Results 11 to 20 of about 204,757 (287)
Position-specific analysis and prediction for protein lysine acetylation based on multiple features. [PDF]
PLoS ONE, 2012 Protein lysine acetylation is a type of reversible post-translational modification that plays a vital role in many cellular processes, such as transcriptional regulation, apoptosis and cytokine signaling.
Sheng-Bao Suo +6 more
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Cells, 2022 Mitochondrial protein acetylation is associated with a host of diseases including cancer, Alzheimer’s, and metabolic syndrome. Deciphering the mechanisms regarding how protein acetylation contributes to disease pathologies remains difficult due to the ...
Courtney D. McGinnis +4 more
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Acetylation of GATA4 on Lysine Residue K313 Promotes Osteoblastic Cells Growth
Cellular Physiology and Biochemistry, 2018 Background/Aims: GATA4, a protein related to osteoblast differentiation and mineralization, whose acetylation is essential for cardiac defects. Here, we aimed to explore the functional impacts of GATA4 acetylation on osteoporosis (OS).
Wenjun You, Lijuan Song, Kun Wang
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Acetylation dynamics and stoichiometry in Saccharomyces cerevisiae
Molecular Systems Biology, 2014 Lysine acetylation is a frequently occurring posttranslational modification; however, little is known about the origin and regulation of most sites.
Brian T. Weinert +7 more
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Protein Acetylation/Deacetylation: A Potential Strategy for Fungal Infection Control
Frontiers in Microbiology, 2020 Protein acetylation is a universal post-translational modification that fine-tunes the major cellular processes of many life forms. Although the mechanisms regulating protein acetylation have not been fully elucidated, this modification is finely tuned ...
Junzhu Chen +3 more
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Engineering Microbiology, 2022 Lactate is an important bulk chemical with widespread applications and a major byproduct of other chemicals bioprocess in microbial fermentation. Lactate dehydrogenase A (LdhA) catalyzes the synthesis of lactate from pyruvate.
Min Liu +7 more
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Cell Reports, 2017 Summary: Acetyl coenzyme A (AcCoA), a key intermediate in mitochondrial metabolism, N-acetylates lysine residues, disrupting and, in some cases, regulating protein function.
Andrew M. James +6 more
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The interaction of canonical Wnt/β-catenin signaling with protein lysine acetylation
Cellular & Molecular Biology Letters, 2022 Canonical Wnt/β-catenin signaling is a complex cell-communication mechanism that has a central role in the progression of various cancers. The cellular factors that participate in the regulation of this signaling are still not fully elucidated.
Hongjuan You +6 more
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The role of protein acetylation in carcinogenesis and targeted drug discovery
Frontiers in Endocrinology, 2022 Protein acetylation is a reversible post-translational modification, and is involved in many biological processes in cells, such as transcriptional regulation, DNA damage repair, and energy metabolism, which is an important molecular event and is ...
Jingru Yang +4 more
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Conserved Lysine Acetylation within the Microtubule-Binding Domain Regulates MAP2/Tau Family Members. [PDF]
PLoS ONE, 2016 Lysine acetylation has emerged as a dominant post-translational modification (PTM) regulating tau proteins in Alzheimer's disease (AD) and related tauopathies.
Andrew W Hwang +6 more
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