Results 121 to 130 of about 85,087 (299)

J Am Mosq Control Assoc [PDF]

open access: yes
Insecticide resistance to organophosphates and carbamates can be the result of changes in acetylcholinesterase activity conferred by the ACE-1 mutation.

core  

Acetylcholinesterase Inhibitors: Pharmacology and Toxicology

open access: yes, 2013
Acetylcholinesterase is involved in the termination of impulse transmission by rapid hydrolysis of the neurotransmitter acetylcholine in numerous cholinergic pathways in the central and peripheral nervous systems.
Bondžić, Aleksandra M.   +5 more
core   +1 more source

Effects of bioinsecticide exposure route on aphids and their natural enemies in oilseed rape

open access: yesPest Management Science, EarlyView.
Fatty acids, silicone polymers and surfactants reduced aphid numbers but caused natural enemy mortality under direct exposure, while minimal residual activity suggests potential for targeted, compatible use in integrated pest management. Abstract BACKGROUND Myzus persicae Sulzer and Brevicoryne brassicae L.
Aimee J. Tonks   +3 more
wiley   +1 more source

Target‐site mutations and phenotypic failure in Myzus persicae against pyrethroids and carbamates in central Europe

open access: yesPest Management Science, EarlyView.
Molecular screening of 140 field‐collected Myzus persicae aphids revealed target‐site mutations L1014F, M918L, M918T, and L932F in the sodium channel and S431F in Ace2. The M918L mutation was the primary driver of high pyrethroid (cypermethrin) resistance, while S431F served as a definitive marker for carbamate (pirimicarb) resistance.
Jitka Stara   +3 more
wiley   +1 more source

MODELING AND STRUCTURAL ANALYSIS OF ACETYLCHOLINESTERASE ENZYME OF FISHES [PDF]

open access: yes, 2020
Objective: Computational studies on fish brain acetylcholinesterase were conducted, expanding our views and for a deeper understanding of the activity of the fish acetylcholinesterase enzyme.
PRAKASIA, PRESSY P.
core  

Methomyl resistance in Dalbulus maidis (Hemiptera: Cicadellidae): selection, inheritance and multiple‐resistance

open access: yesPest Management Science, EarlyView.
The inheritance of methomyl resistance in Dalbulus maidis is autosomal, incompletely dominant and polygenic. No cross‐resistance was found between methomyl and chlorfenapyr, cyantraniliprole and isocycloseram. Abstract BACKGROUND Acetylcholinesterase (AChE) inhibitor insecticides have been important tools for the management of Dalbulus maidis in Brazil;
Matheus Gerage Sacilotto   +3 more
wiley   +1 more source

Reduced fitness cost accounts for the stability of a malathion‐resistant heterogeneous duplication haplotype in Ceratitis capitata field populations

open access: yesPest Management Science, EarlyView.
Malathion resistance in Spanish field populations of Ceratitis capitata is associated with a point mutation (R allele) and a heterogeneous duplication (RS haplotype) of the Ccace2 gene. The R allele imposes a higher fitness cost than the RS haplotype under laboratory and field conditions. An evolutionary model supports the stability of the RS haplotype
Rabeh Arouri   +6 more
wiley   +1 more source

Intranasal diamorphine population pharmacokinetics modeling and simulation in pediatric breakthrough pain

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 435-447, March 2025.
Abstract Intranasal diamorphine (IND), approved for managing breakthrough pain in the UK, has been identified as an acceptable alternative offering effective, expedient, and less traumatic analgesia for children. However, the current dose regimen in pediatric populations relies on clinical expertise while the pharmacokinetics properties are poorly ...
Lianjin Cai   +6 more
wiley   +1 more source

Breaking Alzheimer's Disease Barrier: The Role of Xanthoceras sorbifolia Bunge Oil in Gut‐Brain Axis and TLR4/Myd88/MAPK Pathway Inhibition

open access: yesPhytotherapy Research, EarlyView.
ABSTRACT Alzheimer's disease (AD) is a progressive neurodegenerative disorder associated with cognitive decline and neuroinflammation. Xanthoceras sorbifolia Bunge oil (XSBO), a woody plant oil rich in bioactive fatty acids, has shown potential health benefits.
Lijing Du   +8 more
wiley   +1 more source

Ruta graveolens L. in Evidence‐Based Phytotherapy: Pharmacological Activities, Bioactive Compounds and Safety

open access: yesPhytotherapy Research, EarlyView.
Graphical representation of ethnomedical uses, major bioactive compounds, pharmacological potential and toxicological risks of Ruta graveolens L. ABSTRACT Ruta graveolens L. is widely used in traditional European, Asian, African, and South American medicine for digestive, nervous, cardiovascular, respiratory, and reproductive disorders.
Tetiana Serhiienko   +3 more
wiley   +1 more source

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