Results 81 to 90 of about 67,911 (287)

When manual disimpaction isn't enough: Case report and review of neostigmine's role in refractory constipation management

open access: yesJPGN Reports, EarlyView.
ABSTRACT Severe refractory constipation can lead to fecal retention requiring hospitalization, nasogastric cleanout, or manual disimpaction, and in some cases, surgery. Neostigmine, a reversible acetylcholinesterase inhibitor, is commonly used for pseudo‐obstruction but rarely for refractory constipation. Here, we report a 21‐year‐old male with chronic
Mojdeh Mostafavi   +2 more
wiley   +1 more source

The Anti-Cholinesterase Potential of Fifteen Different Species of Narcissus L. (Amaryllidaceae) Collected in Spain

open access: yesLife
Narcissus L. is a renowned plant genus with a notable center of diversity and is primarily located in the Mediterranean region. These plants are widely recognized for their ornamental value, owing to the beauty of their flowers; nonetheless, they also ...
Luciana R. Tallini   +9 more
doaj   +1 more source

Basal Forebrain Volume Predicts Disease Conversion in Prodromal Synucleinopathy

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Isolated rapid eye movement sleep behavior disorder (iRBD) is a prodromal stage of Parkinson's disease (PD) and dementia with Lewy bodies (DLB). The basal forebrain (BF), a key cholinergic structure, is a site of known pathology in later stages of Lewy body disorders.
Lachlan Churchill   +5 more
wiley   +1 more source

Considerations for Initiation and Maintenance of Foslevodopa/Foscarbidopa for Advanced Parkinson's Disease

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background As Parkinson's disease (PD) progresses, motor fluctuations become increasingly difficult to manage with oral medications. Foslevodopa/foscarbidopa (LDp/CDp), delivered as a continuous 24‐h/day subcutaneous infusion, offers continuous levodopa delivery and stable plasma levodopa levels that reduce motor fluctuations. LDp/CDp has been
K. Ray Chaudhuri   +20 more
wiley   +1 more source

Post Hoc, Sex‐Specific Subgroup Analysis of Efgartigimod in Patients With Generalized Myasthenia Gravis From the ADAPT Trial: A Sex and Gender Equity in Research (SAGER) Guidelines Approach

open access: yesMuscle &Nerve, EarlyView.
ABSTRACT Introduction/Aims Sex‐specific differences in myasthenia gravis (MG) are widely acknowledged, yet data on sex‐based outcomes of MG treatment are scarce. In accordance with Sex and Gender Equity in Research guidelines, this post hoc analysis assessed potential sex‐specific differences in treatment outcomes in acetylcholine receptor antibody ...
Sarah Hoffmann   +5 more
wiley   +1 more source

Modifying Antibiotic Activity of Synthetic Thiadiazine Analogs Against MDR Bacteria and ADMET Analysis

open access: yesChemistryOpen, EarlyView.
The study demonstrated that thidiazine compounds potentiated the action of antibiotics. The compounds associated with norfloxacin against S. aureus showed greater significance in relation to the other medications. The indiscriminate use of antibiotics has led to the selection of resistant bacterial strains, significantly reducing the effectiveness of ...
João Arthur de Oliveira Borges   +15 more
wiley   +1 more source

Evolving resistance patterns in Tetranychus urticae and Bemisia tabaci in Greece

open access: yesPest Management Science, EarlyView.
Greek populations of T. urticae and B. tabaci exhibit evolving multi‐resistance, confirmed by bioassays and molecular markers, highlighting the urgent need for evidence‐based resistance monitoring in IPM. Abstract BACKGROUND Pesticide resistance in agricultural pests remains a major barrier to effective and sustainable crop protection.
Anastasia Kampouraki   +8 more
wiley   +1 more source

Pesticide prioritization based on risk and model diet proposals for assessing cumulative exposure to pesticide residues in the Brazilian population through food consumption

open access: yesPest Management Science, EarlyView.
A risk classification of registered pesticides in Brazil was conducted, and the contribution of food to cumulative pesticide exposure was evaluated. Model diets were proposed, based on Brazilian consumption patterns. Abstract BACKGROUND Pesticide residue exposure assessments can be carried out during both the pre‐regulation and post‐regulation phases ...
Bianca Figueiredo de Mendonça Pereira   +1 more
wiley   +1 more source

Effects of bioinsecticide exposure route on aphids and their natural enemies in oilseed rape

open access: yesPest Management Science, EarlyView.
Fatty acids, silicone polymers and surfactants reduced aphid numbers but caused natural enemy mortality under direct exposure, while minimal residual activity suggests potential for targeted, compatible use in integrated pest management. Abstract BACKGROUND Myzus persicae Sulzer and Brevicoryne brassicae L.
Aimee J. Tonks   +3 more
wiley   +1 more source

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