PSO exhibited protective effects against CSE‐induced pulmonary inflammation by reducing macrophage and eosinophil infiltration, preventing alveolar destruction, and enhancing antioxidant defense by lowering serum MDA levels in a murine COPD model. These findings support the potential role as a dietary supplement for the prevention or attenuation of ...
Gaewarin Liamvilairat +5 more
wiley +1 more source
Epstein-Barr Virus (EBV) Hepatitis Treated With N-Acetylcysteine: Placebo Versus True Effect. [PDF]
Ahl A, Abadir S, Kalfayan G, Desai K.
europepmc +1 more source
Cobinamide, a Vitamin B<sub>12</sub> Analog, Attenuates Benzo[a]pyrene and Pyrene Toxicity Through Selective Redox Modulation. [PDF]
Kalyanaraman A +9 more
europepmc +1 more source
N6‐Methyladenosine (m6A) in Liver Disease: Pathogenic Mechanisms and Therapeutic Potential
ABSTRACT Accumulating evidence highlights the critical role of epigenetic modifications, particularly N6‐methyladenosine (m6A), in liver disease. As the most abundant RNA modification in eukaryotic cells, m6A is dynamically regulated by multicomponent m6A methyltransferases (e.g., METTL3 and METTL14), demethylases (FTO and ALKBH5), and m6A‐binding ...
Yingfen Chen +6 more
wiley +1 more source
N-Acetylcysteine Reduces Tissue Injury Induced by Oxygen-Glucose Deprivation in an Organotypic Culture of Mouse Cerebral Cortex Slices. [PDF]
Villani C +3 more
europepmc +1 more source
ABSTRACT Background Ceramides have garnered considerable attention as pro‐aging bioactive lipids implicated in both metabolic dysfunction and musculoskeletal decline. Among these, C18:0 and C24:1 ceramides may play a role in the pathophysiology of sarcopenia, a key manifestation of age‐related deterioration.
So Jeong Park +15 more
wiley +1 more source
N-Acetylcysteine Prevents Arsenic-Induced Apoptosis but Not Supernumerary Motor Neuron Development in Zebrafish Embryos: Assessment of Protein Carbonylation and the p53 Pathway. [PDF]
Gu Q +4 more
europepmc +1 more source
Stimuli‐Responsive Poly(Disulfide)s: A Versatile Platform for Intelligent Drug Delivery Systems
Ring‐opening polymerization based on dynamic disulfide bond exchange is an important method for synthesizing poly(disulfide)s. These polymers possess stimulus‐responsive mechanisms and show broad prospects in intelligent drug delivery. This review systematically discusses the ring‐opening polymerization strategy and research progress of drug delivery ...
Yuechen He +7 more
wiley +1 more source
Efficacy and safety of N-acetylcysteine in patients with mild cognitive impairment undergoing exercise-based cardiac rehabilitation program: a randomized controlled trial. [PDF]
Gallagher D +17 more
europepmc +1 more source

