Results 171 to 180 of about 88,160 (292)

Pulmonary impact of N-acetylcysteine in a controlled hemorrhagic shock model in rats

, 2012
Karen Ruggeri Saad, Paulo Fernandes Saad, Luiz Dantas de Oliveira Filho, Jôse Mára de Brito, Márcia Kiyomi Koike, Fernando Luiz Zanoni, Marisa Dolhnikoff, Edna Frasson de Souza Montero   +7 more
openalex   +1 more source

Farnesol in combination with N-acetylcysteine against Staphylococcus epidermidis planktonic and biofilm cells [PDF]

, 2012
Fernanda Gomes, Bruna Leite, P. Teixeira, Joana Azeredo, Rosário Oliveira   +4 more
openalex   +1 more source

Drug Repurposing Screen Identifies Pimozide as a ROS‐Inducing Therapy With Anti‐Tumor Efficacy in HNSCC PDX Models

Cancer Science, EarlyView.
A drug repurposing screen for reactive oxygen species (ROS)‐inducing compounds identified Pimozide as a potent anti‐tumor agent in head and neck squamous cell carcinoma (HNSCC) patient‐derived xenograft (PDX) models. Combined treatment with paclitaxel markedly reduced undifferentiated tumor cells.
Shogo Okazaki, Shintaro Nakamura, Tomoya Soma, Momoko Yoshikawa, Seiji Asoda, Yurika Nakajima, Kenji Tsuchihashi, Mitsuyo Ohmura, Ryo Goitsuka, Kenichi Imai, Hideyuki Saya, Osamu Nagano, Hiroyuki Ozawa   +12 more
wiley   +1 more source

Melatonin and N-acetylcysteine influence on the lipoperoxidation intensity in blood serum and central nervous system of rats with type 1 diabetes mellitus

, 2018
О. А. Фіцнер, M.V. Кhaitovych, T. S. Briuzghina   +2 more
openalex   +2 more sources

N-Acetylcysteine Supplementation Controls Total Antioxidant Capacity, Creatine Kinase, Lactate, and Tumor Necrotic Factor-Alpha against Oxidative Stress Induced by Graded Exercise in Sedentary Men [PDF]

, 2011
Donrawee Leelarungrayub, Raphiphat Khansuwan, Prapas Pothongsunun, Jakkrit Klaphajone   +3 more
openalex   +1 more source

In‐Tumor CRISPR‐Cas9 Knockout Screening and Novel Therapy Development for Malignant Transformation of Ovarian Teratoma

Cancer Science, EarlyView.
We conducted an in vivo genome‐wide CRISPR‐Cas9 knockout screen using MTMCT‐derived cells to identify genes essential for tumor growth. SOD1 emerged as a key therapeutic target, and its inhibition suppressed tumor proliferation by disrupting redox homeostasis, both in vitro and in PDX models. ABSTRACT Malignant transformation of mature cystic teratoma (
Satoshi Tamauchi, Kosuke Yoshida, Wang Xinyuan, Atsushi Nakagawa, Akira Yokoi, Nobuhisa Yoshikawa, Kaoru Niimi, Yusuke Yamamoto, Hiroaki Kajiyama   +8 more
wiley   +1 more source

Effects of acetylcysteine combined with bronchoalveolar lavage under fiberoptic bronchoscopy on blood oxygenation and inflammation in elderly severe pneumonia patients. [PDF]

Am J Transl Res
Wu Y, Yao J, Zhang Y.
europepmc   +1 more source

PIK‐III‐Mediated Elevation of Thiamine Re‐Sensitises Renal Cell Carcinoma to Cuproptosis via Activating PDHA1

Cell Proliferation, EarlyView.
PIK‐III enhancing the efficacy of cuproptosis to kill renal cancer cells through dysregulating thiamine metabolism and dephosphorylation of pyruvate dehydrogenase complex E1 (PDHA1), providing a potential option for treatment of cuproptosis‐resistant renal cancer by the combination of PIK‐III and elesclomol.
Dongdong Xie, Yu Wang, Wenjie Cheng, Minbo Yan, Kunyu Li, Xiang Wu, Jiaqing Wu, Zhuangzhuang Zhang, Yingbo Dai   +8 more
wiley   +1 more source

N-Acetylcysteine Attenuates Cisplatin-Induced Acute Kidney Injury by Inhibiting the C5a Receptor [PDF]

, 2019
Shuai Huang, Jian You, Kun Wang, Yueqiang Li, Ying Zhang, Haotian Wei, Xinjun Liang, Yanyan Liu   +7 more
openalex   +1 more source

Successful use of haemoperfusion therapy in an adult horse with hepatic encephalopathy and cholangiohepatitis

Equine Veterinary Education, EarlyView.
Summary A 4‐year‐old, 520 kg, American Quarter Horse broodmare, approximately 90 days in foal, was presented to Texas A&M University Teaching Hospital for suspected liver disease. Based on clinicopathological values and hepatic abnormalities noted ultrasonographically, the mare was presumptively diagnosed with cholangiohepatitis.
A. C. Trimble, S. H. White‐Springer, S. Alpini, E. Rumfola, A. N. DiSilvestro, Y. Ueda, K. Hobbs   +6 more
wiley   +1 more source