ABSTRACT Duchenne muscular dystrophy (DMD) is an inherited neuromuscular disorder with multisystem involvement that causes progressive muscular weakness and cardiorespiratory dysfunction. The first comprehensive recommendations regarding anesthetic management are now almost 20 years old and, in the interval, DMD care has evolved.
Fabrizio Racca +4 more
wiley +1 more source
Neuroprotective potential of synthesized coumarin-based glycinate and heterocyclic amide derivatives: an acetylcholinesterase inhibition study. [PDF]
Farag B +6 more
europepmc +1 more source
Two distinct alcohol dehydrogenase classes mediate bacterial 2‐hydroxyethylphosphonate catabolism
Abstract Phosphonates are molecules containing a direct carbon‐phosphorus bond. In nature, these compounds are produced by a variety of organisms, and many environmental microbes are able to degrade specific phosphonates and feed on them. This work focuses on 2‐hydroxyethylphosphonate (HEP)—a natural compound that is found frequently in the environment,
Francesca Piazza +8 more
wiley +1 more source
Potential of <i>Aeginetia indica</i> for Alzheimer's Disease Management: In Vitro, In Vivo, and Computational Insights. [PDF]
Bhuiyan MR +10 more
europepmc +1 more source
Broadly expressed genes outperformed brain‐enriched neural targets as RNAi candidates in Halyomorpha halys. Microinjection of dsRNA targeting alpha‐soluble NSF attachment protein (Asnap) or Ras opposite protein (Rop) caused strong feeding suppression and near‐complete mortality, identifying them as promising targets for future oral or spray‐based RNAi ...
Nirakar Panda +2 more
wiley +1 more source
Magnetic Poly(VPA-co-EGDMA)-TiO<sub>2</sub> Polymeric Microspheres as Supports for Acetylcholinesterase Immobilization: Kinetic Behavior, Stability, and Reusability. [PDF]
Özel Ş.
europepmc +1 more source
ABSTRACT Bisphenol A (BPA), a common industrial chemical used in plastics and consumer products, is increasingly detected in aquatic environments, raising serious concerns about its potential ecological impacts. This study evaluated the sublethal and acute toxic effects of BPA on the freshwater planarian Girardia tigrina, a recognized model for ...
Raquel de Jesus Selestrino +2 more
wiley +1 more source
Correction: Satapathy et al. Solid Lipid Nanoparticles (SLNs): An Advanced Drug Delivery System Targeting Brain Through BBB. <i>Pharmaceutics</i> 2021, <i>13</i>, 1183. [PDF]
Satapathy MK +6 more
europepmc +1 more source
Separating the effects of temperature and absorbed X‐ray dose on unit‐cell volume
The nature of the expansion of the crystal unit‐cell volume with absorbed dose and with temperature was examined for three different proteins.The behaviour of the unit‐cell volume of crystals of the iron‐storage molecule ferritin, both in the apo and the holo form, and of influenza A virus subtype N9 neuraminidase at 100 K and over a controlled cryo ...
Robert J. Southworth-Davies +5 more
wiley +1 more source
Dietary CoQ10 improves megakaryocyte maturation and polyploidization and reduces platelet hyperreactivity in naturally aged mice, while experiments in senescent Meg‐01 cells demonstrate enhanced autophagic flux and identify COPS3 as a contributing, but not, mediator.
Yixuan Xu +9 more
wiley +1 more source

