Results 101 to 110 of about 85,087 (299)

Short‐Term 6PPD‐Q Exposure alters Tight‐Junction‐Related Gene Expression Without Acute Lethality in Japanese Medaka Oryzias latipes

Journal of Applied Toxicology, EarlyView.
ABSTRACT 6PPD‐quinone (6PPD‐Q), a transformation product of the tire antioxidant 6PPD, causes acute mortality in several salmonid species, but its toxicity varies markedly among fish species. Disruption of vascular‐barrier integrity and inflammatory signaling has been proposed as a key mechanism of 6PPD‐Q toxicity.
Kyoshiro Hiki
wiley   +1 more source

Evaluation of Kinetic Parameters of Acetylcholinesterase from the Bovine Brain and its Inhibition with Mentha pulegium L. Extract

Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Īlām, 2020
Introduction: The function of acetylcholinesterase accelerates the acetylcholine hydrolysis process and protects the hemostasis of this neurotransmitter in the central nervous system and the peripheral tissues.
Maryam Mohadjerani, Arezo Rasolizadeh
doaj  

Comparison of acetylcholinesterase genes from cattle ticks

, 1999
We describe the isolation and characterisation of two putatively new acetylcholinesterase genes from the African cattle ticks Boophilus decoloratus and Rhipicephalus appendiculatus.
Barker, Stephen C., Baxter, Glenn D.
core   +1 more source

Artificial intelligence‐assisted nanozyme design for medical and environmental applications

Journal of Intelligent Medicine, EarlyView.
AI‐assisted nanozyme design integrates cross‐source data and machine learning to enable predictive structure‐activity relationships, accelerating intelligent diagnostics, precision therapeutics, and environmental surveillance. Abstract Nanozymes, a class of nanomaterials with intrinsic enzyme‐like catalytic activities, have emerged as promising ...
Xiaolin Guo, Hao Zhang, Zihan Zhao, Qingshan Liu, Jiayi Liu, Jiang Huang, Changlong Liu, Xiaoyu Mu   +7 more
wiley   +1 more source

Acetylcholinesterase-inhibitory activity of Iranian plants: Combined HPLC/bioassay-guided fractionation, molecular networking and docking strategies for the dereplication of active compounds

, 2018
In order to search for discovery of acetylcholinesterase (AChE) inhibitors, as a therapeutic strategy for treatment of the Alzheimer's disease, twenty-five Iranian plants have been evaluated by an in vitro enzymatic Ellman method and molecular docking ...
Danielle Skropeta (19584682), Celine Kelso (19588174), Ali Sonboli (536668), Mahdi Abbas-Mohammadi (1389753), Samad Nejad (20217519), Mahdi Moridi Farimani (15208003), Peyman Salehi (552031)   +6 more
core   +1 more source

Neuromuscular junction acetylcholinesterase deficiency responsive to albuterol

, 2012
Congenital myasthenic syndrome caused by endplate acetylcholinesterase deficiency constitutes a rare autosomal recessive disease. We describe a child with early-onset ptosis, complete ophthalmoplegia, facial and proximal muscle weakness, easy ...
Engel, Andrew G., Wong, Virginia C N, Chan, Sophelia H S   +2 more
core   +1 more source

Neuroprotective effects of quercetin in animal models of neurodegenerative diseases: A systematic review and meta‐analysis

Journal of the Science of Food and Agriculture, EarlyView.
Abstract Neurodegenerative conditions such as Alzheimer's disease and Parkinson's disease are characterized by progressive neuronal loss driven by oxidative stress and inflammation. Quercetin, a dietary flavonoid with established antioxidant and anti‐inflammatory properties, has emerged as a potential neuroprotective agent.
In Ho Cho, Hendra Mahakam Putra, Cheol Woon Jung, Gyu Hwan Hyun, Hwan‐Hee Jang, In Guk Hwang, Sung Won Kwon   +6 more
wiley   +1 more source

The Anti-Cholinesterase Potential of Fifteen Different Species of Narcissus L. (Amaryllidaceae) Collected in Spain

Life
Narcissus L. is a renowned plant genus with a notable center of diversity and is primarily located in the Mediterranean region. These plants are widely recognized for their ornamental value, owing to the beauty of their flowers; nonetheless, they also ...
Luciana R. Tallini, Giulia Manfredini, María Lenny Rodríguez-Escobar, Segundo Ríos, Vanessa Martínez-Francés, Gabriela E. Feresin, Warley de Souza Borges, Jaume Bastida, Francesc Viladomat, Laura Torras-Claveria   +9 more
doaj   +1 more source

Beyond a dual role: how Purpureocillium lilacinum reprograms citrus metabolism for integrated biocontrol and growth promotion

Journal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND Plants harbor complex microbial communities that are fundamental to their health and productivity. Among them, endophytic fungi such as Purpureocillium lilacinum establish mutualistic associations, offering dual benefits as plant growth promoters and biocontrol agents.
Sana Bouzembila, Kamel Charaabi, Haytham Hamden, Salma Fadhel, Nesrine Tanfouri, Meriem Msaad Guerfali   +5 more
wiley   +1 more source

Molecular properties of acetylcholinesterase

, 1978
This thesis describes the affinity purification of the enzyme acetylcholinesterase from the electric organ tissue of the electric eel (Electrophorus electricus) and the characterization of the enzyme by selective proteolytic cleavage monitored by sucrose
Webb, Geoffrey
core   +1 more source