Results 81 to 90 of about 176,114 (393)

Filamented Light (FLight) Bioprinting of Mini‐Muscles with Self‐Renewal Potential

open access: yesAdvanced Materials, EarlyView.
This work presents the FLight biofabrication for engineering in vitro muscle constructs by photocrosslinking pristine collagen and fibrinogen using ruthenium. The resulting mini‐muscles retain in vivo‐like tissue organization and a Pax7⁺ cell pool.
Hao Liu   +8 more
wiley   +1 more source

Prospective Application of Two New Pyridine-Based Zinc (II) Amide Carboxylate in Management of Alzheimer’s Disease: Synthesis, Characterization, Computational and in vitro Approaches

open access: yesDrug Design, Development and Therapy, 2021
Rehman Zafar,1,2 Humaira Naureen,3 Muhammad Zubair,4 Khadija Shahid,1 Muhammad Saeed Jan,5 Samar Akhtar,2 Hammad Ahmad,2 Wajeeha Waseem,6 Ali Haider,4 Saqib Ali,4 Muhammad Tariq,7 Abdul Sadiq8 1Department of Pharmaceutical Chemistry, Faculty of ...
Zafar R   +11 more
doaj  

Anti-Cholinesterase Activity of Lycopodium Alkaloids from Vietnamese Huperzia squarrosa (Forst.) Trevis

open access: yesMolecules, 2014
A series of Lycopodium alkaloids, namely lycosquarosine A (1), acetylaposerratinine (2), huperzine A (3), huperzine B (4), 8α-hydrophlemariurine B (5), and huperzinine (6), has been isolated from Vietnamese Huperzia squarrosa.
Nguyen Ngoc Chuong   +3 more
doaj   +1 more source

Protective effect of Allium atroviolaceum-synthesized SeNPs on aluminum-induced brain damage in mice

open access: yesOpen Chemistry, 2022
This study evaluated the possible neuroprotective effect of Allium atroviolaceum extract (AaE)-synthesized selenium nanoparticles (SeNPs) on aluminum (Al)-induced neurotoxicity in mice, explaining the likely mechanisms. Mice were divided into five groups:
Othman Mohamed S.   +11 more
doaj   +1 more source

Demonstration of astrocytes in cultured amniotic fluid cells of three cases with neural-tube defect [PDF]

open access: yes, 1981
We have investigated the origin of rapidly adhering (RA) cells in three cases of neural tube defects (two anencephali, one encephalocele). We were able to demonstrate the presence of glial fibrillary acidic (GFA) protein in variable percentages (4–80 ...
AD Smith   +18 more
core   +1 more source

Harnessing Photo‐Energy Conversion in Nanomaterials for Precision Theranostics

open access: yesAdvanced Materials, EarlyView.
Harnessing photo‐energy conversion in nanomaterials enables precision theranostics through light‐driven mechanisms such as photoluminescence, photothermal, photoelectric, photoacoustic, photo‐triggered surface‐enhanced Raman scattering (SERS), and photodynamic processes. This review explores six fundamental principles of photo‐energy conversion, recent
Jingyu Shi   +4 more
wiley   +1 more source

Macrophage TNF-α mediates parathion-induced airway hyperreactivity in guinea pigs. [PDF]

open access: yes, 2013
Organophosphorus pesticides (OPs) are implicated in human asthma. We previously demonstrated that, at concentrations that do not inhibit acetylcholinesterase activity, the OP parathion causes airway hyperreactivity in guinea pigs as a result of ...
Allison D. Fryer   +12 more
core   +1 more source

Rewiring Neuroimmunity: Nanoplatform Innovations for CNS Disease Therapy

open access: yesAdvanced Therapeutics, EarlyView.
This review explores emerging nanoplatform strategies designed to modulate neuroimmune responses for treating central nervous system (CNS) disorders. It examines structural and microenvironmental barriers, advances in multifunctional and targeted nanotechnologies, and highlights clinical progress and translational challenges, offering insights into the
Muhammad Usman Akbar   +7 more
wiley   +1 more source

Sleep Deprivation Aggravates Periodontitis Through Trigeminal‐Periodontal Neuroimmune Pathway Mediated by the AChE‐ACh‐α7nAChR Axis

open access: yesAdvanced Science, EarlyView.
Sleep deprivation (SD) exacerbates ligature‐induced periodontitis (LIP) through the trigeminal nerve‐periodontal neuroimmune pathway mediated by the acetylcholinesterase (AChE)‐acetylcholine (ACh)‐α7 nicotinic receptor (α7nAChR) axis. While electroacupuncture (EA) alleviates the condition of LIP combined with SD by activating the α7nAChR.
Kehao Liu   +13 more
wiley   +1 more source

AIEgen‐Based and Smartphone‐Assisted On‐Site Quantitation of Cystatin C for Monitoring of Chronic Kidney Disease

open access: yesAggregate, EarlyView.
By employing new protein‐templated AIEgen Ir@BSA as the phosphorescence signal indicator and papain as the biomolecular recognition element, a straightforward protocol for Cys C quantitation has been developed. On‐site quantitation of Cys C in clinical serum samples has been successfully demonstrated using a smartphone‐based portable phosphorescence ...
Shuqi Xia   +7 more
wiley   +1 more source

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