Results 231 to 240 of about 301,703 (273)

Mechanisms of carbamate resistance in the malaria vector: <i>Anopheles gambiae</i>. [PDF]

Parasite Epidemiol Control
Cleanclay WD, Akanni MH, Bajepade TI, Ajeoge JK, Zakari S.   +4 more
europepmc   +1 more source

TNF‐α partially modulates the endothelial dysfunction during the acute phase of Trypanosoma cruzi infection

British Journal of Pharmacology, EarlyView.
Background and Purpose Whereas the effects of Trypanosoma cruzi (T. cruzi) infection are well‐characterised in the heart, its impact on the vasculature has received little attention. In this study, we investigated the effects of acute and chronic T. cruzi infection on vascular responsiveness and the underlying mechanisms.
Thales M. H. Dourado, Wanessa M. C. Awata, Gustavo F. Pimenta, Barbara M. Marchetti, Maiara V. Providello, Sérgio De Albuquerque, Carlos R. Tirapelli   +6 more
wiley   +1 more source

Vasomotor responses are similar between outbred UM-HET3 and inbred C57BL/6J male and female mouse mesenteric resistance arteries. [PDF]

Front Physiol
Looft-Wilson RC, Naraynan S, Salmon K, Wunibald E, Simmons B, Haitz C, Shah V, Xu M.   +7 more
europepmc   +1 more source

Opioids in breast cancer: Between analgesia and modulation of tumour progression

British Journal of Pharmacology, EarlyView.
Preclinical investigations consistently demonstrate that activation of μ‐opioid receptors and δ‐opioid receptors promote proliferation, migration, angiogenesis, epithelial‐mesenchymal transition, acquisition of cancer stem cell phenotypes, and chemoresistance.
Marianna Ciwun, Anna Tankiewicz‐Kwedlo, Dariusz Pawlak   +2 more
wiley   +1 more source

Novel drugs approved by the EMA, the FDA and the MHRA in 2025: A year in review

British Journal of Pharmacology, EarlyView.
Abstract In the 2025 novel drug mini‐review, one can take a full measure of the ingenuity that underlies current drug design and development, despite the year's smaller harvest (46 novel drugs) compared to 2024 (53) and 2023 (70). 54% of the novel drugs are first‐in‐class (FIC).
Andreas Papapetropoulos, Stavros Topouzis, Steve P. H. Alexander, Miriam M. Cortese‐Krott, Zsuzsanna Helyes, Kirill Martemyanov, Claudio Mauro, Nithyanandan Nagercoil, Reynold A. Panettieri Jr, Hemal H. Patel, Rainer Schulz, Barbara Stefanska, Gary J. Stephens, Nathalie Vergnolle, Xin Wang, Stephen Ward, Péter Ferdinandy   +16 more
wiley   +1 more source

Negative electrode degradation induced by two-stage zinc plating and its recovery in zinc batteries. [PDF]

Nat Commun
Gan H, Liu D, Zhang Y, Han C, Cheng HM.
europepmc   +1 more source

Invasive Diagnosis of HFpEF and ANOCA in a Patient With Effort Dyspnea and Angina. [PDF]

JACC Case Rep
Forzano I, Gargiulo G, Manzi L, Avvedimento M, Narciso V, Ciaramella L, Di Serafino L, Esposito G.   +7 more
europepmc   +1 more source

The effect of dexmedetomidine on rocuronium-induced neuromuscular blockade and its reversal by sugammadex. [PDF]

Intensive Care Med Exp
Fedor M, Sallai N, Fülesdi B, Fábián ÁI.   +3 more
europepmc   +1 more source

From Agro-Waste to Therapeutic Potential: Spasmolytic Mechanisms of <i>Vaccinium myrtillus</i> L. Leaf Extract on Isolated Rat Ileum. [PDF]

Plants (Basel)
Kitić N, Šavikin K, Kitić D, Jovanović M, Randjelović M, Živković J, Miladinović B, Ćujić Nikolić N, Stojiljković N, Branković S.   +9 more
europepmc   +1 more source