unknown.
Jian Zhang +4 more
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