Results 41 to 50 of about 133,708 (320)

Binding of acetylcholinesterases to concanavalin A [PDF]

open access: yesFEBS Letters, 1974
Acetylcholinesterases from a number of different sources are known to be glycoproteins. Carbohydrate residues were found in the eel enzyme [ 1,2] , human erythrocyte acetylcholinesterase [3 ] torpedo California [4] plaice cholinesterase [ 51 and the cholinesterases from human serum [6,7], horse serum [8,9] and human brain [lo]. It was of interest to us
R. Gentinetta   +2 more
openaire   +2 more sources

A Comparison of the Potency of the Oxime HLö-7 and Currently Used Oximes (HI-6, Pralidoxime, Obidoxime) to Reactivate Nerve Agent-Inhibited Rat Brain Acetylcholinesterase by in vitro Methods

open access: yesActa Medica, 2005
1. The efficacy of the oxime HLö-7 and currently used oximes (pralidoxime, obidoxime, HI-6) to reactivate acetylcholinesterase inhibited by various nerve agents (sarin, tabun, cyclosarin, VX) was tested by in vitro methods. 2. Both H oximes (HLö-7, HI-6)
Kamil Kuča   +4 more
doaj   +1 more source

New substrates of acetylcholinesterase [PDF]

open access: yesFEBS Letters, 1981
Volume 134, number 1 FEBS LETTERS November 1981 NEW SUBSTRATES OF ACETYLCHOLINESTERASE Meira NAVEH, Zmira BERNSTEIN, Dina SEGAL and Yechiel SHALITIN* Department of Biology, Technion-Israel Institute of Technology, Haifa, 32000, Israel Received 2 September 1981 1.
Dina Segal   +3 more
openaire   +3 more sources

Combining In Silico and In Vitro Studies to Evaluate the Acetylcholinesterase Inhibitory Profile of Different Accessions and the Biomarker Triterpenes of Centella asiatica

open access: yesMolecules, 2020
Alzheimer’s disease (AD) is a neurodegenerative disease and the most cause of dementia in elderly adults. Acetylcholinesterase (AChE) is an important beneficial target for AD to control cholinergic signaling deficit.
Nor Atiqah Jusril   +4 more
doaj   +1 more source

Neurotoxicity [PDF]

open access: yes, 2014
Neurotoxicity refers to the direct or indirect effect of chemicals that disrupt the nervous system of humans or animals. Numerous chemicals can produce neurotoxic diseases in humans, and many more are used as experimental tools to disturb or damage the ...
Brust   +15 more
core   +2 more sources

Serum cholinesterases are differentially regulated in normal and dystrophin-deficient mutant mice

open access: yesFrontiers in Molecular Neuroscience, 2012
The cholinesterases, acetylcholinesterase and butyrylcholinesterase (pseudocholinesterase), are abundant in the nervous system and in other tissues. The role of acetylcholinesterase in terminating transmitter action in the peripheral and central nervous ...
Andrea R. Durrant   +2 more
doaj   +1 more source

Extraction of Antioxidants from Winemaking Byproducts: Effect of the Solvent on Phenolic Composition, Antioxidant and Anti-Cholinesterase Activities, and Electrochemical Behaviour

open access: yesAntioxidants, 2020
Extraction solvent is a very important factor in the recovery of antioxidants from natural matrices. In this study, the effect of three solvents (ethanol, ethanol/water and water) on the phenolic composition, antioxidant and anti-cholinesterase ...
María José Jara-Palacios   +4 more
doaj   +1 more source

Acetylcholinesterase inhibitors for schizophrenia [PDF]

open access: yesEuropean Psychiatry, 2009
IntroductionAs evidenced by ongoing research and partial effectiveness of the antipsychotics on cognitive and negative symptoms, the search is on for drugs that may improve these domains of functioning for someone suffering from schizophrenia.ObjectivesTo do a sytematic review to find out if acetylcholinesterase inhibitors could be used for ...
Jasvinder A. Singh   +2 more
openaire   +4 more sources

Acetylcholinesterase Inhibitors in the Treatment of Neurodegenerative Diseases and the Role of Acetylcholinesterase in their Pathogenesis [PDF]

open access: yesInternational Journal of Molecular Sciences, 2021
Acetylcholinesterase (AChE) plays an important role in the pathogenesis of neurodegenerative diseases by influencing the inflammatory response, apoptosis, oxidative stress and aggregation of pathological proteins. There is a search for new compounds that can prevent the occurrence of neurodegenerative diseases and slow down their course.
Łucja Justyna Walczak-Nowicka   +1 more
openaire   +3 more sources

The Effect of Parathion on Red Blood Cell Acetylcholinesterase in the Wistar Rat

open access: yesJournal of Toxicology, 2016
Organophosphorus (OP) pesticide poisoning is a significant problem worldwide. Research into new antidotes for these acetylcholinesterase inhibitors, and even optimal doses for current therapies, is hindered by a lack of standardized animal models.
Naofumi Bunya   +3 more
doaj   +1 more source

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