Results 11 to 20 of about 199,012 (297)

Acetylation of Lysozyme

open access: bronzeAgricultural and Biological Chemistry, 1968
In order to elucidate the significance of amino groups as active groups of lysozyme, egg white lysozyme was acetylated with acetic anhydride. The acetylated lysozyme was fractionated by CM-cellulose column chromatography. All acetylated lysozymes fractionated exhibited 120% relative activity toward glycol chitin at pH 5.6, while the optimum pH shifted ...
Nobuyuki Yamasaki   +2 more
openalex   +5 more sources

The acetylation of insulin [PDF]

open access: yesBiochemical Journal, 1971
The acetylation of the free amino groups of insulin was studied by reaction of the hormone with N-hydroxysuccinimide acetate at pH6.9 and 8.5. The products formed were separated by chromatography on DEAE-Sephadex and were characterized by isoelectric focusing, by end-group analysis, by the incorporation of [3H]acetyl groups in the molecule, and by ...
Sydney Shall, D. G. Lindsay
openaire   +3 more sources

Acetylation Goes Global: The Emergence of Acetylation Biology [PDF]

open access: yesScience Signaling, 2009
Proteomic analysis shows protein acetylation to be more prevalent than previously appreciated.
Joo-Yong Lee   +2 more
openaire   +3 more sources

Acetylation of GATA4 on Lysine Residue K313 Promotes Osteoblastic Cells Growth

open access: yesCellular Physiology and Biochemistry, 2018
Background/Aims: GATA4, a protein related to osteoblast differentiation and mineralization, whose acetylation is essential for cardiac defects. Here, we aimed to explore the functional impacts of GATA4 acetylation on osteoporosis (OS).
Wenjun You, Lijuan Song, Kun Wang
doaj   +1 more source

Lysine acetylation decreases enzyme activity and protein level of Escherichia coli lactate dehydrogenase

open access: yesEngineering Microbiology, 2022
Lactate is an important bulk chemical with widespread applications and a major byproduct of other chemicals bioprocess in microbial fermentation. Lactate dehydrogenase A (LdhA) catalyzes the synthesis of lactate from pyruvate.
Min Liu   +7 more
doaj   +1 more source

Acetylation dynamics and stoichiometry in Saccharomyces cerevisiae

open access: yesMolecular Systems Biology, 2014
Lysine acetylation is a frequently occurring posttranslational modification; however, little is known about the origin and regulation of most sites.
Brian T. Weinert   +7 more
doaj   +1 more source

Protein Acetylation/Deacetylation: A Potential Strategy for Fungal Infection Control

open access: yesFrontiers in Microbiology, 2020
Protein acetylation is a universal post-translational modification that fine-tunes the major cellular processes of many life forms. Although the mechanisms regulating protein acetylation have not been fully elucidated, this modification is finely tuned ...
Junzhu Chen   +3 more
doaj   +1 more source

The interaction of canonical Wnt/β-catenin signaling with protein lysine acetylation

open access: yesCellular & Molecular Biology Letters, 2022
Canonical Wnt/β-catenin signaling is a complex cell-communication mechanism that has a central role in the progression of various cancers. The cellular factors that participate in the regulation of this signaling are still not fully elucidated.
Hongjuan You   +6 more
doaj   +1 more source

Non-enzymatic N-acetylation of Lysine Residues by AcetylCoA Often Occurs via a Proximal S-acetylated Thiol Intermediate Sensitive to Glyoxalase II

open access: yesCell Reports, 2017
Summary: Acetyl coenzyme A (AcCoA), a key intermediate in mitochondrial metabolism, N-acetylates lysine residues, disrupting and, in some cases, regulating protein function.
Andrew M. James   +6 more
doaj   +1 more source

Quantification of acetylated tubulin [PDF]

open access: yesCytoskeleton, 2013
The acetylation/deacetylation of Lys40 of the α‐subunit is an important posttranslational modification undergone by tubulin during the life of a cell. Many previous studies have addressed the physiological role of this acetylation process using various approaches based on changes of acetylated tubulin (AcTubulin) content.
Chesta, María Eugenia   +3 more
openaire   +4 more sources

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