Results 131 to 140 of about 91,412 (386)

Functional implications of structural homologies between chloramphenicol acetyltransferase and dihydrolipoamide acetyltransferase [PDF]

FEMS Microbiology Letters, 1987
Comparisons between the amino acid sequences of the dihydrolipoamide acetyltransferase (E2p) of Escherichia coli and several chloramphenicol acetyltransferases (CATs) have revealed some well-aligned homologies which may be indicative of an underlying structural homology between the catalytic (acetyltransferase) domain of E2p and CAT.
openaire   +2 more sources

Noncoding RNAs in Host–Microbiota Interaction

Animal Research and One Health, EarlyView.
The intricate interplay between gut microbiota and the host exerts a profound impact on host biological processes and disease development. This review highlights the pivotal role of noncoding RNAs (ncRNAs) in this interaction. Host ncRNAs regulate gene expression and microbiota composition, whereas microbial small RNAs (sRNAs) modulate host gene ...
Ziyi Zhao, Ni Li, Jingyi Xu, Jianrong Ren, Xiaojun Yang, Xinyi Li, Junhu Yao, Shengru Wu   +7 more
wiley   +1 more source

Construction and Characterization of Novel Shuttle Expression Vectors for Actinobacillus succinogenes

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Actinobacillus succinogenes is a ruminal microorganism of biotechnological importance due to its capacity to produce succinic acid at high yields. Despite the scientific interest in this organism, molecular vehicles for the transfer and expression of genetic material are limited compared to the existing demand.
Angélica Vallejo‐Giraldo, Luz María Martínez, Noemí Flores, Georgina Hernández‐Chávez, Fernanda Cueto, Alfredo Martinez, Rosa Isela Corona‐González, Guillermo Gosset   +7 more
wiley   +1 more source

Acetylation of histones and non-histone proteins is not a mere consequence of ongoing transcription

Nature Communications
In all eukaryotes, acetylation of histone lysine residues correlates with transcription activation. Whether histone acetylation is a cause or consequence of transcription is debated.
Tim Liebner, Sinan Kilic, Jonas Walter, Hitoshi Aibara, Takeo Narita, Chunaram Choudhary   +5 more
doaj   +1 more source

Isotopic exchange between acetylcholine and [Me-14C] choline catalysed by human placental choline acetyltransferase [PDF]

, 1969
David Morris, Darshan S. Grewaal
openalex   +1 more source

Arylamine N-acetyltransferases: from drug metabolism and pharmacogenetics to drug discovery

British Journal of Pharmacology, 2014
Arylamine N‐acetyltransferases (NATs) are polymorphic drug‐metabolizing enzymes, acetylating arylamine carcinogens and drugs including hydralazine and sulphonamides.
E. Sim, E. Sim, A. Abuhammad, A. Abuhammad, A. Ryan   +4 more
semanticscholar   +1 more source

Safety of sulfamethoxazole–trimethoprim for the treatment of bacterial infection in outpatient settings: A systematic review and meta‐analysis with active comparator disproportionality analysis

British Journal of Clinical Pharmacology, EarlyView.
Aims Sulfamethoxazole–trimethoprim (SMX‐TMP) is a widely used antibiotic for treating bacterial infections, but its safety in adult outpatients remains understudied. This systematic review and meta‐analysis evaluated the safety profile of SMX‐TMP and identified critical research gaps.
Rebecca Preyra, Lujain Ez Eddin, Fatemeh Ahmadi, Atefeh Jafari, Flory T. Muanda   +4 more
wiley   +1 more source

Dysregulation of Histone Acetyltransferases and Deacetylases in Cardiovascular Diseases

Oxidative Medicine and Cellular Longevity, 2014
Cardiovascular disease (CVD) remains a leading cause of mortality worldwide despite advances in its prevention and management. A comprehensive understanding of factors which contribute to CVD is required in order to develop more effective treatment ...
Yonggang Wang, X. Miao, Yucheng Liu, Fengsheng Li, Quan Liu, Jian Sun, L. Cai   +6 more
semanticscholar   +1 more source

5‐Aza combined with VPA reprograms human T lineage acute leukemia Jurkat cells into B‐cell‐like cells by epigenetic activation of PAX5

Biotechnology Progress, EarlyView.
Abstract Epigenetic regulation plays an important role in cell fate reprogramming. Here, we found that inhibitors of epigenetic modifiers, including VPA, TSA, and 5‐Aza‐2'‐deoxycytidine, can induce phenotypic transformation from Jurkat cells into B‐cell‐like cells. When Jurkat cells were treated with 5‐Aza combined with VPA, B cell and stem cell marker
Wenjin Xi, Guoxu Zheng, Xu Chen, Baile Zuo, Wei Wang, Yufang Li, Chunmei Zhang, Jie Chu, Xiuli Mu, Weihong Wen, Tao Wang, An‐Gang Yang   +11 more
wiley   +1 more source

A Review of the Effects of Curcumin on Histone Acetyltransferase Activity in the Prevention of Cardiac Hypertrophy

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2017
BACKGROUND AND OBJECTIVE: Curcumin, a natural polyphenolic compound derived from the rhizome of turmeric, has a cardiovascular protective effects. Histone acetyltransferase (HAT) is a consequential enzyme in processes of cardiac hypertrophy (cardiomegaly)
E Habibi, H Esmaeeli
doaj