Results 101 to 110 of about 40,317 (191)

Restoration of Immune Surveillance in Prostate Cancer Prevention by Sulforaphane in Hi‐Myc Mice

Molecular Carcinogenesis, Volume 65, Issue 6, Page 677-686, June 2026.
ABSTRACT Oral administration of broccoli constituent sulforaphane (SFN) prevents prostate cancer development in preclinical mouse models. However, the mechanism(s) underlying prostate cancer prevention by SFN are not fully understood. In this study, we used a human relevant mouse model (Hi‐Myc mice) to demonstrate restoration of immune surveillance by ...
Krishna B. Singh, Eun‐Ryeong Hahm, Joshi J. Alumkal, Shivendra V. Singh   +3 more
wiley   +1 more source

Glycine and N-acetylcysteine supplementation, with or without exercise, in brain health and functional aging: implications for sarcopenia and frailty in older adults. [PDF]

Front Nutr
Wang X, Hou R, Chen Z, Wang X, Wang H.
europepmc   +1 more source

Targeting Mitochondria in Aging‐Related Diseases: Therapeutic Potential and Obstacles

MedComm, Volume 7, Issue 6, June 2026.
This article systematically summarized the specific mechanism of aging‐related diseases caused by mitochondrial dysfunction, and summarized the broad‐spectrum treatment methods and disease targeted treatment strategies for mitochondria. At the same time, it also pointed out the dilemma faced by mitochondrial targeted treatment.
Zijie Xiang, Yu Chen, Xishui Liu, Haowen Lu, Yuqing Yang, Lei Xing, Yu Zhang, Chuandong Lang, Siming Zhang, Shixiang Zhao, Youzhi Hong, Jiaxiang Bai, Yusen Qiao   +12 more
wiley   +1 more source

Performance of New Roche Cobas Pulse Glucose Meter Against Potential Interfering Substances and Hematocrit Variations. [PDF]

Diagnostics (Basel)
Pudineh Moarref M, Black W, Chen Y.
europepmc   +1 more source

Redox Regulation and Oxidative Stress in Health and Disease: Mechanisms and Therapeutic Targeting

MedComm – Future Medicine, Volume 5, Issue 2, June 2026.
Reactive species serve crucial roles which are tightly regulated in both physiological as well as disease states. At physiological levels, these species are integral to redox signaling, while uncontrolled redox promotes disease pathology. This review examines the dysregulation of these processes.
Mohammad Hossein Azadi, Azadeh Niknejad, Elaheh Amini   +2 more
wiley   +1 more source

N-acetylcysteine nano-spray versus conventional treatment in the management of radiotherapy-induced oral mucositis in oral cancer patients: a randomized clinical trial. [PDF]

BMC Oral Health
Essam A, Domiaty SE, Attia N, Helal H, Meheissen M.   +4 more
europepmc   +1 more source

Oxidative Stress in the Tumor Immune Microenvironment: Mechanisms and Therapeutic Perspectives

MedComm – Oncology, Volume 5, Issue 2, June 2026.
Oxidative stress is involved in several key processes in cancer, including redox regulation, DNA damage, post‐translational modifications, transcriptional regulation, epigenetic modifications, metabolic reprogramming, cell death, and immune modulation. These mechanisms collectively influence tumor progression, immune evasion, and therapeutic responses,
Zhen Wang, Bowen Li, Pan Tang, Fanchen Yan, Shuxin Wang, Guiying Leng, Panduo Dawa, Yuansi Chen, Yihan Guo, Pan Yang, Yi Li, Siyu Liu, Erdan Dong, Siyuan Qin, Zhoufeng Wang   +14 more
wiley   +1 more source

N-Acetylcysteine Reduces Alveolar Bone Loss and Mitigates Systemic Oxidative Damage in Rats With Apical Periodontitis. [PDF]

Int Endod J
Dos Santos IWR, Souza-Monteiro D, Frazão DR, da Silva ZAL, de Moura JDM, Cruz JN, Collares FM, de Souza-Rodrigues RD, Cintra LTÂ, Lima RR.   +9 more
europepmc   +1 more source

Glutathione‐Related Metabolite Levels and Enzyme Activities in Depression: A Systematic Review and Meta‐Analysis

Neuropsychopharmacology Reports, Volume 46, Issue 2, June 2026.
We conducted a systematic review and meta‐analysis to compare the levels of glutathione‐related metabolites. Our meta‐analysis indicated significantly decreased activity of glutathione‐peroxidase in patients with depression compared with healthy controls, while the levels of glutathione and glutathione reductase were not significantly different between
Takahide Etani, Nobuaki Hondo, Sho Moriguchi, Kazunari Yoshida, Sotaro Moriyama, Koki Takahashi, Tahichi Moritake, Yumina Nakamura, Ryoma Kani, Shiori Honda, Masataka Wada, Sakiko Tsugawa, Yukino Mori, Hikari Segawa, Tony Kaku, Hiroyuki Uchida, Shinichiro Nakajima   +16 more
wiley   +1 more source

Nicotinamide adenine dinucleotide inhibits the production of reactive oxygen species and myocardial cell pyroptosis caused by hypoxia/re-oxygenation injury. [PDF]

World J Cardiol
Dong S, Liu YQ, Tu YJ, Gao S, Liu YJ, Liu C, Pei ZW.   +6 more
europepmc   +1 more source