Results 81 to 90 of about 176,476 (335)

The Visually Related Posterior Pretectal Nucleus in the Non-Percomorph Teleost Osteoglossum bicirrhosum Projects to the Hypothalamus [PDF]

, 1991
This study was done to elucidate the ancestral (plesiomorphic) condition for visual pathways to the hypothalamus in teleost fishes. Three patterns of pretectal organization can be discerned morphologically and histochemically in teleosts. Their taxonomic
Baudelot, Bergquist, Braford, Brickner, Burr, Butler, Card, Catois, Ekström, Fritsch, Godement, Goldstein, Grover, Haller, Hendrickson, Herrick, Herrick, Holmgren, Honig, Ito, Ito, Kappers, Lauder, Luiten, Mayser, Mazzi, Meader, Mikkelsen, Moore, Moore, Murakami, Northcutt, Northcutt, Peter, Pickard, Pranz, Quinn, Rowe, Sakamoto, Schnitzlein, Sheldon, Striedter, Striedter, Swanson, Watts, Wullimann, Wullimann, Wullimann, Wullimann, Wullimann, Wullimann, Wullimann   +51 more
core   +1 more source

Indene-Derived Hydrazides Targeting Acetylcholinesterase Enzyme in Alzheimer’s: Design, Synthesis, and Biological Evaluation

Pharmaceutics, 2022
As acetylcholinesterase (AChE) plays a crucial role in advancing Alzheimer’s disease (AD), its inhibition is a promising approach for treating AD.
Shraddha Manish Gupta, Ashok Behera, Neetesh K. Jain, Devendra Kumar, Avanish Tripathi, Shailesh Mani Tripathi, Somdutt Mujwar, Jeevan Patra, Arvind Negi   +8 more
doaj   +1 more source

Cholinergic regulation of mood: from basic and clinical studies to emerging therapeutics. [PDF]

, 2019
Mood disorders are highly prevalent and are the leading cause of disability worldwide. The neurobiological mechanisms underlying depression remain poorly understood, although theories regarding dysfunction within various neurotransmitter systems have ...
Dulawa, Stephanie C, Janowsky, David S
core  

Use of Clotrimazole in Finfish Aquaculture: Mechanistic Insights, Limitations, and Future Directions for Antifungal Therapy

Animal Research and One Health, EarlyView.
This review critically evaluates clotrimazole as a potential antifungal for finfish aquaculture, highlighting strong mechanistic and in vitro efficacy against aquatic mycoses alongside major gaps in in vivo evidence, toxicokinetics, residue safety, and environmental risk, outlining priorities for responsible therapeutic development and regulatory ...
Arya Sen, Debashri Mondal, Thangapalam Jawahar Abraham   +2 more
wiley   +1 more source

Stability of acetylcholinesterase (AChE) activity in blood: the effect of the preservative agent

Archives of Forensic Medicine and Criminology
Fluoride anions are believed to inhibit acetylcholinesterase activity, thus there is a possibility that the activity may be affected by blood sampling into vials containing sodium fluoride as an ...
Kaja Tusiewicz, Paweł Szpot, Olga Wachełko, Marcin Zawadzki   +3 more
doaj   +1 more source

The relationship between deltamethrin-induced behavioral changes and acetylcholinesterase activity in zebrafish embryos or larvae based on transcriptome

Frontiers in Veterinary Science
BackgroundDeltamethrin (DM) is a broad-spectrum insecticide that is widely used to control agricultural pests. Recently, DM has posed a potential threat to the health of infants and young children, and this is because of the environmental and food ...
Chunyu Liu, Yantong Guo, Xue Zhang, Hongsong Chen, Maomao Han, Han Wang, Jieyao Niu, Jinfei He, Jingfeng Yang, Wu Dong, Jiangdong Xue   +10 more
doaj   +1 more source

Impact of Insecticides at Sublethal Concentrations on the Enzyme Activities in Adult Musca domestica L.

Toxics, 2023
Nowadays, the use of pesticides is, as before, the most common way to control arthropod plant pests and the ectoparasites of animals. The sublethal effects of pesticides on insects can appear at different levels, from genetics to populations, and the ...
Anna Kinareikina, Elena Silivanova
doaj   +1 more source

Latent acetylcholinesterase in secretory vesicles isolated from adrenal medulla [PDF]

, 1981
A new procedure is described for the preparation of highly purified and stable secretory vesicles from adrenal medulla. Two forms of acetylcholinesterase, a membrane bound form as well as a soluble form, were found within these vesicles.
Abbs, Anton, Bergmeyer, Blakeborough, Carty, Casey, Chubb, Chubb, Creutz, Dahl, Ekerdt, Ellman, Famborough, Farquar, Gratzl, Gratzl, Gratzl, Ingebretsen, Johnson, Laemmli, Lagercrantz, Leighton, Little, Lowry, Lowry, Meyer, Morris, Morris, Omaye, Palade, Rotundo, Rotundo, Schmidt, Smilowitz, Somogyi, Terland, Terland, Trifaro, Winkler   +38 more
core   +1 more source

Clinical pharmacology and prescribing education: An updated medical school curriculum from the British Pharmacological Society

British Journal of Clinical Pharmacology, EarlyView.
Aims Prescribing is a complex, essential skill that doctors must acquire to practice medicine safely and effectively. The British Pharmacological Society has historically provided a core curriculum to guide clinical pharmacology and prescribing education in UK medical schools.
Dagan O. Lonsdale, Clare Guilding, Jennifer Koenig, Michael Okorie, Reecha Sofat, Simon Maxwell   +5 more
wiley   +1 more source

4-Aminoquinoline-Based Adamantanes as Potential Anticholinesterase Agents in Symptomatic Treatment of Alzheimer’s Disease

Pharmaceutics, 2022
Considering that acetylcholinesterase (AChE) inhibition is the most important mode of action expected of a potential drug used for the treatment of symptoms of Alzheimer’s disease (AD), our previous pilot study of 4-aminoquinolines as potential human ...
Katarina Komatović, Ana Matošević, Nataša Terzić-Jovanović, Suzana Žunec, Sandra Šegan, Mario Zlatović, Nikola Maraković, Anita Bosak, Dejan M. Opsenica   +8 more
doaj   +1 more source