Results 131 to 140 of about 51,436 (262)
Halogen-dependent electronic regulation of reactivity and acetylcholinesterase recognition in halomethyl acetates: a predictive DFT-docking framework. [PDF]
Dahham Abed Abed M +4 more
europepmc +1 more source
Basil D. Roufogalis, Virginia M. Wickson
openaire +1 more source
Mapping Trofinetide Polypharmacology in Rett Syndrome: A Multi‐Stage Computational Analysis
How can a single molecule address the complex symptoms of Rett syndrome? This computational study maps the multi‐target mechanism of trofinetide, revealing diverse modes of binding across five key receptors: GAT1, GABAA, CHRM1, AMPA, and GSK3β. From deep orthosteric anchoring to dynamic surface interactions, these structural insights provide a rational
Luis Felipe Hernández‐Ayala +2 more
wiley +1 more source
Antioxidant, antimicrobial, and anticholinesterase activities of A. nitida leaf extract mediated silver nanoparticles. [PDF]
Zahoor M +5 more
europepmc +1 more source
Advances in enzymatic biofuel cells are highlighted through innovative electrode architectures, enzyme immobilization strategies, and hybrid integration with triboelectric, piezoelectric, and thermoelectric energy harvesters. These emerging approaches improve power output, operational stability, and biocompatibility, advancing self‐powered wearable and
Rashid Khan +3 more
wiley +1 more source
<i>Sparassis crispa</i> and a Bioactive Compound Therein, Ergosterol, Were Effective in Preventing Acetylcholinesterase Inhibition In Vitro and In Vivo. [PDF]
Park CK +13 more
europepmc +1 more source
Plasma P‐tau217 for detecting amyloid clearance after donanemab in Alzheimer's disease
Abstract INTRODUCTION This analysis of the phase 3 TRAILBLAZER‐ALZ 2 trial examined whether plasma tau protein phosphorylated at threonine 217 (p‐tau217) level can reliably monitor treatment‐related amyloid clearance (TRAC) after donanemab treatment in early symptomatic Alzheimer's disease (AD).
Emily C. Collins +5 more
wiley +1 more source
Effectiveness of Souvenaid® combined with acetylcholinesterase inhibitors on caregiver burden in Alzheimer´s disease. [PDF]
García-Alberca JM +3 more
europepmc +1 more source

