Results 241 to 250 of about 125,133 (347)

Light Sensitivity in Myasthenia Gravis: Clinical Characteristics and Impact on Quality of Life

open access: yesMuscle &Nerve, Volume 71, Issue 6, Page 1081-1085, June 2025.
ABSTRACT Introduction/Aims Light sensitivity is occasionally reported in myasthenia gravis patients, yet its prevalence, clinical characteristics, and impact on disease severity and quality of life remain insufficiently explored. This study aimed to evaluate the frequency, clinical characteristics, and the correlation of light sensitivity with ...
Eleonora Sabatelli   +7 more
wiley   +1 more source

Candidate Anxiety‐Related Genes in the Hippocampus of Hatano Male Rats: Anxiolytic Action of Neuromedin U in the Hippocampus

open access: yesNeuropsychopharmacology Reports, Volume 45, Issue 2, June 2025.
We screened for gene candidates in the hippocampus related to anxiety using Hatano high avoidance animals (HAA) and low avoidance animals (LAA), inbred rat strains that exhibit high and low levels of anxiety‐like behavior. The microarray analysis revealed differences in 498 gene expressions between HAA and LAA, of which nine genes conducted RT‐qPCR ...
Kaito Sato   +11 more
wiley   +1 more source

[18F]FE‐PE2I PET is a diagnostic tool in dementia with Lewy bodies

open access: yesPsychiatry and Clinical Neurosciences Reports, Volume 4, Issue 2, June 2025.
Our study showed that [18 F]FE‐PE2I PET represents a potential diagnostic tool with high accuracy in discriminating DLB patients from healthy controls, which is valuable for clinical practice. Abstract Aim Dementia with Lewy bodies (DLB) is characterized by motor and non‐motor symptoms. The degeneration of the dopaminergic pathway is a hallmark of DLB;
Andrea Sturchio   +7 more
wiley   +1 more source

Experimental methods for studying amyloid cross‐interactions

open access: yesProtein Science, Volume 34, Issue 6, June 2025.
Abstract Interactions between amyloid proteins represent the cornerstone of various pathogenic pathways, including prion conversion and co‐development of distinct kinds of systemic amyloidosis. Various experimental methodologies provide insights into the effects of such cross‐interactions on amyloid self‐assembly, which range from acceleration to ...
Aleksandra Kalitnik   +12 more
wiley   +1 more source

When is the optimal diagnostic biopsy timing of acetylcholinesterase staining in Hirschsprung disease? [PDF]

open access: yesBMC Pediatr
Koike Y   +9 more
europepmc   +1 more source

Target gene selection for sprayable dsRNA‐based biopesticide against Tetranychus urticae Koch (Acari: Tetranychidae)

open access: yesPest Management Science, Volume 81, Issue 6, Page 3055-3065, June 2025.
Silencing Prosbeta‐5 and Prosbeta‐1 resulted in high mortality in Tetranychus urticae, identifying them as potential target genes for double‐stranded RNA‐based biopesticides using spray‐induced gene silencing (SIGS). Abstract BACKGROUND Because of the excessive use of synthetic chemicals, the two‐spotted spider mite, Tetranychus urticae Koch, a highly ...
Yifei Wang   +10 more
wiley   +1 more source

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