Results 91 to 100 of about 137,412 (311)

New N,N-dimethylcarbamate inhibitors of acetylcholinesterase: design synthesis and biological evaluation [PDF]

, 2016
A series of N,N-dimethylcarbamates containing a N,N-dibenzylamino moiety was synthesized and tested to evaluate their ability to inhibit Acetylcholinesterase (AChE).
Chiarotto, Isabella, Costi, Roberta, DE VITA, Daniela, DI SANTO, Roberto, Feroci, Marta, Ornano, Luigi, Pandolfi, Fabiana, Pepi, Federico, Scipione, Luigi, Sileno, Ilaria   +9 more
core   +1 more source

Engineered Metal–Organic Frameworks‐Based Materials for Environmental Detection

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
Engineered metal–organic frameworks (MOFs) regulated by various material modification strategies are discussed for environmental contaminant detection under different sensing mechanisms, providing future improvements of MOFs in environmental detection. Sensitive and selective detection of contaminants is crucial for environmental protection.
Pan Gao, Song Wang, Yuechao Yao, Yibo Dou   +3 more
wiley   +1 more source

Isolation of Three Lycorine Type Alkaloids from Rhodolirium speciosum (Herb.) Ravenna Using pH-Zone-Refinement Centrifugal Partition Chromatography and Their Acetylcholinesterase Inhibitory Activities

Metabolites, 2020
Preparative separation of three lycorine type alkaloids from Rhodolirum speciosum (Amaryllidaceae) was successfully carried out using pH-zone-refinement centrifugal partition chromatography (CPC) using the solvent system methyl-tert-butyl ether ...
Diana Isabel Correa, Edgar Pastene-Navarrete, Luis Bustamante, Marcelo Baeza, Julio Alarcón-Enos   +4 more
doaj   +1 more source

Status epilepticus: Updates on mechanisms and treatments

Epilepsia Open, EarlyView.
Abstract Status epilepticus (SE) consists of prolonged, self‐sustaining seizures and is a common neurological emergency that causes respiratory compromise and neuronal injury. Without prompt treatment, the seizures can become resistant to benzodiazepines, leading to the progressive evolution of established, refractory, and super‐refractory SE.
Suchitra Joshi, Jaideep Kapur
wiley   +1 more source

Acetylcholine Regulates Pulmonary Pathology During Viral Infection and Recovery

ImmunoTargets and Therapy, 2020
Alexander P Horkowitz,1,2 Ashley V Schwartz,3 Carlos A Alvarez,1,2 Edgar B Herrera,1 Marilyn L Thoman,1 Dale A Chatfield,4 Kent G Osborn,5 Ralph Feuer,2 Uduak Z George,3 Joy A Phillips1 1Donald P.
Horkowitz AP, Schwartz AV, Alvarez CA, Herrera EB, Thoman ML, Chatfield DA, Osborn KG, Feuer R, George UZ, Phillips JA   +9 more
doaj  

Acetylcholinesterase is not a generic marker of extracellular vesicles

Journal of Extracellular Vesicles, 2019
Acetylcholinesterase (AChE) activity is found in abundance in reticulocytes and neurons and was developed as a marker of reticulocyte EVs in the 1970s.
Zhaohao Liao, Lorena Martin Jaular, Estelle Soueidi, Mabel Jouve, Dillon C. Muth, Tine H. Schøyen, Tessa Seale, Norman J. Haughey, Matias Ostrowski, Clotilde Théry, Kenneth W. Witwer   +10 more
doaj   +1 more source

Discovery of pyrrole derivatives as acetylcholinesterase-sparing butyrylcholinesterase inhibitor [PDF]

, 2022
Shouyuan Sun, Tao Shi, Yan Peng, Honghua Zhang, Linsheng Zhuo, Peng Xue, Qien Li, Manxia Wang, Shuzhi Wang, Zhen Wang   +9 more
openalex   +1 more source

Synergistic Effect of Hesperidin, Acarbose, and Exercise Combination on Neuroinflammation and Neurochemical Alterations in Diabetic Encephalopathy Rat Model

Food Chemistry International, EarlyView.
Diabetic encephalopathy (DME) impairs neurobehavior, neurochemicals, oxidative stress, and inflammation. This study evaluated the effects of hesperidin (HSP), exercise (EX), and acarbose (ACA) alone or combined on diabetic rats. Treatments reduced AChE, BChE, ACE, arginase, ATPDase, 5′‐nucleotidase, ADA, LDH, TBARS, and ROS, while increasing IL‐10, SOD,
Idowu Sunday Oyeleye, Olajide Raymond Ojo, Taiwo Olawale Adeleke, Adeyinka Sunday Ajeigbe, Mercy Gladys Tenywa, Oboh Ganiyu   +5 more
wiley   +1 more source

Integrated Anatomical, Chemical, Biological and Computational Studies Approach of Myrcia sylvatica (G. Mey) DC. A Multifaceted Insight Into a Promising Amazonian Species

Flavour and Fragrance Journal, EarlyView.
This study presents an integrated anatomical, chemical, biological, and computational analysis of Myrcia sylvatica, revealing key bioactive compounds with antioxidant and toxicological potential, and identifying spathulenol and globulol as promising acetylcholinesterase inhibitors with favourable pharmacokinetic properties. ABSTRACT Myrcia sylvatica (G.
Eliza de Jesus Barros dos Santos, Zelina Ataíde Correia, Ely Simone Cajueiro Gurgel, Leonardo Souza da Costa, Mabrouk Horchani, Hayet Edziri, Ravendra Kumar, Anderson de Santana Botelho, Karyme do Socorro de Souza Vilhena, Eloisa Helena de Aguiar Andrade, Mozaniel Santana de Oliveira   +10 more
wiley   +1 more source

Stability and enzymatic studies with omeprazole: hydroxypropyl-β-cyclodextrin [PDF]

, 2010
The original publication is available at www.springerlink.com. A publicação original está disponível em www.springerlink.comOmeprazole (OME) exhibits low stability to light, heat and humidity.
A Hedges, B Ibach, C Salas, F Cheng, Fátima Fazão, G Zhao, H Marques, Helena Marques, L Marco, Luísa Serralheiro, M Abou-Donia, M Ahmed, M Arias, M Brewster, M Dewar, M Ruiz, Margarida Ramos, O Aleem, P Falé, P Houghton, P Mura, Paulo Salústio, R Hirlekar, S López, S Storpirtis, T Aihara, T Gubica, T Irie, T Loftsson, T Loftsson   +29 more
core   +1 more source